Detailed information NTG0580401

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: I6L86_RS07500
• Genome accession: NZ_CP077259
• Coordinates: 1546501..1547151 (+)
• Length: 216 a.a.
• NCBI ID: WP_000387351.1
• Uniprot ID: A0AAX2L5S7
• Organism: Streptococcus mitis strain FDAARGOS 1456
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1541501..1552151

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L86_RS07470 (I6L86_07470)	frr	1541749..1542306 (+)	558	WP_001262225.1	ribosome recycling factor	-
I6L86_RS07475 (I6L86_07475)	cvfB	1542366..1543220 (+)	855	WP_001095458.1	RNA-binding virulence regulatory protein CvfB	-
I6L86_RS07480 (I6L86_07480)	-	1543229..1543444 (+)	216	WP_001232083.1	YozE family protein	-
I6L86_RS07485 (I6L86_07485)	-	1543529..1544524 (+)	996	WP_000658173.1	PhoH family protein	-
I6L86_RS07490 (I6L86_07490)	ald	1544581..1545693 (-)	1113	WP_000904719.1	alanine dehydrogenase	-
I6L86_RS07495 (I6L86_07495)	-	1545865..1546434 (+)	570	WP_000443732.1	GNAT family N-acetyltransferase	-
I6L86_RS07500 (I6L86_07500)	comEA/celA/cilE	1546501..1547151 (+)	651	WP_000387351.1	helix-hairpin-helix domain-containing protein	Machinery gene
I6L86_RS07505 (I6L86_07505)	comEC/celB	1547135..1549375 (+)	2241	WP_000942409.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6L86_RS07510 (I6L86_07510)	infC	1549595..1550125 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
I6L86_RS07515 (I6L86_07515)	rpmI	1550158..1550358 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
I6L86_RS07520 (I6L86_07520)	rplT	1550410..1550769 (+)	360	WP_000124834.1	50S ribosomal protein L20	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23173.54 Da
• Isoelectric Point: 6.0746

>NTDB_id=580401 I6L86_RS07500 WP_000387351.1 1546501..1547151(+) (comEA/celA/cilE) [Streptococcus mitis strain FDAARGOS 1456]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVVAVSKDSVSEKEVKKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAASQQAGPGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=580401 I6L86_RS07500 WP_000387351.1 1546501..1547151(+) (comEA/celA/cilE) [Streptococcus mitis strain FDAARGOS 1456]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATTGTTATCTGTACTGGTCTGGGATTACTTGTCGGAGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTCAAGGAAACGAATTTGCAGGCAGAAGTTGTAGCAGTTTCCAAGGATT
CGGTATCCGAAAAGGAAGTAAAGAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTTAAATCGCCAGGGATTTATGATTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAACAAGCAGATAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGACGAGGCTCTGGTTTACGTCCCAACTAAGGGAG
AAGAAGCAGCTAGTCAGCAGGCAGGTCCTGGGACGGCTTCCTCAACGAGCAAGGAAAAGAAGGTCAATCTCAATAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAAGGACTGGGTGGCAAACGAGCTCAGGATATTATCGACCATCGTGAGGCAAATGG
GAAATTCAAGTCGGTTGATGAACTCAAGAAAGTCTCTGGCATTGGTGCCAAGACCATAGAAAAGTTAAAAGATTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (76-126)

• Helix-hairpin-helix motif (HHH_3) (151-214)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus mitis NCTC 12261	100	100	1
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	96.759	100	0.968
comEA/celA/cilE	Streptococcus pneumoniae Rx1	96.296	100	0.963
comEA/celA/cilE	Streptococcus pneumoniae D39	96.296	100	0.963
comEA/celA/cilE	Streptococcus pneumoniae R6	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis SK321	92.593	100	0.926
comEA	Lactococcus lactis subsp. cremoris KW2	40.889	100	0.426
comEA	Latilactobacillus sakei subsp. sakei 23K	34.335	100	0.37