Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   LCF45_RS25275 Genome accession   NZ_CP084035
Coordinates   4892287..4892868 (+) Length   193 a.a.
NCBI ID   WP_001049156.1    Uniprot ID   J8DR96
Organism   Bacillus sp. 41-22     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 4887287..4897868
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LCF45_RS25240 (LCF45_25210) - 4888270..4888476 (+) 207 WP_000216167.1 DUF1657 domain-containing protein -
  LCF45_RS25245 (LCF45_25215) - 4888583..4889071 (+) 489 WP_002167400.1 YhcN/YlaJ family sporulation lipoprotein -
  LCF45_RS25250 (LCF45_25220) spoVAC 4889100..4889576 (+) 477 WP_002129887.1 stage V sporulation protein AC -
  LCF45_RS25255 (LCF45_25225) spoVAD 4889577..4890593 (+) 1017 WP_000938981.1 stage V sporulation protein AD -
  LCF45_RS25260 (LCF45_25230) spoVAE 4890590..4890940 (+) 351 WP_000575919.1 stage V sporulation protein AE -
  LCF45_RS25265 (LCF45_25235) - 4890950..4891156 (+) 207 WP_263894358.1 DUF1657 domain-containing protein -
  LCF45_RS25270 (LCF45_25240) - 4891177..4892046 (+) 870 WP_002016080.1 DUF421 domain-containing protein -
  LCF45_RS25275 (LCF45_25245) clpP 4892287..4892868 (+) 582 WP_001049156.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  LCF45_RS25280 (LCF45_25250) - 4893119..4893367 (-) 249 WP_002016081.1 HPr family phosphocarrier protein -
  LCF45_RS25285 (LCF45_25255) whiA 4893391..4894341 (-) 951 WP_002016082.1 DNA-binding protein WhiA -
  LCF45_RS25290 (LCF45_25260) - 4894430..4895383 (-) 954 WP_002016083.1 gluconeogenesis factor YvcK family protein -
  LCF45_RS25295 (LCF45_25265) rapZ 4895387..4896268 (-) 882 WP_002016084.1 RNase adapter RapZ -
  LCF45_RS25300 (LCF45_25270) - 4896289..4896747 (-) 459 WP_001190080.1 NUDIX hydrolase -
  LCF45_RS25305 (LCF45_25275) - 4896963..4897769 (-) 807 WP_002016085.1 DUF368 domain-containing protein -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21431.68 Da        Isoelectric Point: 5.0423

>NTDB_id=609190 LCF45_RS25275 WP_001049156.1 4892287..4892868(+) (clpP) [Bacillus sp. 41-22]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLESQDPEKDIHIYINSPGGSITAGMAIYDT
MQFIKPQVSTICIGMAASMGAFLLAAGEKGKRFALPNSEVMIHQPLGGAQGQATEIEIAAKRILFLREKLNQILADRTGQ
PLEVLQRDTDRDNFMTAERALEYGLIDKIFTNR

Nucleotide


Download         Length: 582 bp        

>NTDB_id=609190 LCF45_RS25275 WP_001049156.1 4892287..4892868(+) (clpP) [Bacillus sp. 41-22]
ATGAATTTAATTCCTACAGTAATTGAACAAACAAATCGTGGAGAACGCGCTTACGATATTTACTCTCGACTATTAAAGGA
TCGCATCATTATGCTTGGTAGCGCAATTGATGACAATGTAGCAAACTCAATCGTTTCCCAGCTTTTATTCTTGGAATCTC
AAGATCCAGAAAAAGATATTCACATTTACATCAACAGCCCTGGTGGTTCTATCACAGCTGGTATGGCAATTTACGATACA
ATGCAGTTTATTAAACCACAAGTATCAACAATCTGTATCGGTATGGCTGCATCTATGGGTGCATTCTTACTTGCAGCAGG
TGAAAAAGGAAAACGTTTCGCTCTTCCTAACAGTGAAGTAATGATTCACCAACCACTTGGCGGTGCACAAGGTCAAGCGA
CTGAAATCGAAATCGCTGCAAAACGTATCCTATTCTTACGTGAAAAATTAAACCAAATTCTTGCTGACCGCACAGGTCAA
CCACTTGAAGTTCTACAACGCGACACAGATCGCGACAACTTCATGACAGCAGAAAGAGCTCTAGAATACGGCTTAATCGA
TAAGATCTTTACAAATCGTTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J8DR96

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

89.583

99.482

0.891
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.553

97.409

0.658
  clpP Streptococcus thermophilus LMG 18311

60.938

99.482

0.606
  clpP Streptococcus thermophilus LMD-9

60.938

99.482

0.606
  clpP Lactococcus lactis subsp. cremoris KW2

59.375

99.482

0.591
  clpP Streptococcus pneumoniae D39

57.812

99.482

0.575
  clpP Streptococcus pneumoniae Rx1

57.812

99.482

0.575
  clpP Streptococcus pneumoniae R6

57.812

99.482

0.575
  clpP Streptococcus pneumoniae TIGR4

57.812

99.482

0.575
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

57.292

99.482

0.57
  clpP Streptococcus mutans UA159

55.959

100

0.56
  clpP Streptococcus pyogenes JRS4

56.25

99.482

0.56
  clpP Streptococcus pyogenes MGAS315

56.25

99.482

0.56