Detailed information NTG0585636

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: KVP03_RS01675
• Genome accession: NZ_CP077959
• Coordinates: 345219..346133 (+)
• Length: 304 a.a.
• NCBI ID: WP_111692077.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ_14-145
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 340219..351133

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KVP03_RS01655 (KVP03_01650)	purE	341372..341860 (+)	489	WP_111692074.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
KVP03_RS01660 (KVP03_01655)	purK	341847..342941 (+)	1095	WP_230923161.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
KVP03_RS01665 (KVP03_01660)	-	342951..343175 (+)	225	WP_012514713.1	hypothetical protein	-
KVP03_RS10570	-	343218..343490 (+)	273	WP_372585987.1	hypothetical protein	-
KVP03_RS01670 (KVP03_01665)	purB	343629..344921 (+)	1293	WP_111692076.1	adenylosuccinate lyase	-
KVP03_RS01675 (KVP03_01670)	comR	345219..346133 (+)	915	WP_111692077.1	helix-turn-helix domain-containing protein	Regulator
KVP03_RS10575 (KVP03_01675)	comS	346216..346314 (+)	99	WP_021320241.1	quorum-sensing system DWW-type pheromone	Regulator
KVP03_RS01680 (KVP03_01680)	ruvB	346348..347349 (+)	1002	WP_230923162.1	Holliday junction branch migration DNA helicase RuvB	-
KVP03_RS01685 (KVP03_01685)	-	347597..348055 (+)	459	WP_111692078.1	low molecular weight protein-tyrosine-phosphatase	-
KVP03_RS01690 (KVP03_01690)	-	348061..348462 (+)	402	WP_012514718.1	MORN repeat-containing protein	-
KVP03_RS01695 (KVP03_01695)	-	348459..350240 (+)	1782	WP_043029239.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35790.34 Da
• Isoelectric Point: 4.5517

>NTDB_id=585636 KVP03_RS01675 WP_111692077.1 345219..346133(+) (comR) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVFIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIAGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKPEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDIEMAKKCYDKACLFAQLTGDQYLEKKLREEWGKDIKRYQ

Nucleotide

• Length: 915 bp

>NTDB_id=585636 KVP03_RS01675 WP_111692077.1 345219..346133(+) (comR) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTGCGGTATCAGAAGAAGATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTAGCACGAATAGAATTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTTTATTG
CTAAGGCTCTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAACTGCCTAAGCGTTATAAAGAACTTAAA
TATTTGATTTTAAGAACGCCGACCTATATGGATGATGACAAATTAAAGCTGCGAGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGACCAGTTGCCAGAGGAAGAAAAGCTTGTGGTGGATTGCTTGCAGTCCATAATGGATACGTTATTAACCG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAAACAAAAAGTAAGACTCAATTTAGAGAGAATGAT
CTCATTCTTATTGAGCTGTATTTAGCGTACCTCGACATTGCAGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTGTTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATTGTCAATAAAATAGCTATAG
GAATTTCCTCGTTGAGTATCAAAAACAATAAGCCGGAGATTCTTGAGAAGGTTATTGTACTTAGTCAAAAAATTATCCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATATGCTCTAATGAAGAAAAAAGACATAGA
AATGGCCAAAAAATGCTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTGGAAAAGAAATTGAGAG
AAGAATGGGGTAAAGATATAAAACGATATCAATAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix domain (HTH_19) (6-69)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.587	99.671	0.743
comR	Streptococcus pyogenes MGAS315	54.817	99.013	0.543
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	52.069	95.395	0.497
comR	Streptococcus mutans UA159	49.164	98.355	0.484
comR	Streptococcus suis D9	37.542	99.013	0.372
comR	Streptococcus suis 05ZYH33	38.305	97.039	0.372
comR	Streptococcus suis P1/7	38.305	97.039	0.372