Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   SPN994038_RS13300 Genome accession   NC_021026
Coordinates   482512..483000 (-) Length   162 a.a.
NCBI ID   WP_307774349.1    Uniprot ID   -
Organism   Streptococcus pneumoniae SPN994038     
Function   transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 475127..484671 482512..483000 within 0


Gene organization within MGE regions


Location: 475127..484671
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN994038_RS02545 (SPN994038_04710) - 475127..475414 (-) 288 WP_000777760.1 hypothetical protein -
  SPN994038_RS02550 (SPN994038_04720) - 475424..475834 (-) 411 WP_001278301.1 HIT family protein -
  SPN994038_RS02555 (SPN994038_04730) pptA 475902..476633 (+) 732 WP_000889923.1 ABC transporter ATP-binding protein Regulator
  SPN994038_RS02560 (SPN994038_04740) - 476630..477679 (+) 1050 WP_000653752.1 ABC transporter permease -
  SPN994038_RS02565 (SPN994038_04750) - 477847..478176 (-) 330 WP_000132570.1 hypothetical protein -
  SPN994038_RS02570 (SPN994038_04760) - 478452..478790 (+) 339 WP_000682119.1 LytTR family DNA-binding domain-containing protein -
  SPN994038_RS02575 (SPN994038_04770) comE/blpR 478795..479532 (+) 738 WP_001219127.1 response regulator transcription factor Regulator
  SPN994038_RS02580 (SPN994038_04780) - 479546..480886 (+) 1341 WP_001017622.1 sensor histidine kinase -
  SPN994038_RS02585 (SPN994038_04790) blpC 480928..481083 (-) 156 WP_000358813.1 quorum-sensing system pheromone BlpC -
  SPN994038_RS02590 (SPN994038_04800) - 481140..482501 (-) 1362 WP_001069092.1 bacteriocin secretion accessory protein -
  SPN994038_RS13300 comA/nlmT 482512..483000 (-) 489 WP_307774349.1 ATP-binding cassette domain-containing protein Regulator
  SPN994038_RS13305 comA/nlmT 482984..483424 (-) 441 WP_001808911.1 ATP-binding cassette domain-containing protein Regulator
  SPN994038_RS13310 comA/nlmT 483414..484139 (-) 726 WP_167750760.1 ABC transporter transmembrane domain-containing protein Regulator
  SPN994038_RS13315 (SPN994038_04820) comA/nlmT 484084..484671 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator

Sequence

Protein


Download         Length: 162 a.a.        Molecular weight: 18195.07 Da        Isoelectric Point: 7.0620

>NTDB_id=58144 SPN994038_RS13300 WP_307774349.1 482512..483000(-) (comA/nlmT) [Streptococcus pneumoniae SPN994038]
MRRHINYLPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARAL
LTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGIHQELMQAQGFYHHLF
NK

Nucleotide


Download         Length: 489 bp        

>NTDB_id=58144 SPN994038_RS13300 WP_307774349.1 482512..483000(-) (comA/nlmT) [Streptococcus pneumoniae SPN994038]
TTGCGCCGTCATATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGG
TAATCATATGATTAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTA
TGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTT
TTAACTAAATCTCCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAA
TCTTATGTCCCTAACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTG
TTCTTGACCAGGGGAAAATCATTGAAGTTGGTATCCACCAAGAGTTAATGCAAGCGCAAGGTTTCTACCATCATCTATTC
AATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(2-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.05

99.383

0.716
  comA Streptococcus gordonii str. Challis substr. CH1

70.37

100

0.704
  comA Streptococcus mitis NCTC 12261

68.519

100

0.685
  comA Streptococcus pneumoniae Rx1

68.519

100

0.685
  comA Streptococcus pneumoniae D39

68.519

100

0.685
  comA Streptococcus pneumoniae R6

68.519

100

0.685
  comA Streptococcus mitis SK321

67.901

100

0.679
  comA Streptococcus pneumoniae TIGR4

67.901

100

0.679
  rcrQ Streptococcus mutans UA159

40.645

95.679

0.389

Multiple sequence alignment