Detailed information NTG0586087

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: MZN68_RS10110
• Genome accession: NZ_CP096117
• Coordinates: 2007225..2008412 (+)
• Length: 395 a.a.
• NCBI ID: WP_015815969.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain DFS-1910310016
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2002225..2013412

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MZN68_RS10095 (MZN68_09925)	-	2003145..2003744 (+)	600	WP_003690128.1	DUF4390 domain-containing protein	-
MZN68_RS10100 (MZN68_09930)	-	2003744..2005864 (+)	2121	WP_237986286.1	PAS domain-containing sensor histidine kinase	-
MZN68_RS10105 (MZN68_09935)	-	2005857..2007134 (+)	1278	WP_076612526.1	sigma-54 dependent transcriptional regulator	-
MZN68_RS10110 (MZN68_09940)	dprA	2007225..2008412 (+)	1188	WP_015815969.1	DNA-processing protein DprA	Machinery gene
MZN68_RS10115 (MZN68_09945)	-	2008438..2008899 (+)	462	WP_002215351.1	DUF494 domain-containing protein	-
MZN68_RS10120 (MZN68_09950)	topA	2008971..2011277 (+)	2307	WP_002234458.1	type I DNA topoisomerase	-
MZN68_RS10125 (MZN68_09955)	-	2011350..2012045 (-)	696	WP_002233407.1	hypothetical protein	-
MZN68_RS10130 (MZN68_09960)	-	2012736..2013113 (+)	378	WP_002233408.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 41815.84 Da
• Isoelectric Point: 6.1732

>NTDB_id=586087 MZN68_RS10110 WP_015815969.1 2007225..2008412(+) (dprA) [Neisseria meningitidis strain DFS-1910310016]
MTEDERFAWLQLAFTPYIGAESFLLLLRRFGSASNALSAPAEQVAPAVRHKQAAEAWRNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGRALGEKGIPVVSGMASGIDT
AAHQGALQAEGGTIAVWGTGIDRIYPPSNKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLTECLDDILNECPGLLQNTGASSYSINKDTSDTGSRAVQA
AYAPPPAAKMPSEGAAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=586087 MZN68_RS10110 WP_015815969.1 2007225..2008412(+) (dprA) [Neisseria meningitidis strain DFS-1910310016]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGCTTCCTGCTGCTGCT
GCGCCGTTTCGGCAGCGCGTCAAACGCCCTGTCCGCACCGGCGGAACAGGTCGCCCCGGCGGTGCGGCACAAGCAGGCGG
CCGAGGCTTGGCGCAATGCGGAAAAACGCGCTTTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGCCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGAGAGAAAGGCATTCCCGTTGTGTCGGGTATGGCTTCGGGCATCGATACC
GCCGCCCATCAGGGTGCGTTGCAGGCGGAAGGCGGCACCATCGCCGTGTGGGGGACGGGCATAGACCGCATTTATCCGCC
GTCCAATAAAAACCTTGCCTATGAAATCGCCGAAAAAGGACTGATTGTCAGCGAGTTCCCCATCGGCACGCGCCCGTATG
CCGGCAATTTTCCGCGCCGCAACCGCCTGATTGCCGCGCTGTCGCAGGTTACGCTGGTGGTTGAAGCCGCGTTGGAATCC
GGTTCGCTGATTACCGCCGGCCTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGTTCGATAGACAATCCACA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCGAAACTGACGGAATGTTTGGACGACATCCTGAACGAATGCCCGG
GTCTATTGCAAAATACGGGTGCTTCGTCATATTCTATAAATAAGGATACGTCCGACACGGGCAGCCGCGCCGTTCAGGCG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGGGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCCATCCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterProScan.

• DNA recombination-mediator protein A (DNA_processg_A) (79-282)

• DprA winged helix domain (WHD_DprA) (341-388)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae MS11	96.709	100	0.967
dprA	Neisseria gonorrhoeae strain FA1090	96.456	100	0.965
dprA	Neisseria meningitidis MC58	89.673	100	0.901
dprA	Neisseria meningitidis strain C311	89.673	100	0.901
dprA	Glaesserella parasuis strain SC1401	40.576	96.709	0.392
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	37.975	100	0.38
dprA	Vibrio cholerae strain A1552	37.975	100	0.38