Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   KV238_RS00215 Genome accession   NZ_CP078012
Coordinates   43659..44369 (-) Length   236 a.a.
NCBI ID   WP_012515994.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ_18-036     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 38659..49369
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KV238_RS00200 (KV238_00195) - 39567..41309 (-) 1743 WP_230923664.1 restriction endonuclease FokI C-terminal domain-containing protein -
  KV238_RS00205 (KV238_00200) vicX 41501..42310 (-) 810 WP_043040861.1 MBL fold metallo-hydrolase Regulator
  KV238_RS00210 (KV238_00205) vicK 42314..43666 (-) 1353 WP_012677636.1 cell wall metabolism sensor histidine kinase VicK Regulator
  KV238_RS00215 (KV238_00210) vicR 43659..44369 (-) 711 WP_012515994.1 response regulator YycF Regulator
  KV238_RS00220 (KV238_00215) - 44568..45587 (-) 1020 WP_043040868.1 DUF3114 domain-containing protein -
  KV238_RS00225 (KV238_00220) - 45632..46894 (-) 1263 WP_043040863.1 AMP-binding protein -
  KV238_RS00230 (KV238_00225) - 46884..47999 (-) 1116 WP_230923665.1 acetyl-CoA C-acyltransferase -
  KV238_RS00235 (KV238_00230) - 47996..48535 (-) 540 WP_230923666.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 26981.84 Da        Isoelectric Point: 4.9038

>NTDB_id=586223 KV238_RS00215 WP_012515994.1 43659..44369(-) (vicR) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKAYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=586223 KV238_RS00215 WP_012515994.1 43659..44369(-) (vicR) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
ATGAAGAAAATACTGATTGTTGATGATGAAAAGCCGATTTCTGATATCATTAAATTTAATCTGACAAAGGAAGGCTATGA
TACGGTCACAGCATTTGATGGCAAAGAGGCCGTTGCAGTCTTTGAAGAGGAAAAGCCAGATTTGATTATTTTGGATTTGA
TGCTTCCTGAATTAGATGGCCTTGAGGTAGCCAAGGAAATCCGCAAGACCAGCCATATTCCTATCATCATGCTATCTGCT
AAGGATAGCGAATTTGATAAGGTGATTGGACTTGAAATAGGGGCTGATGATTATGTGACTAAGCCCTTTTCAAATCGTGA
GCTGCTGGCGCGTGTCAAGGCACATTTGCGTCGGACAGAGACTATTGAGACAGCAGTAGCCGAAGAAAATGCCTCCTCAG
GCTCTCAGGAGCTAACCATCGGCAATCTACAGATTTTACCAGATGCCTTTATCGCTAAAAAGCATGGTCAAGAGGTTGAG
CTGACCCATCGTGAGTTTGAATTGCTGCATCATCTGGCAAACCATATCGGACAGGTCATGACACGTGAGCATTTGCTTGA
GACCGTATGGGGCTACGATTATTTTGGCGATGTCCGAACCGTTGACGTTACTATCCGTCGCCTGCGCGAAAAAATAGAGG
ATACACCGAGTCGTCCAGAGTATATTTTGACAAGACGTGGTGTTGGGTACTACATGAAGGCTTATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

88.983

100

0.89
  micA Streptococcus pneumoniae Cp1015

78.112

98.729

0.771
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

38.034

99.153

0.377