Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   KU891_RS13175 Genome accession   NZ_CP078081
Coordinates   2571278..2571859 (-) Length   193 a.a.
NCBI ID   WP_000991609.1    Uniprot ID   A0A853X8N5
Organism   Bacillus tropicus strain EMB20     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2568997..2593637 2571278..2571859 within 0


Gene organization within MGE regions


Location: 2568997..2593637
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU891_RS13165 (KU891_13140) - 2568997..2570202 (-) 1206 WP_000370618.1 glycine betaine/L-proline ABC transporter ATP-binding protein -
  KU891_RS13170 (KU891_13145) - 2570374..2571231 (+) 858 WP_077316801.1 glycine betaine ABC transporter substrate-binding protein -
  KU891_RS13175 (KU891_13150) clpP 2571278..2571859 (-) 582 WP_000991609.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  KU891_RS13180 (KU891_13155) - 2571881..2572567 (-) 687 WP_000337513.1 RNA polymerase subunit sigma-70 -
  KU891_RS13185 (KU891_13160) - 2572710..2573030 (+) 321 WP_001125386.1 2Fe-2S iron-sulfur cluster-binding protein -
  KU891_RS13190 (KU891_13165) rpiA 2573035..2573697 (+) 663 WP_001050003.1 ribose 5-phosphate isomerase A -
  KU891_RS13195 (KU891_13170) - 2573805..2574239 (+) 435 WP_000555717.1 GNAT family N-acetyltransferase -
  KU891_RS13200 (KU891_13175) - 2574370..2575737 (-) 1368 WP_048554788.1 lytic polysaccharide monooxygenase -
  KU891_RS13205 (KU891_13180) - 2576095..2577288 (-) 1194 WP_074619789.1 macrolide family glycosyltransferase -
  KU891_RS13210 (KU891_13185) - 2577374..2578054 (-) 681 WP_248139296.1 SUMF1/EgtB/PvdO family nonheme iron enzyme -
  KU891_RS13215 (KU891_13190) - 2578201..2578704 (-) 504 WP_074562440.1 DNA topology modulation protein -
  KU891_RS13220 (KU891_13195) - 2578701..2579630 (-) 930 WP_000502494.1 phosphotransferase -
  KU891_RS13225 (KU891_13200) - 2579646..2580041 (-) 396 WP_001093435.1 DUF2809 domain-containing protein -
  KU891_RS13230 (KU891_13205) - 2580107..2580814 (-) 708 WP_071715675.1 class I SAM-dependent methyltransferase -
  KU891_RS13235 (KU891_13210) - 2580836..2581189 (-) 354 WP_000859040.1 MmcQ/YjbR family DNA-binding protein -
  KU891_RS13240 (KU891_13215) - 2581203..2581610 (-) 408 WP_000288950.1 GNAT family N-acetyltransferase -
  KU891_RS13245 (KU891_13220) - 2582041..2583426 (+) 1386 WP_042990568.1 S-layer homology domain-containing protein -
  KU891_RS13250 (KU891_13225) - 2583429..2583641 (+) 213 WP_000820165.1 DUF3006 domain-containing protein -
  KU891_RS13255 (KU891_13230) - 2583707..2584513 (-) 807 WP_000540642.1 GH25 family lysozyme -
  KU891_RS13260 (KU891_13235) - 2584790..2585206 (-) 417 WP_000809322.1 GNAT family N-acetyltransferase -
  KU891_RS13265 (KU891_13240) - 2585239..2585610 (-) 372 WP_061402936.1 hypothetical protein -
  KU891_RS13270 (KU891_13245) - 2585607..2586383 (-) 777 WP_074619793.1 serine hydrolase -
  KU891_RS13275 (KU891_13250) - 2586528..2587040 (-) 513 WP_061402937.1 GNAT family N-acetyltransferase -
  KU891_RS13280 (KU891_13255) - 2587075..2588085 (-) 1011 WP_248139297.1 hypothetical protein -
  KU891_RS13285 (KU891_13260) - 2588072..2588419 (-) 348 WP_074619795.1 PadR family transcriptional regulator -
  KU891_RS13290 (KU891_13265) - 2588601..2588921 (-) 321 WP_248139298.1 DUF952 domain-containing protein -
  KU891_RS13295 (KU891_13270) - 2589004..2591079 (-) 2076 WP_248139299.1 3'-5' exonuclease -
  KU891_RS13300 (KU891_13275) - 2591445..2592311 (+) 867 WP_000127494.1 type II CAAX endopeptidase family protein -
  KU891_RS13305 (KU891_13280) - 2592332..2593075 (-) 744 WP_001004307.1 class I SAM-dependent methyltransferase -
  KU891_RS13310 (KU891_13285) - 2593254..2593637 (-) 384 WP_000559541.1 gamma-glutamylcyclotransferase -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21192.49 Da        Isoelectric Point: 5.3394

>NTDB_id=586604 KU891_RS13175 WP_000991609.1 2571278..2571859(-) (clpP) [Bacillus tropicus strain EMB20]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIIIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAKGQATEIEITAKRILKLKHDINKMIAEKTGQ
PIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK

Nucleotide


Download         Length: 582 bp        

>NTDB_id=586604 KU891_RS13175 WP_000991609.1 2571278..2571859(-) (clpP) [Bacillus tropicus strain EMB20]
ATGAATGCAATTCCATATGTAGTGGAACAAACGAAATTAGGAGAACGTTCCTATGATATATATTCAAGGTTATTAAAAGA
TCGTATTATTATTATCGGTTCAGAAATAAATGATCAAGTAGCCAGTAGTGTCGTAGCTCAATTATTATTTTTAGAAGCAG
AAGATGCAGAGAAAGATATATTTTTATACATTAATAGCCCCGGCGGATCAACGACAGCGGGATTTGCTATATTAGATACA
ATGAATTTAATTAAACCTGATGTGCAAACGCTATGCATGGGCTTTGCAGCATCATTTGGTGCATTGTTATTATTATCAGG
TGCAAAAGGAAAACGATTTGCACTCCCAAATAGTGAAATTATGATTCATCAGCCGCTTGGTGGTGCAAAAGGGCAGGCAA
CAGAAATTGAAATAACAGCAAAAAGGATATTGAAGTTAAAGCATGATATTAATAAAATGATTGCAGAAAAAACGGGGCAA
CCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACCGCAGAAGAAGCAAAGGCATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(14-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A853X8N5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

68.063

98.964

0.674
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.196

97.927

0.658
  clpP Streptococcus pyogenes JRS4

56.085

97.927

0.549
  clpP Streptococcus pyogenes MGAS315

56.085

97.927

0.549
  clpP Streptococcus pneumoniae R6

55.208

99.482

0.549
  clpP Streptococcus pneumoniae TIGR4

55.208

99.482

0.549
  clpP Streptococcus pneumoniae Rx1

55.208

99.482

0.549
  clpP Streptococcus thermophilus LMG 18311

55.208

99.482

0.549
  clpP Streptococcus thermophilus LMD-9

55.208

99.482

0.549
  clpP Streptococcus pneumoniae D39

55.208

99.482

0.549
  clpP Streptococcus mutans UA159

53.968

97.927

0.528
  clpP Lactococcus lactis subsp. cremoris KW2

51.852

97.927

0.508
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

50.265

97.927

0.492