Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   KQ224_RS03305 Genome accession   NZ_CP076721
Coordinates   652895..654244 (-) Length   449 a.a.
NCBI ID   WP_174845893.1    Uniprot ID   -
Organism   Streptococcus parasuis strain H35     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 647895..659244
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQ224_RS03285 (KQ224_03285) - 647972..649018 (-) 1047 WP_216807035.1 D-alanine--D-alanine ligase -
  KQ224_RS03290 (KQ224_03290) recR 649127..649723 (-) 597 WP_216807036.1 recombination mediator RecR -
  KQ224_RS03295 (KQ224_03295) pbp2b 649732..651807 (-) 2076 WP_301553947.1 penicillin-binding protein PBP2B -
  KQ224_RS03300 (KQ224_03300) vicX 652085..652888 (-) 804 WP_216807038.1 MBL fold metallo-hydrolase Regulator
  KQ224_RS03305 (KQ224_03305) micB 652895..654244 (-) 1350 WP_174845893.1 cell wall metabolism sensor histidine kinase VicK Regulator
  KQ224_RS03310 (KQ224_03310) micA 654237..654941 (-) 705 WP_174845892.1 response regulator YycF Regulator
  KQ224_RS03315 (KQ224_03315) - 655141..655902 (+) 762 WP_024391259.1 amino acid ABC transporter ATP-binding protein -
  KQ224_RS03320 (KQ224_03320) - 655912..656751 (+) 840 WP_216807039.1 transporter substrate-binding domain-containing protein -
  KQ224_RS03325 (KQ224_03325) - 656768..657466 (+) 699 WP_216807040.1 amino acid ABC transporter permease -
  KQ224_RS03330 (KQ224_03330) - 657481..658140 (+) 660 WP_171988525.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51051.41 Da        Isoelectric Point: 4.5989

>NTDB_id=577565 KQ224_RS03305 WP_174845893.1 652895..654244(-) (micB) [Streptococcus parasuis strain H35]
MINQLRYLITTAEFWFVVILVGFLIALTVLLIENYRDNKQIQLLNKKVGALIDGNYSDVLDLRGSPEITEMANSLNDLSE
VIRLTHDHLEQEKIRLSSILSYMSDGVIATDRIGRIIMVNDMAQKQLGLKDHKQEQYFLLDVLELQDQYSLRELLSQTPE
IVLEKVNENQELLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGEMDVELINFTAFITFILNRFDQMRNSDVGKTYAIIRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGNITFSMKTTDSQLILSISDEGLGIPKADLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWEEVAEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=577565 KQ224_RS03305 WP_174845893.1 652895..654244(-) (micB) [Streptococcus parasuis strain H35]
ATGATTAATCAATTACGCTATCTAATTACAACAGCTGAATTTTGGTTTGTTGTTATTTTGGTGGGCTTTCTAATTGCGTT
GACAGTATTGTTGATAGAAAACTATCGTGACAATAAGCAGATTCAATTACTCAATAAAAAAGTTGGCGCCTTGATAGATG
GTAATTACTCTGATGTATTGGATTTGCGAGGAAGTCCAGAGATTACTGAAATGGCAAATTCACTGAATGATTTGTCAGAA
GTAATCCGTTTAACGCACGATCACCTAGAACAAGAAAAAATCCGGCTCAGTTCCATTCTTTCCTACATGAGTGATGGAGT
CATTGCTACAGATCGTATTGGCCGAATTATCATGGTCAATGATATGGCGCAGAAACAACTGGGGTTAAAAGATCATAAAC
AGGAGCAATATTTTTTACTTGATGTTCTAGAACTTCAAGACCAATATAGTCTGCGTGAGTTGTTATCTCAAACACCTGAA
ATCGTCTTAGAAAAAGTTAATGAGAATCAAGAATTACTGACCTTACGAGCTAATTTTGCAACGATTAGGAGTGAAAGTGG
GCTCATATCAGGGTTGGTTGTTGTCCTACATGATATGACGGAGCAGGCCAAGGAGGAACGTGAGCGCAGACTGTTTGTTT
CTAATGTCAGTCACGAATTGCGTACACCGTTGACCTCGGTTAAATCATATTTGGAAGCCTTGGATGAGGGAGCTCTGACC
GAATCGGTTGCCCCAAGTTTTGTCAAGGTATCCTTAGATGAAACCAACCGGATGATGCGGATGATTACAGATCTTTTAAG
TTTATCTCGCATTGATAATCAGGTTGGAGAGATGGATGTAGAGTTAATCAATTTTACAGCCTTTATCACTTTTATCTTGA
ATCGCTTTGATCAGATGAGGAATTCTGATGTTGGTAAGACCTACGCTATTATTCGTGATTACCAGATTAGTCCAATTTGG
GTTGAAATTGATACCGATAAGATGACGCAGGTACTGGATAATATTTTGAATAATGCTATCAAGTATTCTCCAGATGGGGG
AAACATTACCTTTAGTATGAAAACGACAGATAGTCAGCTTATTCTTTCTATTTCAGATGAGGGTTTGGGAATTCCTAAAG
CTGATTTACCTAAAATATTTGACCGTTTCTATCGAGTTGATAAAGCGCGTTCGAGAGCCCAAGGAGGCACAGGTTTAGGT
TTGGCGATTGCAAAAGAGATTGTAAAGCAACACAAAGGTTTCATTTGGGCTAAAAGTGAGTATGGACATGGTTCGACATT
TACGATTGTCTTACCATATAGTAAGGATATTGCACTGGATGAGTGGGAAGAGGTTGCTGAGGAAGAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

68.807

97.105

0.668
  vicK Streptococcus mutans UA159

69.479

89.755

0.624