Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   JGX27_RS06110 Genome accession   NZ_CP077423
Coordinates   1200944..1201618 (-) Length   224 a.a.
NCBI ID   WP_009854247.1    Uniprot ID   A0A139MP14
Organism   Streptococcus gallolyticus subsp. gallolyticus TX20005     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1195944..1206618
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JGX27_RS06085 (JGX27_06085) deoC 1196373..1197035 (-) 663 WP_009854243.1 deoxyribose-phosphate aldolase -
  JGX27_RS06090 (JGX27_06090) - 1197525..1198118 (-) 594 WP_009854244.1 class I SAM-dependent methyltransferase -
  JGX27_RS06095 (JGX27_06095) coaA 1198232..1199152 (+) 921 WP_009854245.1 type I pantothenate kinase -
  JGX27_RS06100 (JGX27_06100) rpsT 1199227..1199478 (+) 252 WP_003064878.1 30S ribosomal protein S20 -
  JGX27_RS06105 (JGX27_06105) ciaH 1199614..1200954 (-) 1341 WP_009854246.1 cell wall metabolism sensor histidine kinase WalK Regulator
  JGX27_RS06110 (JGX27_06110) ciaR 1200944..1201618 (-) 675 WP_009854247.1 response regulator transcription factor Regulator
  JGX27_RS06115 (JGX27_06115) - 1201816..1204359 (-) 2544 WP_009854248.1 M1 family metallopeptidase -
  JGX27_RS06120 (JGX27_06120) phoU 1204582..1205235 (-) 654 WP_009854249.1 phosphate signaling complex protein PhoU -
  JGX27_RS06125 (JGX27_06125) pstB 1205266..1206024 (-) 759 WP_009854250.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25465.13 Da        Isoelectric Point: 4.3102

>NTDB_id=581509 JGX27_RS06110 WP_009854247.1 1200944..1201618(-) (ciaR) [Streptococcus gallolyticus subsp. gallolyticus TX20005]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREKGVSTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKYNDNTLSYEELTVDTSTNTTIANGKEVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFAKNLQTLRSVGYILKNAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=581509 JGX27_RS06110 WP_009854247.1 1200944..1201618(-) (ciaR) [Streptococcus gallolyticus subsp. gallolyticus TX20005]
ATGATTAAGATATTATTAGTAGAAGATGATTTGAGTCTATCTAATTCCATTTTTGATTTTTTAGATGATTTTGCAGATGT
TATGCAGGTATTTGACGGCGAAGAAGGTTTGTACGAAGCTGAAAGTGGCGTATATGACCTTATTTTGCTTGACTTGATGT
TACCTGAAAAAGATGGTTTCCAAGTGCTTAAAGAGTTACGAGAAAAAGGTGTGTCAACACCAGTACTTATTATGACTGCC
AAAGAAAGCCTTGATGATAAGGGACATGGTTTCGAGTTGGGAGCAGATGATTACCTTACTAAACCATTTTACCTTGAAGA
GCTAAAAATGCGTATTCAAGCTCTTTTAAAACGTTCGGGTAAATACAACGACAATACCTTATCTTATGAAGAATTAACCG
TTGACACTTCTACCAATACAACAATAGCTAACGGTAAAGAAGTCGAGCTGCTTGGTAAAGAATTTGATTTGTTGGTTTAT
TTCTTACAAAATCAAAATGTTATTTTACCAAAATCACAAATTTTTGACCGTATTTGGGGCTTTGATAGTGATACAACGAT
TTCGGTTGTTGAAGTTTACGTTTCAAAAATTCGAAAAAAACTCAAAGGCACTACCTTTGCCAAAAATCTTCAAACCCTAC
GGAGTGTAGGTTATATTCTGAAAAATGCTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139MP14

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

92.825

99.554

0.924
  ciaR Streptococcus pneumoniae Rx1

87.054

100

0.871
  ciaR Streptococcus pneumoniae D39

87.054

100

0.871
  ciaR Streptococcus pneumoniae R6

87.054

100

0.871
  ciaR Streptococcus pneumoniae TIGR4

87.054

100

0.871
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.938

100

0.393
  vicR Streptococcus mutans UA159

35.47

100

0.371
  micA Streptococcus pneumoniae Cp1015

35.622

100

0.371