Detailed information NTG0580332

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: I6L86_RS00475
• Genome accession: NZ_CP077259
• Coordinates: 90689..91279 (-)
• Length: 196 a.a.
• NCBI ID: WP_000613475.1
• Uniprot ID: F9HD24
• Organism: Streptococcus mitis strain FDAARGOS 1456
• Function: degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 85689..96279

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L86_RS00450 (I6L86_00450)	-	86387..87151 (-)	765	WP_001185997.1	ABC transporter ATP-binding protein	-
I6L86_RS00455 (I6L86_00455)	-	87151..88107 (-)	957	WP_000662290.1	branched-chain amino acid ABC transporter permease	-
I6L86_RS00460 (I6L86_00460)	-	88111..88980 (-)	870	WP_000941427.1	branched-chain amino acid ABC transporter permease	-
I6L86_RS00465 (I6L86_00465)	-	89097..90257 (-)	1161	WP_000726117.1	ABC transporter substrate-binding protein	-
I6L86_RS00470 (I6L86_00470)	-	90335..90610 (-)	276	WP_000462122.1	YlbG family protein	-
I6L86_RS00475 (I6L86_00475)	clpP	90689..91279 (-)	591	WP_000613475.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
I6L86_RS00480 (I6L86_00480)	upp	91452..92081 (-)	630	WP_000515974.1	uracil phosphoribosyltransferase	-
I6L86_RS00485 (I6L86_00485)	-	92170..92637 (-)	468	WP_000136976.1	deoxycytidylate deaminase	-
I6L86_RS00490 (I6L86_00490)	-	92656..93213 (-)	558	WP_000004136.1	TetR/AcrR family transcriptional regulator	-
I6L86_RS00495 (I6L86_00495)	-	93338..94183 (+)	846	WP_078228468.1	DegV family protein	-
I6L86_RS00500 (I6L86_00500)	-	94242..95414 (+)	1173	WP_078228466.1	NAD(P)/FAD-dependent oxidoreductase	-
I6L86_RS00505 (I6L86_00505)	-	95463..95984 (+)	522	WP_061864256.1	DUF1697 domain-containing protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21340.32 Da
• Isoelectric Point: 4.4910

>NTDB_id=580332 I6L86_RS00475 WP_000613475.1 90689..91279(-) (clpP) [Streptococcus mitis strain FDAARGOS 1456]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SIEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN

Nucleotide

• Length: 591 bp

>NTDB_id=580332 I6L86_RS00475 WP_000613475.1 90689..91279(-) (clpP) [Streptococcus mitis strain FDAARGOS 1456]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGCCCAGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTAGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCTGGTGGTTCCGTTTCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATCAAGGCCGATGTCCAAACCATTGTTATGGGAATGGCAGCATCTATGGGGACGGTCATTGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCAGAGTATATGATCCACCAACCAATGGGTGGTACAGGTGGAGGTACTCAGCAAA
CCGATATGGCGATCGCTGCAGAACACTTGCTTAAAACTCGTAATACTTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATCGAAAAAGTCCATGCAGATGCAGAACGAGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCCAACAATTCATTGAATTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: F9HD24

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pneumoniae Rx1	99.49	100	0.995
clpP	Streptococcus pneumoniae D39	99.49	100	0.995
clpP	Streptococcus pneumoniae R6	99.49	100	0.995
clpP	Streptococcus pneumoniae TIGR4	99.49	100	0.995
clpP	Streptococcus thermophilus LMG 18311	93.333	99.49	0.929
clpP	Streptococcus thermophilus LMD-9	93.333	99.49	0.929
clpP	Streptococcus pyogenes JRS4	91.282	99.49	0.908
clpP	Streptococcus pyogenes MGAS315	91.282	99.49	0.908
clpP	Streptococcus mutans UA159	86.224	100	0.862
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	85.128	99.49	0.847
clpP	Lactococcus lactis subsp. cremoris KW2	84.615	99.49	0.842
clpP	Bacillus subtilis subsp. subtilis str. 168	58.854	97.959	0.577
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571