Detailed information NTG0572444

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: KM411_RS13500
• Genome accession: NZ_CP076144
• Coordinates: 2592945..2593526 (-)
• Length: 193 a.a.
• NCBI ID: WP_000991625.1
• Uniprot ID: A0A2A8KY00
• Organism: Bacillus anthracis strain 3016
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2587945..2598526

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KM411_RS13475 (KM411_13470)	-	2588253..2589077 (-)	825	WP_000557567.1	PP2C family serine/threonine-protein phosphatase	-
KM411_RS13480 (KM411_13475)	-	2589192..2589359 (-)	168	WP_000508407.1	hypothetical protein	-
KM411_RS13485 (KM411_13480)	-	2589836..2590672 (-)	837	WP_001084757.1	ABC transporter permease	-
KM411_RS13490 (KM411_13485)	-	2590665..2591870 (-)	1206	WP_000370609.1	quaternary amine ABC transporter ATP-binding protein	-
KM411_RS13495 (KM411_13490)	-	2592042..2592899 (+)	858	WP_001227634.1	glycine betaine ABC transporter substrate-binding protein	-
KM411_RS13500 (KM411_13495)	clpP	2592945..2593526 (-)	582	WP_000991625.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
KM411_RS13505 (KM411_13500)	-	2593548..2594234 (-)	687	WP_000337487.1	RNA polymerase subunit sigma-70	-
KM411_RS13510 (KM411_13505)	-	2594378..2594644 (+)	267	WP_001125370.1	2Fe-2S iron-sulfur cluster-binding protein	-
KM411_RS13515 (KM411_13510)	rpiA	2594649..2595311 (+)	663	WP_000364536.1	ribose 5-phosphate isomerase A	-
KM411_RS13520 (KM411_13515)	-	2595419..2595853 (+)	435	WP_000555717.1	GNAT family N-acetyltransferase	-
KM411_RS13525 (KM411_13520)	-	2595984..2597351 (-)	1368	WP_001065250.1	lytic polysaccharide monooxygenase	-
KM411_RS13530 (KM411_13525)	-	2597789..2598307 (-)	519	WP_000720568.1	DNA topology modulation protein	-

Sequence

Protein

• Length: 193 a.a.
• Molecular weight: 21178.42 Da
• Isoelectric Point: 5.0776

>NTDB_id=572444 KM411_RS13500 WP_000991625.1 2592945..2593526(-) (clpP) [Bacillus anthracis strain 3016]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIVIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAQGQATEIEITAKRILKLKHDINKMIAEKTGQ
PIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK

Nucleotide

• Length: 582 bp

>NTDB_id=572444 KM411_RS13500 WP_000991625.1 2592945..2593526(-) (clpP) [Bacillus anthracis strain 3016]
ATGAATGCAATTCCATATGTTGTAGAACAAACGAAATTAGGAGAACGTTCCTATGATATATACTCAAGGTTATTAAAAGA
CCGTATTGTTATTATCGGTTCAGAAATAAATGATCAAGTAGCGAGTAGTGTAGTAGCTCAATTATTATTTTTAGAAGCAG
AAGATGCAGAGAAAGATATATTTTTATACATTAATAGCCCAGGCGGATCAACGACAGCAGGTTTTGCTATATTAGATACG
ATGAATTTAATTAAACCAGACGTGCAAACGCTATGCATGGGCTTTGCAGCATCATTTGGTGCATTGTTATTATTATCAGG
TGCAAAAGGAAAACGATTTGCACTCCCAAATAGTGAAATTATGATTCATCAGCCACTTGGTGGTGCGCAAGGGCAAGCGA
CGGAAATCGAAATCACAGCAAAAAGAATTTTAAAGTTAAAACATGATATTAATAAAATGATTGCAGAAAAAACAGGGCAA
CCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACTGCAGAAGAAGCGAAGGCATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAG

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (14-192)

3D structure

• AlphaFold DB: A0A2A8KY00

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	68.063	98.964	0.674
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	66.667	97.927	0.653
clpP	Streptococcus thermophilus LMD-9	54.688	99.482	0.544
clpP	Streptococcus pneumoniae Rx1	54.688	99.482	0.544
clpP	Streptococcus thermophilus LMG 18311	54.688	99.482	0.544
clpP	Streptococcus pneumoniae D39	54.688	99.482	0.544
clpP	Streptococcus pneumoniae R6	54.688	99.482	0.544
clpP	Streptococcus pneumoniae TIGR4	54.688	99.482	0.544
clpP	Streptococcus pyogenes MGAS315	55.556	97.927	0.544
clpP	Streptococcus pyogenes JRS4	55.556	97.927	0.544
clpP	Streptococcus mutans UA159	53.439	97.927	0.523
clpP	Lactococcus lactis subsp. cremoris KW2	51.852	97.927	0.508
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	49.735	97.927	0.487