Detailed information NTG0577474

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: KRG72_RS07210
• Genome accession: NZ_CP076703
• Coordinates: 1449111..1449701 (-)
• Length: 196 a.a.
• NCBI ID: WP_039696423.1
• Uniprot ID: A0A091BS49
• Organism: Streptococcus equinus strain S1
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1444111..1454701

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KRG72_RS07180 (KRG72_07190)	-	1444370..1445134 (-)	765	WP_074564246.1	ABC transporter ATP-binding protein	-
KRG72_RS07185 (KRG72_07195)	-	1445134..1446087 (-)	954	WP_258250349.1	branched-chain amino acid ABC transporter permease	-
KRG72_RS07190 (KRG72_07200)	-	1446091..1446975 (-)	885	WP_258250350.1	branched-chain amino acid ABC transporter permease	-
KRG72_RS07195 (KRG72_07205)	-	1447028..1448209 (-)	1182	WP_258250351.1	ABC transporter substrate-binding protein	-
KRG72_RS07200 (KRG72_07210)	-	1448324..1448575 (-)	252	WP_258250352.1	DUF2129 domain-containing protein	-
KRG72_RS07205 (KRG72_07215)	-	1448568..1449008 (-)	441	WP_258250353.1	YlbF family regulator	-
KRG72_RS07210 (KRG72_07220)	clpP	1449111..1449701 (-)	591	WP_039696423.1	ATP-dependent Clp protease proteolytic subunit	Regulator
KRG72_RS07215 (KRG72_07225)	-	1449830..1450723 (-)	894	WP_258250354.1	DMT family transporter	-
KRG72_RS07220 (KRG72_07230)	-	1450837..1451706 (+)	870	WP_258250355.1	LysR family transcriptional regulator	-
KRG72_RS07225 (KRG72_07235)	upp	1451776..1452405 (-)	630	WP_021142946.1	uracil phosphoribosyltransferase	-
KRG72_RS07230 (KRG72_07240)	-	1452555..1453718 (-)	1164	WP_258250356.1	MalY/PatB family protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21510.45 Da
• Isoelectric Point: 4.3383

>NTDB_id=577474 KRG72_RS07210 WP_039696423.1 1449111..1449701(-) (clpP) [Streptococcus equinus strain S1]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQSDMAIAAEHLLKTRQNLEQILADNSGQ
SLEKVHADAERDNWMSAQETLEYGFIDEIMVNNELN

Nucleotide

• Length: 591 bp

>NTDB_id=577474 KRG72_RS07210 WP_039696423.1 1449111..1449701(-) (clpP) [Streptococcus equinus strain S1]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGCGGTGAACGCTCATATGATATTTACTCACGTCTTTTGAAAGATCGTAT
CATTATGCTGACTGGACCAGTTGAAGACAATATGGCAAATTCTATTATTGCTCAACTATTGTTCCTTGATGCACAAGATA
ATACAAAAGATATTTACCTTTATGTTAATACACCTGGTGGATCAGTTTCAGCTGGTCTTGCTATTGTAGATACAATGAAC
TTCATTAAATCAGATGTTCAAACTATCGTTATGGGTATGGCAGCATCAATGGGAACAATCATTGCTTCATCAGGTACAAA
AGGTAAACGATTCATGTTGCCAAACGCTGAATATATGATTCACCAACCAATGGGTGGTACTGGTGGCGGTACTCAACAAA
GCGATATGGCTATTGCTGCTGAACACCTTTTGAAAACACGTCAAAACTTGGAACAAATTTTGGCTGACAACTCAGGTCAA
AGTTTGGAAAAAGTTCACGCTGATGCTGAACGTGATAACTGGATGAGCGCTCAAGAAACTCTTGAATATGGCTTCATCGA
TGAAATCATGGTTAACAACGAATTGAACTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A091BS49

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus thermophilus LMG 18311	95.897	99.49	0.954
clpP	Streptococcus thermophilus LMD-9	95.897	99.49	0.954
clpP	Streptococcus pneumoniae Rx1	93.367	100	0.934
clpP	Streptococcus pneumoniae D39	93.367	100	0.934
clpP	Streptococcus pneumoniae R6	93.367	100	0.934
clpP	Streptococcus pneumoniae TIGR4	93.367	100	0.934
clpP	Streptococcus pyogenes JRS4	89.286	100	0.893
clpP	Streptococcus pyogenes MGAS315	89.286	100	0.893
clpP	Streptococcus mutans UA159	88.265	100	0.883
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.755	100	0.878
clpP	Lactococcus lactis subsp. cremoris KW2	87.245	100	0.872
clpP	Bacillus subtilis subsp. subtilis str. 168	58.247	98.98	0.577
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.421	96.939	0.566