Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   KPL75_RS12335 Genome accession   NZ_CP076653
Coordinates   2314352..2314933 (+) Length   193 a.a.
NCBI ID   WP_001049156.1    Uniprot ID   J8DR96
Organism   Bacillus sp. NP247     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 2309352..2319933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KPL75_RS27815 - 2309429..2309626 (-) 198 Protein_2453 hypothetical protein -
  KPL75_RS12300 (KPL75_12295) - 2310332..2310538 (+) 207 WP_000216167.1 DUF1657 domain-containing protein -
  KPL75_RS12305 (KPL75_12300) - 2310646..2311134 (+) 489 WP_219920824.1 YhcN/YlaJ family sporulation lipoprotein -
  KPL75_RS12310 (KPL75_12305) spoVAC 2311163..2311639 (+) 477 WP_002034730.1 stage V sporulation protein AC -
  KPL75_RS12315 (KPL75_12310) spoVAD 2311640..2312653 (+) 1014 WP_219920825.1 stage V sporulation protein AD -
  KPL75_RS12320 (KPL75_12315) spoVAE 2312653..2313003 (+) 351 WP_000575919.1 stage V sporulation protein AE -
  KPL75_RS12325 (KPL75_12320) - 2313015..2313221 (+) 207 WP_167316875.1 DUF1657 domain-containing protein -
  KPL75_RS12330 (KPL75_12325) - 2313242..2314111 (+) 870 WP_219920826.1 DUF421 domain-containing protein -
  KPL75_RS12335 (KPL75_12330) clpP 2314352..2314933 (+) 582 WP_001049156.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  KPL75_RS12340 (KPL75_12335) - 2315443..2315691 (-) 249 WP_002124065.1 HPr family phosphocarrier protein -
  KPL75_RS12345 (KPL75_12340) whiA 2315715..2316665 (-) 951 WP_219920827.1 DNA-binding protein WhiA -
  KPL75_RS12350 (KPL75_12345) yvcK 2316754..2317707 (-) 954 WP_219920828.1 YvcK family protein -
  KPL75_RS12355 (KPL75_12350) rapZ 2317711..2318592 (-) 882 WP_002016084.1 RNase adapter RapZ -
  KPL75_RS12360 (KPL75_12355) - 2318613..2319071 (-) 459 WP_001190080.1 8-oxo-dGTP diphosphatase -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21431.68 Da        Isoelectric Point: 5.0423

>NTDB_id=576995 KPL75_RS12335 WP_001049156.1 2314352..2314933(+) (clpP) [Bacillus sp. NP247]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLESQDPEKDIHIYINSPGGSITAGMAIYDT
MQFIKPQVSTICIGMAASMGAFLLAAGEKGKRFALPNSEVMIHQPLGGAQGQATEIEIAAKRILFLREKLNQILADRTGQ
PLEVLQRDTDRDNFMTAERALEYGLIDKIFTNR

Nucleotide


Download         Length: 582 bp        

>NTDB_id=576995 KPL75_RS12335 WP_001049156.1 2314352..2314933(+) (clpP) [Bacillus sp. NP247]
ATGAATTTAATTCCTACAGTAATTGAACAAACAAATCGTGGAGAACGCGCTTACGATATTTACTCTCGACTATTAAAAGA
CCGCATCATTATGCTTGGTAGCGCAATTGATGACAACGTAGCAAACTCAATCGTTTCCCAGCTTTTATTCTTGGAATCTC
AAGATCCAGAAAAAGATATTCACATCTATATCAACAGCCCTGGTGGTTCTATCACAGCTGGTATGGCAATTTACGATACA
ATGCAGTTTATTAAACCACAAGTATCAACAATCTGTATCGGTATGGCTGCATCTATGGGTGCATTCTTACTTGCAGCAGG
TGAAAAAGGAAAACGTTTCGCTCTTCCTAACAGTGAAGTAATGATTCACCAACCACTTGGTGGTGCACAAGGTCAAGCGA
CTGAAATCGAAATCGCTGCAAAACGCATCCTATTCTTACGTGAAAAATTAAACCAAATCCTTGCTGACCGCACAGGTCAA
CCACTTGAAGTTCTACAACGCGACACAGACCGCGACAACTTCATGACAGCAGAAAGAGCTCTAGAATACGGTTTAATCGA
TAAGATCTTTACAAATCGTTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J8DR96

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

89.583

99.482

0.891
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.553

97.409

0.658
  clpP Streptococcus thermophilus LMG 18311

60.938

99.482

0.606
  clpP Streptococcus thermophilus LMD-9

60.938

99.482

0.606
  clpP Lactococcus lactis subsp. cremoris KW2

59.375

99.482

0.591
  clpP Streptococcus pneumoniae D39

57.812

99.482

0.575
  clpP Streptococcus pneumoniae Rx1

57.812

99.482

0.575
  clpP Streptococcus pneumoniae R6

57.812

99.482

0.575
  clpP Streptococcus pneumoniae TIGR4

57.812

99.482

0.575
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

57.292

99.482

0.57
  clpP Streptococcus mutans UA159

55.959

100

0.56
  clpP Streptococcus pyogenes JRS4

56.25

99.482

0.56
  clpP Streptococcus pyogenes MGAS315

56.25

99.482

0.56