Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   KX728_RS00830 Genome accession   NZ_CP079724
Coordinates   159166..159468 (+) Length   100 a.a.
NCBI ID   WP_000413364.1    Uniprot ID   A0A7H9FDI6
Organism   Streptococcus oralis strain 34     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 154166..164468
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KX728_RS00800 (KX728_00800) nagA 154844..155995 (+) 1152 WP_215805169.1 N-acetylglucosamine-6-phosphate deacetylase -
  KX728_RS00805 (KX728_00805) - 156147..156512 (+) 366 WP_000286399.1 DUF1033 family protein -
  KX728_RS00810 (KX728_00810) comGA/cglA/cilD 156576..157517 (+) 942 WP_215805168.1 competence type IV pilus ATPase ComGA Machinery gene
  KX728_RS00815 (KX728_00815) comGB/cglB 157465..158481 (+) 1017 WP_215805178.1 competence type IV pilus assembly protein ComGB Machinery gene
  KX728_RS00820 (KX728_00820) comGC/cglC 158483..158806 (+) 324 WP_215805167.1 competence type IV pilus major pilin ComGC Machinery gene
  KX728_RS00825 (KX728_00825) comGD/cglD 158769..159203 (+) 435 WP_215805166.1 competence type IV pilus minor pilin ComGD Machinery gene
  KX728_RS00830 (KX728_00830) comGE/cglE 159166..159468 (+) 303 WP_000413364.1 competence type IV pilus minor pilin ComGE Machinery gene
  KX728_RS00835 (KX728_00835) comGF/cglF 159431..159892 (+) 462 WP_215805165.1 competence type IV pilus minor pilin ComGF Machinery gene
  KX728_RS00840 (KX728_00840) comGG/cglG 159870..160283 (+) 414 WP_215805164.1 competence type IV pilus minor pilin ComGG Machinery gene
  KX728_RS00845 (KX728_00845) - 160316..160906 (+) 591 Protein_149 class I SAM-dependent methyltransferase -
  KX728_RS00850 (KX728_00850) comYH 160965..161918 (+) 954 WP_215805163.1 class I SAM-dependent methyltransferase Machinery gene
  KX728_RS00855 (KX728_00855) - 161969..163159 (+) 1191 WP_215805162.1 acetate kinase -
  KX728_RS00860 (KX728_00860) rnpA 163309..163680 (+) 372 WP_000748120.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11140.08 Da        Isoelectric Point: 7.0157

>NTDB_id=588951 KX728_RS00830 WP_000413364.1 159166..159468(+) (comGE/cglE) [Streptococcus oralis strain 34]
MEKLNALRKLKIKAVILLEAVVALAIFASIATLLLGQIQKNRQEEAEILQKEEVLRAAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEKLLDLKEQ

Nucleotide


Download         Length: 303 bp        

>NTDB_id=588951 KX728_RS00830 WP_000413364.1 159166..159468(+) (comGE/cglE) [Streptococcus oralis strain 34]
ATGGAAAAATTAAACGCATTAAGGAAACTAAAAATTAAGGCAGTGATCTTACTAGAAGCAGTAGTAGCGCTAGCCATATT
TGCCAGTATTGCAACCCTCCTTTTAGGACAAATTCAGAAAAATAGGCAGGAAGAGGCAGAAATCTTGCAAAAAGAGGAAG
TCTTACGTGCAGCGAAGATGGCTCTGCAGACAGGGCAAAATCAAGTAAACATAAACGGAGTGGAGATTCAGGTGTTTTCT
AGTGAAAAGGGATTGGAGGTCTACCATGGTTCAGAGAAGTTACTCGACCTTAAAGAGCAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-96)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H9FDI6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

91.919

99

0.91
  comGE/cglE Streptococcus pneumoniae Rx1

91.919

99

0.91
  comGE/cglE Streptococcus pneumoniae D39

91.919

99

0.91
  comGE/cglE Streptococcus pneumoniae R6

91.919

99

0.91
  comGE/cglE Streptococcus pneumoniae TIGR4

91.919

99

0.91
  comGE/cglE Streptococcus mitis SK321

90.909

99

0.9
  comYE Streptococcus mutans UA140

42.391

92

0.39
  comYE Streptococcus mutans UA159

42.391

92

0.39