Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   KV238_RS00210 Genome accession   NZ_CP078012
Coordinates   42314..43666 (-) Length   450 a.a.
NCBI ID   WP_012677636.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ_18-036     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 37314..48666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KV238_RS00195 (KV238_00190) - 37615..39546 (+) 1932 WP_230923663.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  KV238_RS00200 (KV238_00195) - 39567..41309 (-) 1743 WP_230923664.1 restriction endonuclease FokI C-terminal domain-containing protein -
  KV238_RS00205 (KV238_00200) vicX 41501..42310 (-) 810 WP_043040861.1 MBL fold metallo-hydrolase Regulator
  KV238_RS00210 (KV238_00205) vicK 42314..43666 (-) 1353 WP_012677636.1 cell wall metabolism sensor histidine kinase VicK Regulator
  KV238_RS00215 (KV238_00210) vicR 43659..44369 (-) 711 WP_012515994.1 response regulator YycF Regulator
  KV238_RS00220 (KV238_00215) - 44568..45587 (-) 1020 WP_043040868.1 DUF3114 domain-containing protein -
  KV238_RS00225 (KV238_00220) - 45632..46894 (-) 1263 WP_043040863.1 AMP-binding protein -
  KV238_RS00230 (KV238_00225) - 46884..47999 (-) 1116 WP_230923665.1 acetyl-CoA C-acyltransferase -
  KV238_RS00235 (KV238_00230) - 47996..48535 (-) 540 WP_230923666.1 hypothetical protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51541.94 Da        Isoelectric Point: 5.5557

>NTDB_id=586222 KV238_RS00210 WP_012677636.1 42314..43666(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=586222 KV238_RS00210 WP_012677636.1 42314..43666(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
ATGACTAAGGACATCATTGGAAACCTTTCTGCATTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCACAAGATAAGAGATTTAATCAATG
GTCGCTATACTGATACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAATGACCTATCAGAT
GTTTTTCGTCTGACTCATGAAAACCTTGCTCAAGAAAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGCGAGCAGG
CCTTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCACCTTACACCTACCGAGAGCTGGTCTCAAAAACACCGATT
GTGACCTTAAACCGTCGTAATGATACAGGAGAATTTGTTTCCCTGCGGCTGCGCTTTGCGCTTAATAGGCGAGAAAGCGG
CTTTATTTCAGGTCTAGTTGTTGTGCTTCATGACACGACTGAGCAGGAAAAGGAGGAGCGTGAGCGCAGACTCTTTGTCT
CAAATGTTAGCCATGAGCTTCGCACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCGCTAAAG
GAGGACATAGCCCCAAGCTTTATAAAGGTCTCACTAGACGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
TCTATCAAGAATTGATAATCATGTGACACAGCTGTCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACAAGCACAGGAAAATCCTATGAAATTGTCAGAGATTACCCTATTACCTCT
ATTTGGCTAGAAATTGATAACGATAAAATGACGCAGGTCATTGAAAATATTTTAAACAATGCCATCAAATATTCACCTGA
TGGTGGGAAAATTATCGTAAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGTTTGGGCATTC
CAAAAAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGAAGTCGGGCTCAAGGAGGAACTGGT
CTAGGCTTAGCGATTGCTAAAGAAATTATTAAGCAGCACCGCGGCTTTATCTGGGCTAAGAGTGACTATGGCAAGGGGTC
AACCTTTACCATTGTGTTACCTTACGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92

0.678
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631