Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   JGX27_RS06105 Genome accession   NZ_CP077423
Coordinates   1199614..1200954 (-) Length   446 a.a.
NCBI ID   WP_009854246.1    Uniprot ID   A0A139QTN8
Organism   Streptococcus gallolyticus subsp. gallolyticus TX20005     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1194614..1205954
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JGX27_RS06080 (JGX27_06080) - 1195120..1196184 (-) 1065 WP_009854242.1 BMP family protein -
  JGX27_RS06085 (JGX27_06085) deoC 1196373..1197035 (-) 663 WP_009854243.1 deoxyribose-phosphate aldolase -
  JGX27_RS06090 (JGX27_06090) - 1197525..1198118 (-) 594 WP_009854244.1 class I SAM-dependent methyltransferase -
  JGX27_RS06095 (JGX27_06095) coaA 1198232..1199152 (+) 921 WP_009854245.1 type I pantothenate kinase -
  JGX27_RS06100 (JGX27_06100) rpsT 1199227..1199478 (+) 252 WP_003064878.1 30S ribosomal protein S20 -
  JGX27_RS06105 (JGX27_06105) ciaH 1199614..1200954 (-) 1341 WP_009854246.1 cell wall metabolism sensor histidine kinase WalK Regulator
  JGX27_RS06110 (JGX27_06110) ciaR 1200944..1201618 (-) 675 WP_009854247.1 response regulator transcription factor Regulator
  JGX27_RS06115 (JGX27_06115) - 1201816..1204359 (-) 2544 WP_009854248.1 M1 family metallopeptidase -
  JGX27_RS06120 (JGX27_06120) phoU 1204582..1205235 (-) 654 WP_009854249.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50097.86 Da        Isoelectric Point: 5.3673

>NTDB_id=581508 JGX27_RS06105 WP_009854246.1 1199614..1200954(-) (ciaH) [Streptococcus gallolyticus subsp. gallolyticus TX20005]
MLNKLQKKLSSGTFSHFFHFFAVFTGIFVIMTVIILQIMRYGLYSSVDTSLQNAADNANDYVVRTMERSDTLQSDDSSTD
TFSGGTSSSGKAKPSTGGVGLSNVSVLLYDEDGKILNALDAFVQFGTLSTTFDEDSVGEIKEQKITTIFGQTEKYHVLTV
KVSSSEYPSIKYATFLVSVRQLDEASERYVTITITVMVIFWIISVVASVYLANWTRKPIMESYEKQKSFVENASHELRTP
LAVLQNRLESLFRRPDATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEDIQPTTFNEIFENYDMIAEENG
KTFVGHNLAERPIKSDRTLLKQLMTILFDNAIKYTDDDGVIEFTVKTTDKQTILTVADNGPGISDADKVKIFDRFYRVDK
ARTRQKGGFGLGLSLAKQIVDVLKGDIQVKDNQPKGTIFEVRFNRH

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=581508 JGX27_RS06105 WP_009854246.1 1199614..1200954(-) (ciaH) [Streptococcus gallolyticus subsp. gallolyticus TX20005]
ATGCTGAATAAATTACAGAAAAAATTATCGTCAGGGACATTTTCACATTTCTTCCATTTCTTTGCTGTCTTTACGGGAAT
TTTTGTCATCATGACAGTTATCATTTTGCAGATTATGCGCTATGGTCTTTATTCCTCTGTTGATACGAGTTTGCAAAATG
CAGCAGACAATGCCAATGATTATGTCGTGCGAACTATGGAACGTAGCGATACTTTGCAATCGGATGATTCTTCTACGGAC
ACTTTTTCAGGAGGAACAAGTAGTTCTGGGAAAGCGAAACCTAGTACTGGCGGAGTTGGTCTAAGTAACGTTAGCGTTCT
TCTTTATGATGAAGACGGTAAAATCTTAAATGCTTTGGATGCTTTTGTTCAATTTGGAACGTTATCGACAACTTTTGATG
AAGATAGTGTCGGCGAAATCAAAGAACAGAAGATTACGACCATTTTTGGTCAAACCGAGAAATACCATGTGCTGACTGTA
AAAGTGAGTAGTAGCGAGTATCCTAGTATAAAATACGCTACTTTCCTTGTTAGCGTTCGTCAGTTAGATGAAGCTAGCGA
ACGATATGTAACAATTACGATCACTGTTATGGTTATTTTCTGGATTATTTCGGTCGTAGCAAGTGTTTATCTTGCCAATT
GGACAAGAAAACCAATTATGGAAAGCTATGAAAAACAAAAATCCTTTGTCGAAAATGCTAGTCATGAGTTGCGTACACCG
CTTGCTGTTTTGCAGAATCGTTTAGAAAGTCTCTTTAGGCGACCCGATGCTACAATTTTGGATAATAGTGAAAGTATTGC
CGCCAGTCTAGACGAAGTTCGAAATATGCGAATTTTGACCACAAATCTGCTGAATTTGGCACGTCGTGACGATGGTTTGA
AAGTTGAGTTGGAGGATATTCAACCAACGACTTTCAATGAAATCTTTGAAAATTACGATATGATTGCTGAAGAAAATGGC
AAGACATTTGTCGGACATAATTTGGCAGAGCGACCAATCAAATCAGATCGTACATTGTTAAAACAACTGATGACTATCTT
ATTTGATAATGCCATAAAATACACCGACGATGATGGTGTCATTGAATTTACCGTTAAAACAACAGACAAACAAACAATTC
TGACAGTTGCTGATAACGGCCCAGGGATTAGCGACGCTGATAAAGTTAAGATTTTTGACCGTTTTTATCGTGTGGATAAA
GCACGGACACGTCAAAAAGGTGGTTTTGGTCTAGGATTGTCACTTGCTAAGCAAATTGTTGACGTTTTAAAAGGCGATAT
TCAAGTCAAAGATAACCAACCAAAAGGAACTATTTTTGAAGTTCGTTTTAATCGTCATTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(227-292)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(336-443)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139QTN8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.368

99.327

0.59
  ciaH Streptococcus pneumoniae Rx1

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae D39

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae R6

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae TIGR4

51.467

99.327

0.511