Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   I6L85_RS06870 Genome accession   NZ_CP077248
Coordinates   1387448..1388149 (-) Length   233 a.a.
NCBI ID   WP_008809004.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS 1455     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1382448..1393149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L85_RS06850 (I6L85_06850) rnc 1383966..1384664 (-) 699 WP_061601751.1 ribonuclease III -
  I6L85_RS06855 (I6L85_06855) - 1384907..1385263 (-) 357 WP_008809001.1 YbaN family protein -
  I6L85_RS06860 (I6L85_06860) vicX 1385298..1386101 (-) 804 WP_045634630.1 MBL fold metallo-hydrolase Regulator
  I6L85_RS06865 (I6L85_06865) micB 1386094..1387455 (-) 1362 WP_111723481.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6L85_RS06870 (I6L85_06870) micA 1387448..1388149 (-) 702 WP_008809004.1 response regulator YycF Regulator
  I6L85_RS06875 (I6L85_06875) - 1388549..1388926 (-) 378 WP_002899930.1 carboxymuconolactone decarboxylase family protein -
  I6L85_RS06880 (I6L85_06880) - 1389004..1389366 (+) 363 WP_111723480.1 MerR family transcriptional regulator -
  I6L85_RS06885 (I6L85_06885) thrS 1389421..1391364 (-) 1944 WP_111723479.1 threonine--tRNA ligase -
  I6L85_RS10595 - 1391456..1391827 (-) 372 WP_111724283.1 hypothetical protein -
  I6L85_RS06890 (I6L85_06890) - 1392161..1392523 (-) 363 WP_111723478.1 hypothetical protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26790.54 Da        Isoelectric Point: 4.6297

>NTDB_id=580279 I6L85_RS06870 WP_008809004.1 1387448..1388149(-) (micA) [Streptococcus gordonii strain FDAARGOS 1455]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAENPDILILDLMLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKAILRRSEFAVDTQESEKGSNELTVGELQILPDAFVAKKHGEELELTH
REFELLYHLASHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=580279 I6L85_RS06870 WP_008809004.1 1387448..1388149(-) (micA) [Streptococcus gordonii strain FDAARGOS 1455]
ATGAAGAAAATATTAGTTGTAGATGATGAAAAACCAATTTCAGATATTATAAAATTTAATATGGTAAAAGAGGGCTATGA
AGTTGTTACGGCTTTTGATGGTCGTGAAGCTCTTGAGATGTTTGAAGCTGAAAATCCTGATATTTTGATTTTGGATTTGA
TGTTGCCAGAGTTGGACGGGCTAGAAGTAGCACGCACCATTCGGAAGACCAGTAATGTTCCAATTATTGTCCTATCGGCT
AAAGATAGTGAGTTTGATAAAGTTATCGGCCTTGAGATCGGAGCAGACGACTATGTGACCAAGCCTTTCTCTAACCGTGA
GCTCCAAGCTCGTGTCAAGGCTATTTTGCGACGTTCAGAATTTGCTGTAGATACCCAAGAAAGTGAAAAGGGCTCAAATG
AGTTGACAGTGGGTGAATTGCAAATTTTACCCGATGCTTTTGTTGCCAAGAAACATGGTGAAGAGCTAGAATTAACCCAT
CGTGAGTTTGAATTACTCTACCATTTGGCTAGTCATGTTGGTCAAGTAATGACACGCGAACACCTACTAGAGACAGTTTG
GGGTTATGATTATTTTGGTGATGTACGCACTGTTGATGTGACGATTCGCCGTCTACGTGAAAAGATTGAAGATACGCCAA
GCCGACCAGAGTATATTTTAACTCGTCGTGGTGTTGGCTATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

84.12

100

0.841
  vicR Streptococcus mutans UA159

79.574

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  covR Streptococcus salivarius strain HSISS4

44.105

98.283

0.433
  scnR Streptococcus mutans UA159

37.5

99.571

0.373