Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   LA346_RS09325 Genome accession   NZ_CP083627
Coordinates   1797557..1798207 (+) Length   216 a.a.
NCBI ID   WP_000387329.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain FDAARGOS_1508     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 1795331..1796587 1797557..1798207 flank 970


Gene organization within MGE regions


Location: 1795331..1798207
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA346_RS09315 (LA346_09315) - 1795331..1796587 (-) 1257 WP_000530081.1 ISL3 family transposase -
  LA346_RS09320 (LA346_09320) - 1796920..1797489 (+) 570 WP_000443772.1 GNAT family N-acetyltransferase -
  LA346_RS09325 (LA346_09325) comEA/celA/cilE 1797557..1798207 (+) 651 WP_000387329.1 helix-hairpin-helix domain-containing protein Machinery gene

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23254.66 Da        Isoelectric Point: 5.9204

>NTDB_id=606858 LA346_RS09325 WP_000387329.1 1797557..1798207(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain FDAARGOS_1508]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVHKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEESVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=606858 LA346_RS09325 WP_000387329.1 1797557..1798207(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain FDAARGOS_1508]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCATAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAATCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-126)

Helix-hairpin-helix motif (HHH_3)

(151-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae D39

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae R6

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

96.296

100

0.963
  comEA/celA/cilE Streptococcus mitis NCTC 12261

95.37

100

0.954
  comEA/celA/cilE Streptococcus mitis SK321

90.278

100

0.903
  comEA Lactococcus lactis subsp. cremoris KW2

43.612

100

0.458
  comEA Bacillus subtilis subsp. subtilis str. 168

41.579

87.963

0.366
  comEA Latilactobacillus sakei subsp. sakei 23K

33.476

100

0.361