Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   I872_RS05710 Genome accession   NC_021175
Coordinates   1146970..1147671 (-) Length   233 a.a.
NCBI ID   WP_015605198.1    Uniprot ID   -
Organism   Streptococcus cristatus AS 1.3089     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1141970..1152671
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I872_RS05690 (I872_05715) rnc 1143318..1144004 (-) 687 WP_015605194.1 ribonuclease III -
  I872_RS05695 (I872_05720) - 1144149..1144508 (-) 360 WP_015605195.1 YbaN family protein -
  I872_RS05700 (I872_05725) vicX 1144820..1145620 (-) 801 WP_015605196.1 MBL fold metallo-hydrolase Regulator
  I872_RS05705 (I872_05730) micB 1145613..1146977 (-) 1365 WP_015605197.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I872_RS05710 (I872_05735) micA 1146970..1147671 (-) 702 WP_015605198.1 response regulator YycF Regulator
  I872_RS05715 (I872_05740) - 1147934..1149016 (+) 1083 WP_015605199.1 M24 family metallopeptidase -
  I872_RS05720 (I872_05745) - 1149092..1149571 (-) 480 WP_041826807.1 hypothetical protein -
  I872_RS05725 (I872_05750) - 1149841..1150290 (-) 450 WP_015605201.1 Rrf2 family transcriptional regulator -
  I872_RS05735 (I872_05760) - 1150790..1151632 (-) 843 WP_015605203.1 metallophosphoesterase family protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26832.82 Da        Isoelectric Point: 4.8934

>NTDB_id=58451 I872_RS05710 WP_015605198.1 1146970..1147671(-) (micA) [Streptococcus cristatus AS 1.3089]
MKKILVVDDEKPISDIIKFNMTKEGYEVLTAFDGKEALEMFEVEQPDILILDLMLPEVDGLDVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKALLRRSELIPDSHVDESSPKELFIGDLQILPDAFVVKKHGKELELTH
REFELLHHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYIRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=58451 I872_RS05710 WP_015605198.1 1146970..1147671(-) (micA) [Streptococcus cristatus AS 1.3089]
ATGAAAAAAATATTAGTTGTAGATGACGAGAAGCCAATCTCGGACATTATAAAGTTTAATATGACCAAGGAAGGTTATGA
AGTGCTGACTGCCTTTGATGGTAAGGAAGCCTTGGAAATGTTTGAAGTGGAGCAACCAGACATCTTGATTCTGGACTTGA
TGTTGCCAGAAGTGGATGGACTTGATGTTGCTCGGACCATTCGTAAGACCAGCAATGTTCCAATCATTGTGCTTTCGGCC
AAAGATAGCGAGTTCGATAAGGTAATCGGTCTGGAAATCGGTGCTGATGACTATGTGACCAAGCCCTTTTCAAATCGTGA
ATTGCTGGCTCGGGTCAAGGCCTTGCTGCGCCGTTCTGAACTCATCCCAGATAGTCATGTGGATGAGAGTAGTCCAAAGG
AATTGTTTATTGGAGATTTGCAGATTCTTCCAGATGCTTTTGTGGTGAAAAAACACGGGAAAGAATTGGAATTAACCCAT
CGTGAATTTGAACTCTTGCACCATTTGGCGACCCATGTCGGTCAAGTCATGACACGTGAACACTTACTAGAAACGGTCTG
GGGTTATGATTACTTCGGTGATGTGCGGACTGTTGATGTGACCATTCGTCGTCTGCGCGAAAAAATCGAAGATACTCCAA
GCCGTCCAGAGTACATCTTGACTCGCCGCGGTGTCGGTTATTACATAAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

100

0.82
  vicR Streptococcus mutans UA159

79.149

100

0.798
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.978

98.283

0.442
  covR Streptococcus salivarius strain HSISS4

42.795

98.283

0.421
  scnR Streptococcus mutans UA159

36.957

98.712

0.365

Multiple sequence alignment