Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SANR_RS03525 Genome accession   NC_022239
Coordinates   710938..711639 (+) Length   233 a.a.
NCBI ID   WP_020999538.1    Uniprot ID   -
Organism   Streptococcus anginosus C238     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 705938..716639
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SANR_RS03505 (SANR_0686) ccpA 706781..707785 (+) 1005 WP_020999536.1 catabolite control protein A Regulator
  SANR_RS03510 (SANR_0687) - 707965..708963 (+) 999 WP_020999537.1 glycosyltransferase family 4 protein -
  SANR_RS03515 (SANR_0688) - 708965..710278 (+) 1314 WP_003035045.1 glycosyltransferase family 4 protein -
  SANR_RS03520 (SANR_0689) - 710305..710637 (+) 333 WP_003035050.1 hypothetical protein -
  SANR_RS03525 (SANR_0690) micA 710938..711639 (+) 702 WP_020999538.1 response regulator YycF Regulator
  SANR_RS03530 (SANR_0691) micB 711632..712984 (+) 1353 WP_020999539.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SANR_RS03535 (SANR_0692) vicX 712986..713789 (+) 804 WP_003034882.1 MBL fold metallo-hydrolase Regulator
  SANR_RS03540 - 713798..714157 (+) 360 Protein_671 YbaN family protein -
  SANR_RS03545 (SANR_0693) rnc 714540..715238 (+) 699 WP_003035086.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26864.86 Da        Isoelectric Point: 4.7415

>NTDB_id=61670 SANR_RS03525 WP_020999538.1 710938..711639(+) (micA) [Streptococcus anginosus C238]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFNGREALEMFEAERPDILILDLMLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMPKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=61670 SANR_RS03525 WP_020999538.1 710938..711639(+) (micA) [Streptococcus anginosus C238]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATAAAATTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACAGCCTTCAATGGTCGTGAAGCATTAGAGATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTGA
TGTTGCCTGAACTGGACGGCTTAGAGGTGGCGCGAACGATTCGGAAAACGAGCAATGTTCCCATCATCGTTCTTTCTGCC
AAAGACAGTGAATTTGATAAAGTCATTGGTCTCGAAATCGGAGCAGATGATTATATGCCAAAGCCGTTTTCTAATCGTGA
GTTACAGGCGCGTGTCAAAGCTATTTTGCGTCGCACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCGACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGTGAAGAATTGGATTTAACACAC
CGTGAGTTTGAATTGCTGCACCATTTGGCAACGCATATCGGACAAGTGATGACGCGTGAACATCTGCTAGAAACGGTGTG
GGGTTATGATTATTTTGGAGATGTGCGGACTGTTGATGTGACAATTCGTCGTTTGAGAGAAAAGATAGAGGATATTCCTA
GCCGACCAGAGTACATTTTAACGCGGCGCGGCGTTGGATATTACATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.833

100

0.828
  vicR Streptococcus mutans UA159

78.814

100

0.798
  covR Streptococcus salivarius strain HSISS4

45.217

98.712

0.446
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.978

98.283

0.442
  scnR Streptococcus mutans UA159

36.052

100

0.361

Multiple sequence alignment