Detailed information    

insolico Bioinformatically predicted

Overview


Name   clpP   Type   Regulator
Locus tag   K8Z41_RS28090 Genome accession   NZ_CP083116
Coordinates   5439666..5440247 (-) Length   193 a.a.
NCBI ID   WP_001049162.1    Uniprot ID   A0A9W5QPC2
Organism   Bacillus thuringiensis strain SA11     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 5439666..5488895 5439666..5440247 within 0


Gene organization within MGE regions


Location: 5439666..5488895
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8Z41_RS28090 (K8Z41_28040) clpP 5439666..5440247 (-) 582 WP_001049162.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  K8Z41_RS28095 (K8Z41_28045) - 5440488..5441357 (-) 870 WP_000018924.1 DUF421 domain-containing protein -
  K8Z41_RS28100 (K8Z41_28050) - 5441378..5441584 (-) 207 WP_000215909.1 DUF1657 domain-containing protein -
  K8Z41_RS28105 (K8Z41_28055) spoVAE 5441596..5441946 (-) 351 WP_000575919.1 stage V sporulation protein AE -
  K8Z41_RS28110 (K8Z41_28060) spoVAD 5441943..5442959 (-) 1017 WP_000938972.1 stage V sporulation protein AD -
  K8Z41_RS28115 (K8Z41_28065) spoVAC 5442960..5443436 (-) 477 WP_000095408.1 stage V sporulation protein AC -
  K8Z41_RS28120 (K8Z41_28070) - 5443466..5443954 (-) 489 WP_001226064.1 YhcN/YlaJ family sporulation lipoprotein -
  K8Z41_RS28125 (K8Z41_28075) - 5444048..5444254 (-) 207 WP_000216166.1 DUF1657 domain-containing protein -
  K8Z41_RS28135 (K8Z41_28085) - 5444669..5445805 (-) 1137 WP_000135757.1 tyrosine-type recombinase/integrase -
  K8Z41_RS28140 (K8Z41_28090) - 5445836..5446303 (-) 468 WP_001037137.1 hypothetical protein -
  K8Z41_RS28145 (K8Z41_28095) - 5446314..5446706 (-) 393 WP_002133807.1 helix-turn-helix transcriptional regulator -
  K8Z41_RS28150 (K8Z41_28100) - 5446871..5447101 (+) 231 WP_000216290.1 helix-turn-helix transcriptional regulator -
  K8Z41_RS28155 (K8Z41_28105) - 5447137..5447370 (+) 234 WP_000711864.1 DUF771 domain-containing protein -
  K8Z41_RS28160 (K8Z41_28110) - 5447554..5447709 (+) 156 WP_000788383.1 hypothetical protein -
  K8Z41_RS28165 (K8Z41_28115) - 5447724..5448479 (+) 756 WP_001016247.1 phage regulatory protein -
  K8Z41_RS28170 (K8Z41_28120) - 5448491..5448679 (+) 189 WP_001187283.1 hypothetical protein -
  K8Z41_RS28175 (K8Z41_28125) - 5448706..5449149 (+) 444 WP_000453495.1 hypothetical protein -
  K8Z41_RS28180 (K8Z41_28130) - 5449167..5449880 (+) 714 WP_015382506.1 hypothetical protein -
  K8Z41_RS28185 (K8Z41_28135) - 5449880..5450095 (+) 216 WP_000355713.1 hypothetical protein -
  K8Z41_RS28190 (K8Z41_28140) - 5450025..5450366 (+) 342 WP_002133909.1 hypothetical protein -
  K8Z41_RS28195 (K8Z41_28145) - 5450460..5451413 (+) 954 WP_000510889.1 DnaD domain protein -
  K8Z41_RS28200 (K8Z41_28150) - 5451425..5451904 (+) 480 WP_000933908.1 hypothetical protein -
  K8Z41_RS28205 (K8Z41_28155) - 5451897..5452127 (+) 231 WP_000139235.1 hypothetical protein -
  K8Z41_RS28210 (K8Z41_28160) - 5452151..5452708 (+) 558 WP_001245738.1 hypothetical protein -
  K8Z41_RS28215 (K8Z41_28165) - 5452747..5453181 (+) 435 WP_000775809.1 hypothetical protein -
  K8Z41_RS28220 (K8Z41_28170) - 5453240..5453530 (+) 291 WP_001268031.1 hypothetical protein -
  K8Z41_RS28225 (K8Z41_28175) - 5453535..5453675 (+) 141 WP_000492043.1 hypothetical protein -
  K8Z41_RS28235 (K8Z41_28180) - 5453677..5454470 (+) 794 Protein_5510 prohibitin family protein -
  K8Z41_RS28240 (K8Z41_28185) - 5454553..5454807 (+) 255 WP_000520932.1 hypothetical protein -
  K8Z41_RS28245 (K8Z41_28190) - 5454843..5455538 (+) 696 WP_000858114.1 hypothetical protein -
  K8Z41_RS28250 (K8Z41_28195) - 5455583..5455894 (+) 312 WP_000590881.1 hypothetical protein -
  K8Z41_RS28255 (K8Z41_28200) recU 5455930..5456457 (+) 528 WP_000540086.1 Holliday junction resolvase RecU -
  K8Z41_RS28260 (K8Z41_28205) - 5456454..5456780 (+) 327 WP_015670520.1 hypothetical protein -
  K8Z41_RS28265 (K8Z41_28210) - 5456818..5457219 (+) 402 WP_003308641.1 hypothetical protein -
  K8Z41_RS28270 (K8Z41_28215) - 5457603..5458022 (-) 420 WP_000711194.1 type II toxin-antitoxin system HicB family antitoxin -
  K8Z41_RS28275 (K8Z41_28220) - 5458074..5458262 (-) 189 WP_306460290.1 type II toxin-antitoxin system HicA family toxin -
  K8Z41_RS28280 (K8Z41_28225) - 5458436..5458660 (+) 225 WP_000650576.1 hypothetical protein -
  K8Z41_RS28285 (K8Z41_28230) - 5458674..5458877 (+) 204 WP_000343502.1 hypothetical protein -
  K8Z41_RS28290 (K8Z41_28235) - 5458883..5459317 (+) 435 WP_001002014.1 hypothetical protein -
  K8Z41_RS28295 (K8Z41_28240) - 5459386..5459595 (+) 210 WP_001177575.1 hypothetical protein -
  K8Z41_RS28300 (K8Z41_28245) - 5459602..5459859 (+) 258 WP_000378699.1 hypothetical protein -
  K8Z41_RS28305 (K8Z41_28250) - 5459850..5460224 (+) 375 WP_001177571.1 hypothetical protein -
  K8Z41_RS28310 (K8Z41_28255) - 5460190..5460525 (+) 336 WP_000666398.1 HNH endonuclease -
  K8Z41_RS28315 (K8Z41_28260) - 5460650..5460961 (+) 312 WP_000301150.1 P27 family phage terminase small subunit -
  K8Z41_RS28320 (K8Z41_28265) - 5460958..5462643 (+) 1686 WP_000595321.1 terminase large subunit -
  K8Z41_RS28325 (K8Z41_28270) - 5462664..5463815 (+) 1152 WP_000118683.1 phage portal protein -
  K8Z41_RS28330 (K8Z41_28275) - 5463805..5464530 (+) 726 WP_000791073.1 head maturation protease, ClpP-related -
  K8Z41_RS28335 (K8Z41_28280) - 5464581..5465723 (+) 1143 WP_086401347.1 phage major capsid protein -
  K8Z41_RS28340 (K8Z41_28285) - 5465736..5466029 (+) 294 WP_000361981.1 hypothetical protein -
  K8Z41_RS28345 (K8Z41_28290) - 5466031..5466381 (+) 351 WP_001247297.1 phage head closure protein -
  K8Z41_RS28350 (K8Z41_28295) - 5466383..5466727 (+) 345 WP_000997537.1 HK97 gp10 family phage protein -
  K8Z41_RS28355 (K8Z41_28300) - 5466724..5467059 (+) 336 WP_000219080.1 hypothetical protein -
  K8Z41_RS28360 (K8Z41_28305) - 5467060..5467653 (+) 594 WP_001004920.1 major tail protein -
  K8Z41_RS28365 (K8Z41_28310) - 5467660..5468022 (+) 363 WP_000415931.1 hypothetical protein -
  K8Z41_RS28370 (K8Z41_28315) - 5468253..5469488 (+) 1236 WP_000897021.1 hypothetical protein -
  K8Z41_RS28375 (K8Z41_28320) - 5469766..5472147 (+) 2382 WP_002133928.1 hypothetical protein -
  K8Z41_RS28380 (K8Z41_28325) - 5472189..5473658 (+) 1470 WP_015382503.1 distal tail protein Dit -
  K8Z41_RS28385 (K8Z41_28330) - 5473655..5478037 (+) 4383 WP_015382502.1 phage tail spike protein -
  K8Z41_RS28390 (K8Z41_28335) - 5478054..5478425 (+) 372 WP_016090170.1 hypothetical protein -
  K8Z41_RS28395 (K8Z41_28340) - 5478546..5479739 (-) 1194 WP_000499524.1 IS110 family transposase -
  K8Z41_RS28400 (K8Z41_28345) - 5480034..5480477 (+) 444 WP_042991251.1 phage holin family protein -
  K8Z41_RS28405 (K8Z41_28350) - 5480539..5481732 (-) 1194 WP_000499524.1 IS110 family transposase -
  K8Z41_RS28410 (K8Z41_28355) - 5482030..5482965 (+) 936 WP_000405783.1 N-acetylmuramoyl-L-alanine amidase -
  K8Z41_RS28415 (K8Z41_28360) - 5483169..5484284 (+) 1116 WP_000993515.1 Rap family tetratricopeptide repeat protein -
  K8Z41_RS28420 (K8Z41_28365) - 5484284..5484502 (+) 219 WP_000734384.1 hypothetical protein -
  K8Z41_RS28425 (K8Z41_28370) - 5484681..5485247 (-) 567 WP_000742864.1 hypothetical protein -
  K8Z41_RS28430 (K8Z41_28375) - 5485391..5485609 (+) 219 WP_001016121.1 hypothetical protein -
  K8Z41_RS28435 (K8Z41_28380) - 5485634..5485927 (+) 294 WP_001273481.1 YolD-like family protein -
  K8Z41_RS28440 (K8Z41_28385) - 5485943..5486770 (-) 828 WP_000412580.1 helix-turn-helix domain-containing protein -
  K8Z41_RS28445 (K8Z41_28390) rpoN 5487333..5488640 (+) 1308 WP_000647955.1 RNA polymerase factor sigma-54 -
  K8Z41_RS28450 (K8Z41_28395) - 5488650..5488895 (+) 246 WP_000869730.1 glutaredoxin family protein -

Sequence


Protein


Download         Length: 193 a.a.        Molecular weight: 21419.67 Da        Isoelectric Point: 5.0423

>NTDB_id=604715 K8Z41_RS28090 WP_001049162.1 5439666..5440247(-) (clpP) [Bacillus thuringiensis strain SA11]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLESQDPEKDIHIYINSPGGSITAGMAIYDT
MQFIKPQVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILFLREKLNQILADRTGQ
PLEVLQRDTDRDNFMTAEKALEYGLIDKIFTNR

Nucleotide


Download         Length: 582 bp        

>NTDB_id=604715 K8Z41_RS28090 WP_001049162.1 5439666..5440247(-) (clpP) [Bacillus thuringiensis strain SA11]
ATGAATTTAATTCCTACAGTAATTGAACAAACAAATCGTGGAGAACGCGCTTACGATATTTACTCTCGACTATTAAAAGA
CCGCATCATTATGCTTGGTAGTGCAATTGATGACAACGTAGCTAACTCAATCGTTTCCCAGCTTTTATTCTTGGAATCTC
AAGATCCAGAAAAAGATATTCACATCTACATCAACAGCCCTGGTGGTTCTATCACAGCAGGTATGGCAATCTATGATACA
ATGCAGTTTATTAAACCACAAGTATCAACAATCTGTATCGGTATGGCAGCATCTATGGGTGCATTCTTACTTGCAGCAGG
TGAAAAAGGAAAACGTTATGCACTTCCAAACAGTGAAGTAATGATTCACCAACCACTTGGCGGAGCACAAGGTCAAGCGA
CTGAAATCGAAATCGCTGCAAAACGTATCCTATTCTTACGTGAAAAACTAAACCAAATTCTTGCTGACCGCACTGGTCAA
CCACTTGAAGTACTACAACGCGACACAGACCGCGACAACTTCATGACAGCAGAAAAAGCTTTAGAATACGGTTTAATCGA
TAAAATCTTTACAAATCGTTAA

Domains


Predicted by InterproScan.

(13-192)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

90.104

99.482

0.896

  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.021

97.409

0.653

  clpP Streptococcus thermophilus LMG 18311

60.417

99.482

0.601

  clpP Streptococcus thermophilus LMD-9

60.417

99.482

0.601

  clpP Lactococcus lactis subsp. cremoris KW2

58.854

99.482

0.585

  clpP Streptococcus pneumoniae D39

57.292

99.482

0.57

  clpP Streptococcus pneumoniae Rx1

57.292

99.482

0.57

  clpP Streptococcus pneumoniae R6

57.292

99.482

0.57

  clpP Streptococcus pneumoniae TIGR4

57.292

99.482

0.57

  clpP Lactococcus lactis subsp. lactis strain DGCC12653

56.771

99.482

0.565

  clpP Streptococcus pyogenes JRS4

55.729

99.482

0.554

  clpP Streptococcus pyogenes MGAS315

55.729

99.482

0.554

  clpP Streptococcus mutans UA159

55.44

100

0.554