Detailed information NTG0058450

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: I872_RS05705
• Genome accession: NC_021175
• Coordinates: 1145613..1146977 (-)
• Length: 454 a.a.
• NCBI ID: WP_015605197.1
• Uniprot ID: -
• Organism: Streptococcus cristatus AS 1.3089
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1140613..1151977

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I872_RS05690 (I872_05715)	rnc	1143318..1144004 (-)	687	WP_015605194.1	ribonuclease III	-
I872_RS05695 (I872_05720)	-	1144149..1144508 (-)	360	WP_015605195.1	YbaN family protein	-
I872_RS05700 (I872_05725)	vicX	1144820..1145620 (-)	801	WP_015605196.1	MBL fold metallo-hydrolase	Regulator
I872_RS05705 (I872_05730)	micB	1145613..1146977 (-)	1365	WP_015605197.1	cell wall metabolism sensor histidine kinase VicK	Regulator
I872_RS05710 (I872_05735)	micA	1146970..1147671 (-)	702	WP_015605198.1	response regulator YycF	Regulator
I872_RS05715 (I872_05740)	-	1147934..1149016 (+)	1083	WP_015605199.1	M24 family metallopeptidase	-
I872_RS05720 (I872_05745)	-	1149092..1149571 (-)	480	WP_041826807.1	hypothetical protein	-
I872_RS05725 (I872_05750)	-	1149841..1150290 (-)	450	WP_015605201.1	Rrf2 family transcriptional regulator	-
I872_RS05735 (I872_05760)	-	1150790..1151632 (-)	843	WP_015605203.1	metallophosphoesterase family protein	-

Sequence

Protein

• Length: 454 a.a.
• Molecular weight: 51614.58 Da
• Isoelectric Point: 4.5423

>NTDB_id=58450 I872_RS05705 WP_015605197.1 1145613..1146977(-) (micB) [Streptococcus cristatus AS 1.3089]
MIEKIKEFVLSPDFVFSLIVVGFIIVVALLLLENRRDTRKLVQLNQKIKGLIAGDYSEVLDMQGSPEITDMTNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIITINDMATKQLGVKRDDVLNTSILDLLDIADEYDLRELITNVPE
LTIDSQDENGEYVSLRVRFALIRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALS
EPVAPEFVKVSLTETNRMMRMVTDLLSLSRIDNNTSHLDVELTNFTAFITYILNRFDKIKNQDETKKYEIIRDYSITPIW
VEIDTDKMTQVIDNIMNNAIKYSPDGGTITVSVRTTDVQLILSISDEGLGIPKQDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHHGFIWAKSEYGKGSTFTIVLPYDNDAVRVDDWENEENVESEHD

Nucleotide

• Length: 1365 bp

>NTDB_id=58450 I872_RS05705 WP_015605197.1 1145613..1146977(-) (micB) [Streptococcus cristatus AS 1.3089]
ATGATTGAAAAAATAAAAGAGTTTGTTCTGTCTCCTGACTTTGTCTTTTCACTGATCGTTGTCGGCTTTATCATCGTTGT
AGCCCTCTTGCTGCTGGAAAATCGACGGGATACTCGAAAACTGGTCCAATTAAATCAAAAGATTAAAGGCTTGATTGCAG
GAGATTATTCAGAAGTTTTAGATATGCAGGGAAGTCCTGAAATCACGGATATGACCAATTCTATCAATGATCTTTCTGAA
GTCATTCGCCTGACGCATGAAAATTTGGAGCAAGAGACCAAGCGTCTATCCAGCATCCTGTCTTACATGACGGATGGCGT
ACTTGCGACCAACCGTCGAGGACAGATTATCACTATCAATGACATGGCGACCAAGCAGCTGGGGGTCAAACGTGATGATG
TGCTTAATACTAGTATTTTAGATTTGCTGGATATTGCTGATGAGTACGATTTGCGCGAATTGATTACCAATGTTCCAGAA
TTGACCATTGATTCTCAAGATGAAAATGGCGAATACGTAAGCCTGCGGGTTCGGTTTGCCTTGATTAGACGGGAGTCAGG
TTTTATATCAGGGTTGGTAGCAGTGCTGCACGATACAACGGAGCAAGACAAGGAAGAACGGGAGCGTCGGCTTTTCGTTT
CCAATGTTAGCCATGAATTGCGGACGCCTCTAACCAGTGTAAAATCCTATCTGGAAGCCTTGGATGATGGTGCTCTGTCA
GAGCCTGTTGCACCGGAATTTGTCAAAGTTTCACTAACTGAGACAAACCGGATGATGCGGATGGTGACGGACTTACTTAG
CTTATCGCGGATTGATAATAATACCAGCCATCTGGACGTTGAGCTGACTAATTTTACGGCCTTTATCACCTATATCCTTA
ACCGTTTTGATAAGATTAAAAATCAGGATGAGACCAAAAAATATGAGATTATCAGGGATTATTCAATTACGCCGATTTGG
GTAGAGATTGATACGGATAAGATGACTCAGGTTATTGATAATATCATGAACAATGCCATCAAGTATTCACCTGATGGTGG
GACGATTACGGTTTCTGTGAGGACAACAGATGTTCAGTTGATTCTTTCGATTTCGGATGAAGGTTTGGGCATTCCCAAGC
AGGATCTGCCAAAGATTTTTGATCGTTTCTATCGGGTGGATAAGGCCCGCAGTCGAGCCCAGGGAGGAACGGGCTTGGGT
CTGGCTATTGCTAAAGAAATTATCAAGCAGCATCATGGCTTTATCTGGGCTAAGAGCGAGTACGGTAAGGGTTCTACCTT
TACCATCGTCCTTCCTTATGATAATGATGCTGTCCGTGTAGATGACTGGGAAAATGAAGAGAATGTAGAAAGTGAACATG
ACTAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

• PAS fold (PAS) (95-198)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	78.36	96.696	0.758
vicK	Streptococcus mutans UA159	71.393	88.546	0.632