Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   K8M08_RS00225 Genome accession   NZ_CP083749
Coordinates   38705..39286 (+) Length   193 a.a.
NCBI ID   WP_000991609.1    Uniprot ID   A0A853X8N5
Organism   Bacillus sp. CRB-7     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 24180..39286 38705..39286 within 0


Gene organization within MGE regions


Location: 24180..39286
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8M08_RS00130 (K8M08_00130) - 24180..24956 (+) 777 WP_000450782.1 serine hydrolase -
  K8M08_RS00135 (K8M08_00135) - 24953..25324 (+) 372 WP_000828012.1 hypothetical protein -
  K8M08_RS00140 (K8M08_00140) - 25357..25773 (+) 417 WP_000809322.1 GNAT family N-acetyltransferase -
  K8M08_RS00145 (K8M08_00145) - 26050..26856 (+) 807 WP_000540642.1 GH25 family lysozyme -
  K8M08_RS00150 (K8M08_00150) - 26923..27135 (-) 213 WP_000820165.1 DUF3006 domain-containing protein -
  K8M08_RS00155 (K8M08_00155) - 27138..28523 (-) 1386 WP_042990568.1 S-layer homology domain-containing protein -
  K8M08_RS00160 (K8M08_00160) - 28954..29361 (+) 408 WP_000288950.1 GNAT family N-acetyltransferase -
  K8M08_RS00165 (K8M08_00165) - 29375..29728 (+) 354 WP_000859040.1 MmcQ/YjbR family DNA-binding protein -
  K8M08_RS00170 (K8M08_00170) - 29750..30457 (+) 708 WP_000655488.1 class I SAM-dependent methyltransferase -
  K8M08_RS00175 (K8M08_00175) - 30523..30918 (+) 396 WP_001093435.1 DUF2809 domain-containing protein -
  K8M08_RS00180 (K8M08_00180) - 30934..31863 (+) 930 WP_000502494.1 phosphotransferase enzyme family protein -
  K8M08_RS00185 (K8M08_00185) - 31860..32363 (+) 504 WP_000720536.1 DNA topology modulation protein -
  K8M08_RS00190 (K8M08_00190) - 32510..33190 (+) 681 WP_001058133.1 formylglycine-generating enzyme family protein -
  K8M08_RS00195 (K8M08_00195) - 33276..34469 (+) 1194 WP_000124911.1 macrolide family glycosyltransferase -
  K8M08_RS00200 (K8M08_00200) - 34827..36194 (+) 1368 WP_000797165.1 lytic polysaccharide monooxygenase -
  K8M08_RS00205 (K8M08_00205) - 36325..36759 (-) 435 WP_000555717.1 GNAT family N-acetyltransferase -
  K8M08_RS00210 (K8M08_00210) rpiA 36867..37529 (-) 663 WP_001050003.1 ribose 5-phosphate isomerase A -
  K8M08_RS00215 (K8M08_00215) - 37534..37854 (-) 321 WP_001125386.1 2Fe-2S iron-sulfur cluster-binding protein -
  K8M08_RS00220 (K8M08_00220) - 37997..38683 (+) 687 WP_000337513.1 RNA polymerase subunit sigma-70 -
  K8M08_RS00225 (K8M08_00225) clpP 38705..39286 (+) 582 WP_000991609.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21192.49 Da        Isoelectric Point: 5.3394

>NTDB_id=607627 K8M08_RS00225 WP_000991609.1 38705..39286(+) (clpP) [Bacillus sp. CRB-7]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIIIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAKGQATEIEITAKRILKLKHDINKMIAEKTGQ
PIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK

Nucleotide


Download         Length: 582 bp        

>NTDB_id=607627 K8M08_RS00225 WP_000991609.1 38705..39286(+) (clpP) [Bacillus sp. CRB-7]
ATGAATGCAATTCCATATGTAGTGGAACAAACGAAATTAGGAGAACGTTCTTATGATATATATTCAAGGTTATTAAAAGA
TCGTATTATTATTATCGGTTCAGAAATAAATGATCAAGTAGCCAGTAGTGTCGTAGCTCAATTATTATTTTTAGAAGCAG
AAGATGCAGAGAAAGATATATTTTTATACATTAATAGCCCCGGCGGATCAACGACAGCGGGATTTGCTATATTAGATACA
ATGAATTTAATTAAACCTGATGTGCAAACGCTATGCATGGGCTTTGCAGCATCATTTGGTGCATTGTTATTATTATCAGG
TGCAAAAGGAAAACGATTTGCACTCCCAAATAGTGAAATTATGATTCATCAGCCGCTTGGTGGTGCAAAAGGGCAGGCAA
CAGAAATTGAAATAACAGCAAAAAGGATATTGAAGTTAAAGCATGATATTAATAAAATGATTGCAGAAAAAACGGGGCAA
CCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACCGCAGAAGAAGCAAAGGCATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(14-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A853X8N5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

68.063

98.964

0.674
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.196

97.927

0.658
  clpP Streptococcus pyogenes JRS4

56.085

97.927

0.549
  clpP Streptococcus pyogenes MGAS315

56.085

97.927

0.549
  clpP Streptococcus pneumoniae R6

55.208

99.482

0.549
  clpP Streptococcus pneumoniae TIGR4

55.208

99.482

0.549
  clpP Streptococcus pneumoniae Rx1

55.208

99.482

0.549
  clpP Streptococcus thermophilus LMG 18311

55.208

99.482

0.549
  clpP Streptococcus thermophilus LMD-9

55.208

99.482

0.549
  clpP Streptococcus pneumoniae D39

55.208

99.482

0.549
  clpP Streptococcus mutans UA159

53.968

97.927

0.528
  clpP Lactococcus lactis subsp. cremoris KW2

51.852

97.927

0.508
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

50.265

97.927

0.492