Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   SPN994039_RS10725 Genome accession   NC_021005
Coordinates   1993347..1994009 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae SPN994039     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1988347..1999009
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN994039_RS10700 (SPN994039_19370) - 1988497..1988763 (-) 267 WP_001278167.1 Veg family protein -
  SPN994039_RS10705 (SPN994039_19380) dnaB 1988765..1990117 (-) 1353 WP_000852486.1 replicative DNA helicase -
  SPN994039_RS10710 (SPN994039_19390) rplI 1990161..1990613 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  SPN994039_RS10715 (SPN994039_19400) - 1990610..1992583 (-) 1974 WP_000715124.1 DHH family phosphoesterase -
  SPN994039_RS10720 (SPN994039_19410) raiA 1992719..1993267 (-) 549 WP_000599107.1 ribosome-associated translation inhibitor RaiA -
  SPN994039_RS10725 (SPN994039_19420) comFC/cflB 1993347..1994009 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  SPN994039_RS10730 (SPN994039_19430) comFA/cflA 1994006..1995304 (-) 1299 WP_000867612.1 DEAD/DEAH box helicase Machinery gene
  SPN994039_RS10735 (SPN994039_19440) - 1995360..1995995 (+) 636 WP_000395739.1 YigZ family protein -
  SPN994039_RS10740 (SPN994039_19450) cysK 1996280..1997200 (+) 921 WP_000029867.1 cysteine synthase A -
  SPN994039_RS10745 (SPN994039_19460) - 1997439..1997804 (-) 366 Protein_2027 IS66 family transposase -
  SPN994039_RS10750 (SPN994039_19470) - 1997786..1998073 (+) 288 Protein_2028 transposase -
  SPN994039_RS10755 (SPN994039_19480) tnpB 1998228..1998551 (-) 324 WP_000973415.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=57982 SPN994039_RS10725 WP_000649971.1 1993347..1994009(-) (comFC/cflB) [Streptococcus pneumoniae SPN994039]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=57982 SPN994039_RS10725 WP_000649971.1 1993347..1994009(-) (comFC/cflB) [Streptococcus pneumoniae SPN994039]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAACAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914

Multiple sequence alignment