Detailed information NTG0586251

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: KV238_RS03200
• Genome accession: NZ_CP078012
• Coordinates: 645594..646508 (-)
• Length: 304 a.a.
• NCBI ID: WP_043030321.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ_18-036
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 640594..651508

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KV238_RS03180 (KV238_03170)	-	641487..643268 (-)	1782	WP_111689737.1	acyltransferase family protein	-
KV238_RS03185 (KV238_03175)	-	643265..643666 (-)	402	WP_043984005.1	MORN repeat-containing protein	-
KV238_RS03190 (KV238_03180)	-	643672..644130 (-)	459	WP_043984007.1	low molecular weight protein-tyrosine-phosphatase	-
KV238_RS03195 (KV238_03185)	ruvB	644378..645379 (-)	1002	WP_042669757.1	Holliday junction branch migration DNA helicase RuvB	-
KV238_RS10800 (KV238_03190)	comS	645413..645511 (-)	99	WP_021320241.1	quorum-sensing system DWW-type pheromone	Regulator
KV238_RS03200 (KV238_03195)	comR	645594..646508 (-)	915	WP_043030321.1	helix-turn-helix domain-containing protein	Regulator
KV238_RS03205 (KV238_03200)	purB	646806..648098 (-)	1293	WP_041790267.1	adenylosuccinate lyase	-
KV238_RS03210 (KV238_03205)	-	648695..648919 (-)	225	WP_012677202.1	hypothetical protein	-
KV238_RS03215 (KV238_03210)	purK	648934..650007 (-)	1074	WP_043024882.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
KV238_RS03220 (KV238_03215)	purE	649994..650482 (-)	489	WP_021320238.1	5-(carboxyamino)imidazole ribonucleotide mutase	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35818.40 Da
• Isoelectric Point: 4.5517

>NTDB_id=586251 KV238_RS03200 WP_043030321.1 645594..646508(-) (comR) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVFIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIVGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKPEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDIEMAKKCYDKACLFAQLTGDQYLEKKLREEWGKDIKRYQ

Nucleotide

• Length: 915 bp

>NTDB_id=586251 KV238_RS03200 WP_043030321.1 645594..646508(-) (comR) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTTCGGTATCAGAAAAAAATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTGGCACGAATAGAACTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTTTATTG
CTAAGGCTTTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTACCGAAGCGCTATAAGGAGCTTAAA
TATTTGATTTTAAGAACACCGACCTATATGGACGATGACAAATTAAAGCTACGTGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGATCAGCTGCCAGAGGAAGAAAAGCTTGTGGTGGACTGCTTGCAGTCCATAATGGATACGTTATTAACTG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAGACAAAAAGCAAGACTCAATTTAGAGAGAATGAC
CTTATTCTTATTGAGCTGTATTTAGCGTATCTGGATATTGTGGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTATTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATTGTCAATAAAATAGCTATAG
GAATTTCCTCGTTGAGCATCAAAAACAATAAGCCGGAGATTCTTGAGAAGGTTATTGTACTTAGTCAAAAAATTATCCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATATGCTCTAATGAAGAAAAAAGACATAGA
AATGGCCAAAAAATGCTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTGGAAAAGAAATTGAGAG
AAGAATGGGGTAAAGATATAAAACGATATCAATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix domain (HTH_19) (6-69)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.587	99.671	0.743
comR	Streptococcus pyogenes MGAS315	54.817	99.013	0.543
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.724	95.395	0.493
comR	Streptococcus mutans UA159	49.164	98.355	0.484
comR	Streptococcus suis P1/7	38.255	98.026	0.375
comR	Streptococcus suis D9	37.542	99.013	0.372
comR	Streptococcus suis 05ZYH33	38.305	97.039	0.372