Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   KQ224_RS03310 Genome accession   NZ_CP076721
Coordinates   654237..654941 (-) Length   234 a.a.
NCBI ID   WP_174845892.1    Uniprot ID   -
Organism   Streptococcus parasuis strain H35     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 649237..659941
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQ224_RS03295 (KQ224_03295) pbp2b 649732..651807 (-) 2076 WP_301553947.1 penicillin-binding protein PBP2B -
  KQ224_RS03300 (KQ224_03300) vicX 652085..652888 (-) 804 WP_216807038.1 MBL fold metallo-hydrolase Regulator
  KQ224_RS03305 (KQ224_03305) micB 652895..654244 (-) 1350 WP_174845893.1 cell wall metabolism sensor histidine kinase VicK Regulator
  KQ224_RS03310 (KQ224_03310) micA 654237..654941 (-) 705 WP_174845892.1 response regulator YycF Regulator
  KQ224_RS03315 (KQ224_03315) - 655141..655902 (+) 762 WP_024391259.1 amino acid ABC transporter ATP-binding protein -
  KQ224_RS03320 (KQ224_03320) - 655912..656751 (+) 840 WP_216807039.1 transporter substrate-binding domain-containing protein -
  KQ224_RS03325 (KQ224_03325) - 656768..657466 (+) 699 WP_216807040.1 amino acid ABC transporter permease -
  KQ224_RS03330 (KQ224_03330) - 657481..658140 (+) 660 WP_171988525.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26799.79 Da        Isoelectric Point: 4.7428

>NTDB_id=577566 KQ224_RS03310 WP_174845892.1 654237..654941(-) (micA) [Streptococcus parasuis strain H35]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALDIFEAEFPDIVILDLMLPEIDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQEAVESSGTPELVIGDLVIVPDAFVAKKHGKELELT
HREFELLYHLAKHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYFIKAYD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=577566 KQ224_RS03310 WP_174845892.1 654237..654941(-) (micA) [Streptococcus parasuis strain H35]
ATGAAGAAAATTTTAATTGTTGATGATGAGAAACCAATCTCGGATATTATTAAGTTCAATATGACACGTGAAGGATATGA
GGTAGTTACTGCGTTTGATGGACGTGAGGCGCTTGATATTTTTGAAGCAGAGTTTCCAGACATTGTTATTTTAGATTTAA
TGCTTCCAGAAATAGATGGATTAGAAGTAGCACGGACGATTCGAAAAACAAGTAATGTTCCTATTTTAATGTTGTCAGCT
AAAGATAGTGAGTTTGATAAAGTTATTGGGCTTGAAATTGGTGCGGATGACTATGTGACAAAGCCATTCTCAAACCGTGA
ATTACAGGCGCGTGTAAAAGCTCTTCTTCGTCGAAGTGAATTGGCTGAGACGCAAGAAGCAGTTGAATCATCTGGTACTC
CAGAATTGGTAATCGGTGATTTGGTAATTGTTCCAGATGCTTTTGTAGCTAAGAAACATGGAAAAGAACTTGAACTAACA
CACCGTGAATTTGAATTATTGTATCATTTGGCCAAGCACATTGGACAAGTCATGACGCGAGAGCATCTACTTGAGACTGT
TTGGGGATATGATTATTTTGGAGATGTACGTACTGTGGACGTGACGGTTCGACGCTTGCGTGAAAAAATTGAAGACACTC
CAAGTCGTCCGGAATACATCTTGACACGCAGGGGAGTAGGTTATTTTATAAAAGCTTATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

83.983

98.718

0.829
  vicR Streptococcus mutans UA159

80.851

100

0.812
  covR Streptococcus salivarius strain HSISS4

43.29

98.718

0.427
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.478

98.291

0.427
  scnR Streptococcus mutans UA159

36.709

100

0.372