Detailed information NTG0580402

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: I6L86_RS07505
• Genome accession: NZ_CP077259
• Coordinates: 1547135..1549375 (+)
• Length: 746 a.a.
• NCBI ID: WP_000942409.1
• Uniprot ID: -
• Organism: Streptococcus mitis strain FDAARGOS 1456
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1542135..1554375

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L86_RS07475 (I6L86_07475)	cvfB	1542366..1543220 (+)	855	WP_001095458.1	RNA-binding virulence regulatory protein CvfB	-
I6L86_RS07480 (I6L86_07480)	-	1543229..1543444 (+)	216	WP_001232083.1	YozE family protein	-
I6L86_RS07485 (I6L86_07485)	-	1543529..1544524 (+)	996	WP_000658173.1	PhoH family protein	-
I6L86_RS07490 (I6L86_07490)	ald	1544581..1545693 (-)	1113	WP_000904719.1	alanine dehydrogenase	-
I6L86_RS07495 (I6L86_07495)	-	1545865..1546434 (+)	570	WP_000443732.1	GNAT family N-acetyltransferase	-
I6L86_RS07500 (I6L86_07500)	comEA/celA/cilE	1546501..1547151 (+)	651	WP_000387351.1	helix-hairpin-helix domain-containing protein	Machinery gene
I6L86_RS07505 (I6L86_07505)	comEC/celB	1547135..1549375 (+)	2241	WP_000942409.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6L86_RS07510 (I6L86_07510)	infC	1549595..1550125 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
I6L86_RS07515 (I6L86_07515)	rpmI	1550158..1550358 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
I6L86_RS07520 (I6L86_07520)	rplT	1550410..1550769 (+)	360	WP_000124834.1	50S ribosomal protein L20	-
I6L86_RS07525 (I6L86_07525)	-	1550945..1552609 (+)	1665	WP_000635031.1	molecular chaperone HscC	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84460.75 Da
• Isoelectric Point: 9.5655

>NTDB_id=580402 I6L86_RS07505 WP_000942409.1 1547135..1549375(+) (comEC/celB) [Streptococcus mitis strain FDAARGOS 1456]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSSSYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFLFQNWQQSQASQN
LADSVERVRILPDTVKVNGDSLSFRGKSDGRIFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPDGQRNFGGFDYQAY
LKTQGIYQTLTIKRIQSLQKVSSWDIGENLSSLRRKTVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNGLYSSLGIIHL
FALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFALSFLHPVIQLNFIFEWLEGMIRFVSQVASRPLVFGQPNAWILILLLISLALVYDLRKNIKRLAVLSLLITGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKIILIDVGGKAESSKKIEKWQEKTTTSNAQRTLIPYLKSRGVSKIDQLILTNTDK
EYVGDLLEVTKAFHVGEILVSKGSLKQKQFVAELQATQTKVRSITAGENLSIFGSQLEVLSPRKIGDGGYEDSLVLYGKL
LDKYFLFTGNLEEKGEKELLKHYPDLKVDVLKAGQHGSKKSSSSDFLEKLKPEFTLISVGKNNRAKLPHQETLTRLETIN
SKVYRTDQHGAIRFKGWNSWKVETVG

Nucleotide

• Length: 2241 bp

>NTDB_id=580402 I6L86_RS07505 WP_000942409.1 1547135..1549375(+) (comEC/celB) [Streptococcus mitis strain FDAARGOS 1456]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTTAGTTTTCTGTTGCTTTGGCTTTACTACGCCATTTT
CTCATCATCTTATCTCGCACTACTAGGTTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGTGGAATCTTTGGTTTCTGGTTTCTGTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
TTGGCGGATTCTGTTGAAAGGGTACGGATTTTACCAGACACTGTTAAGGTCAATGGTGATAGTCTATCCTTTCGTGGTAA
GTCTGATGGACGCATTTTTCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TTCATGAGATAGGACTAGAAGGAAAACTTTCAGAACCAGACGGGCAGAGAAATTTTGGTGGTTTTGACTACCAAGCCTAT
CTGAAAACTCAAGGGATTTACCAAACATTAACTATCAAAAGAATCCAGTCACTTCAAAAGGTTAGCAGTTGGGATATAGG
AGAAAATCTGTCCAGTTTACGTCGAAAGACTGTGGTTTGGATTAAGACGCATTTTCCAGACCCTATGCGCAATTACATGA
CAGGGCTCTTGTTAGGACATCTGGACACCGACTTTGAGGAGATGAACGGGCTTTATTCTAGTTTAGGAATTATCCACCTC
TTTGCCTTGTCGGGTATGCAGGTAGGTTTTTTCATGGACGGATTTAAGAAACTCCTCTTGCGATTGGGCTTGACTCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCAGGGCTGACAGGATTTTCAGCATCAGTTATTCGCAGTC
TTTTGCAAAAGTTACTGGCACAACATGGTGTTAAGGGCTTGGATAATTTTGCCTTGACGGTCCTTGTCCTCTTTATCGTC
ATGCCCAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCTTGACCATGACCAGCAAAGAAGG
AGAAGGCCTCAAGGCTGTTGCTAGAGAAAGTCTAGTCATTTCCTTGGGAATATTACCCATCCTATCCTTCTATTTTGCAG
AATTTCAGCCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTTTTTGACTTGGTCTTCTTACCGCTCTTGTCTATC
TTATTTGCCCTTTCCTTTCTTCATCCAGTCATTCAGCTGAATTTTATTTTTGAATGGTTGGAGGGAATGATTCGCTTTGT
ATCACAGGTGGCAAGTAGACCTCTGGTCTTTGGACAACCCAATGCATGGATTTTAATCTTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAAGGCTAGCAGTGTTGAGCTTATTGATTACAGGTCTCTTTTTCTTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTTGGGCAAGGGGAAAGTATTTTCCTACGGGATGTAACTGGTAAAAT
CATTCTCATAGATGTGGGTGGCAAGGCAGAGTCTAGTAAGAAAATAGAAAAATGGCAAGAAAAGACGACGACCAGTAATG
CCCAGCGAACCTTGATACCCTATCTCAAAAGTCGCGGAGTATCCAAGATTGACCAGCTAATTTTGACCAATACGGACAAG
GAATATGTTGGAGATTTGTTGGAGGTGACCAAGGCTTTTCATGTAGGCGAAATTTTAGTGTCAAAAGGCAGTTTGAAACA
GAAGCAATTTGTGGCAGAACTACAAGCGACCCAAACAAAAGTTAGAAGTATAACAGCAGGAGAGAACTTGTCAATTTTTG
GAAGTCAGTTAGAAGTCCTATCTCCAAGGAAAATTGGAGATGGAGGTTATGAAGATTCCCTGGTTCTGTATGGAAAACTT
TTGGATAAGTACTTTCTCTTCACAGGAAATTTGGAGGAAAAAGGAGAGAAGGAATTGCTGAAGCACTATCCAGACTTGAA
AGTGGATGTTTTAAAAGCTGGCCAACATGGCTCTAAAAAATCATCAAGTTCAGACTTTCTAGAAAAACTCAAACCAGAGT
TTACTCTTATCTCAGTTGGAAAGAACAATCGAGCGAAACTCCCCCATCAGGAAACTTTGACACGACTGGAAACTATCAAT
AGTAAAGTTTACCGAACTGACCAGCATGGAGCTATACGCTTTAAAGGGTGGAATAGTTGGAAAGTCGAAACGGTTGGTTA
A

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-693)

• Domain of unknown function (DUF4131) (DUF4131) (29-176)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	100	100	1
comEC/celB	Streptococcus mitis SK321	91.946	99.866	0.918
comEC/celB	Streptococcus pneumoniae TIGR4	91.812	99.866	0.917
comEC/celB	Streptococcus pneumoniae D39	91.544	99.866	0.914
comEC/celB	Streptococcus pneumoniae Rx1	91.544	99.866	0.914
comEC/celB	Streptococcus pneumoniae R6	91.544	99.866	0.914
comEC	Lactococcus lactis subsp. cremoris KW2	44.459	99.196	0.441