Detailed information NTG0577805

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: MTP23_RS02425
• Genome accession: NZ_CP094443
• Coordinates: 452348..452659 (+)
• Length: 103 a.a.
• NCBI ID: WP_000472256.1
• Uniprot ID: A0A0H2XGS7
• Organism: Staphylococcus aureus strain N10CSA27
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 447348..457659

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MTP23_RS02395 (MTP23_02395)	-	448131..448334 (+)	204	WP_000087561.1	YqgQ family protein	-
MTP23_RS02400 (MTP23_02400)	-	448331..449317 (+)	987	WP_000161311.1	ROK family glucokinase	-
MTP23_RS02405 (MTP23_02405)	-	449317..449646 (+)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
MTP23_RS02410 (MTP23_02410)	-	449643..450266 (+)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
MTP23_RS02415 (MTP23_02415)	comGA	450318..451292 (+)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
MTP23_RS02420 (MTP23_02420)	comGB	451264..452334 (+)	1071	WP_000776422.1	competence type IV pilus assembly protein ComGB	Machinery gene
MTP23_RS02425 (MTP23_02425)	comGC	452348..452659 (+)	312	WP_000472256.1	competence type IV pilus major pilin ComGC	Machinery gene
MTP23_RS02430 (MTP23_02430)	comGD	452637..453083 (+)	447	WP_001788899.1	competence type IV pilus minor pilin ComGD	Machinery gene
MTP23_RS02435 (MTP23_02435)	comGE	453070..453369 (+)	300	WP_000844410.1	hypothetical protein	Machinery gene
MTP23_RS02440 (MTP23_02440)	comGF	453287..453784 (+)	498	WP_001788897.1	competence type IV pilus minor pilin ComGF	Machinery gene
MTP23_RS02445 (MTP23_02445)	-	453881..454027 (+)	147	WP_001792109.1	hypothetical protein	-
MTP23_RS02450 (MTP23_02450)	-	454017..454541 (+)	525	WP_001015120.1	shikimate kinase	-
MTP23_RS02455 (MTP23_02455)	gcvT	454700..455791 (+)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-
MTP23_RS02460 (MTP23_02460)	gcvPA	455811..457157 (+)	1347	WP_000019691.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-

Sequence

Protein

• Length: 103 a.a.
• Molecular weight: 11315.36 Da
• Isoelectric Point: 8.5268

>NTDB_id=577805 MTP23_RS02425 WP_000472256.1 452348..452659(+) (comGC) [Staphylococcus aureus strain N10CSA27]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGETITISNGEAVAN

Nucleotide

• Length: 312 bp

>NTDB_id=577805 MTP23_RS02425 WP_000472256.1 452348..452659(+) (comGC) [Staphylococcus aureus strain N10CSA27]
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGACAATAACAATTAGTAATGGAGAAGCAGTTGCAAATTAG

Domains

Predicted by InterProScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (6-30)

3D structure

• AlphaFold DB: A0A0H2XGS7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Staphylococcus aureus MW2	100	100	1
comGC	Staphylococcus aureus N315	100	100	1
comGC/cglC	Streptococcus pneumoniae TIGR4	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae Rx1	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae D39	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae R6	46.078	99.029	0.456
comGC/cglC	Streptococcus mitis SK321	51.163	83.495	0.427
comGC/cglC	Streptococcus mitis NCTC 12261	51.163	83.495	0.427
comGC	Streptococcus gordonii str. Challis substr. CH1	42.857	95.146	0.408
comGC	Streptococcus suis isolate S10	50	75.728	0.379
comGC	Bacillus subtilis subsp. subtilis str. 168	41.758	88.35	0.369
comGC	Lactococcus lactis subsp. cremoris KW2	46.341	79.612	0.369