Detailed information NTG0057951

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: SPN994039_RS08550
• Genome accession: NC_021005
• Coordinates: 1603215..1603874 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565024.1
• Uniprot ID: A0A4J1XTA1
• Organism: Streptococcus pneumoniae SPN994039
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1598215..1608874

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPN994039_RS08525 (SPN994039_15780)	-	1598520..1598837 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
SPN994039_RS08530 (SPN994039_15790)	-	1598852..1599748 (-)	897	WP_000825665.1	PEP phosphonomutase	-
SPN994039_RS08535 (SPN994039_15800)	-	1599751..1601013 (-)	1263	WP_000413345.1	PTS sugar transporter subunit IIC	-
SPN994039_RS08540 (SPN994039_15810)	-	1601293..1602471 (+)	1179	WP_000175878.1	ROK family transcriptional regulator	-
SPN994039_RS08545 (SPN994039_15820)	-	1602699..1603145 (-)	447	WP_000155412.1	GNAT family N-acetyltransferase	-
SPN994039_RS08550 (SPN994039_15830)	cclA/cilC	1603215..1603874 (+)	660	WP_000565024.1	A24 family peptidase	Machinery gene
SPN994039_RS08555 (SPN994039_15840)	-	1603926..1605077 (-)	1152	WP_000481758.1	XRE family transcriptional regulator	-
SPN994039_RS08560 (SPN994039_15850)	-	1605092..1605823 (-)	732	WP_000934017.1	hypothetical protein	-
SPN994039_RS12725	-	1606052..1606153 (+)	102	Protein_1653	prepilin peptidase	-
SPN994039_RS08565 (SPN994039_15860)	trpA	1606125..1606901 (-)	777	WP_001127028.1	tryptophan synthase subunit alpha	-
SPN994039_RS08570 (SPN994039_15870)	trpB	1606894..1608117 (-)	1224	WP_000331297.1	tryptophan synthase subunit beta	-
SPN994039_RS08575 (SPN994039_15880)	-	1608095..1608694 (-)	600	WP_000169899.1	phosphoribosylanthranilate isomerase	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24951.16 Da
• Isoelectric Point: 8.2409

>NTDB_id=57951 SPN994039_RS08550 WP_000565024.1 1603215..1603874(+) (cclA/cilC) [Streptococcus pneumoniae SPN994039]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWKLLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILITSSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=57951 SPN994039_RS08550 WP_000565024.1 1603215..1603874(+) (cclA/cilC) [Streptococcus pneumoniae SPN994039]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGAAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAACTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTATCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

3D structure

• AlphaFold DB: A0A4J1XTA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	96.804	100	0.968
cclA/cilC	Streptococcus pneumoniae Rx1	95.434	100	0.954
cclA/cilC	Streptococcus pneumoniae D39	95.434	100	0.954
cclA/cilC	Streptococcus pneumoniae R6	95.434	100	0.954
cclA/cilC	Streptococcus mitis SK321	91.324	100	0.913
cclA/cilC	Streptococcus mitis NCTC 12261	85.388	100	0.854