Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   LA346_RS03840 Genome accession   NZ_CP083627
Coordinates   703627..703950 (-) Length   107 a.a.
NCBI ID   WP_000738628.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain FDAARGOS_1508     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 698627..708950
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA346_RS03800 (LA346_03800) rnpA 698647..699018 (-) 372 WP_000739246.1 ribonuclease P protein component -
  LA346_RS10825 - 699035..699166 (-) 132 WP_000768904.1 hypothetical protein -
  LA346_RS03805 (LA346_03805) - 699167..700357 (-) 1191 WP_000167765.1 acetate kinase -
  LA346_RS03810 (LA346_03810) comYH 700408..701361 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  LA346_RS03815 (LA346_03815) - 701422..702014 (-) 593 Protein_731 class I SAM-dependent methyltransferase -
  LA346_RS03820 (LA346_03820) comGG/cglG 702117..702563 (-) 447 WP_001809944.1 competence type IV pilus minor pilin ComGG Machinery gene
  LA346_RS03825 (LA346_03825) comGF/cglF 702541..703002 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  LA346_RS03830 (LA346_03830) comGE/cglE 702965..703267 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  LA346_RS03835 (LA346_03835) comGD/cglD 703230..703664 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  LA346_RS03840 (LA346_03840) comGC/cglC 703627..703950 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  LA346_RS03845 (LA346_03845) comGB/cglB 703952..704968 (-) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  LA346_RS03850 (LA346_03850) comGA/cglA/cilD 704916..705857 (-) 942 WP_000249536.1 competence type IV pilus ATPase ComGA Machinery gene
  LA346_RS03855 (LA346_03855) - 705933..706298 (-) 366 WP_000286415.1 DUF1033 family protein -
  LA346_RS03860 (LA346_03860) - 706449..707507 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  LA346_RS03865 (LA346_03865) nagA 707670..708821 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 107 a.a.        Molecular weight: 12232.41 Da        Isoelectric Point: 9.8887

>NTDB_id=606822 LA346_RS03840 WP_000738628.1 703627..703950(-) (comGC/cglC) [Streptococcus pneumoniae strain FDAARGOS_1508]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQD
DGRITEEQAKAYKEYHDKQNTSQIVKD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=606822 LA346_RS03840 WP_000738628.1 703627..703950(-) (comGC/cglC) [Streptococcus pneumoniae strain FDAARGOS_1508]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGAC
GATGGACGCATCACGGAAGAACAGGCTAAAGCCTATAAAGAATACCATGATAAACAAAATACTAGTCAAATCGTTAAAGA
TTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

93.458

100

0.935
  comGC/cglC Streptococcus pneumoniae D39

94.175

96.262

0.907
  comGC/cglC Streptococcus pneumoniae R6

94.175

96.262

0.907
  comGC/cglC Streptococcus pneumoniae Rx1

94.175

96.262

0.907
  comGC/cglC Streptococcus pneumoniae TIGR4

93.204

96.262

0.897
  comGC/cglC Streptococcus mitis SK321

88.35

96.262

0.85
  comYC Streptococcus gordonii str. Challis substr. CH1

69.388

91.589

0.636
  comYC Streptococcus mutans UA140

64.211

88.785

0.57
  comYC Streptococcus mutans UA159

64.211

88.785

0.57
  comYC Streptococcus suis isolate S10

69.136

75.701

0.523
  comGC Lactococcus lactis subsp. cremoris KW2

54.639

90.654

0.495
  comGC Staphylococcus aureus MW2

48.837

80.374

0.393
  comGC Staphylococcus aureus N315

48.837

80.374

0.393
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

80.374

0.364