Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   SITYG_RS05150 Genome accession   NZ_AP014880
Coordinates   1026824..1027666 (-) Length   280 a.a.
NCBI ID   WP_096362855.1    Uniprot ID   -
Organism   Streptococcus intermedius strain TYG1620     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1021824..1032666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SITYG_RS05135 (SITYG_10010) trmFO 1022664..1023998 (-) 1335 WP_096362852.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  SITYG_RS05140 (SITYG_10020) - 1024092..1024586 (-) 495 WP_096362853.1 phosphoribosylanthranilate isomerase -
  SITYG_RS05145 (SITYG_10030) topA 1024645..1026738 (-) 2094 WP_096362854.1 type I DNA topoisomerase -
  SITYG_RS05150 (SITYG_10040) dprA/cilB/dalA 1026824..1027666 (-) 843 WP_096362855.1 DNA-processing protein DprA Machinery gene
  SITYG_RS05155 (SITYG_10060) - 1027924..1028079 (-) 156 WP_158467589.1 Imm59 family immunity protein -
  SITYG_RS05160 - 1028189..1028512 (-) 324 WP_231870212.1 Imm59 family immunity protein -
  SITYG_RS05165 (SITYG_10070) - 1028514..1029203 (-) 690 WP_221761912.1 TNT domain-containing protein -
  SITYG_RS05170 (SITYG_10080) - 1029249..1029599 (-) 351 WP_096363332.1 hypothetical protein -
  SITYG_RS05180 (SITYG_10090) - 1029884..1030216 (-) 333 WP_096362859.1 Imm59 family immunity protein -
  SITYG_RS05185 (SITYG_10100) - 1030219..1030944 (-) 726 WP_231870213.1 TNT domain-containing protein -
  SITYG_RS10335 - 1031079..1031246 (-) 168 WP_158467590.1 hypothetical protein -
  SITYG_RS05190 (SITYG_10120) - 1031536..1031811 (-) 276 WP_096362861.1 hypothetical protein -
  SITYG_RS10605 (SITYG_10130) - 1031808..1032359 (-) 552 WP_231870214.1 hypothetical protein -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31189.69 Da        Isoelectric Point: 5.4063

>NTDB_id=56526 SITYG_RS05150 WP_096362855.1 1026824..1027666(-) (dprA/cilB/dalA) [Streptococcus intermedius strain TYG1620]
MNNFDIYKLKEAGLTNQQVINVLEYAEIHEKDLSAKDMAVVSECRNPALFIEKYLQLDDDLLRQEFEKFPSFSILDDVYP
WDLSEIYNPPVLLFYKGNLDLLKLPKVAVVGSRNSSRVGSQSVQKIIKELNNELVIVSGLARGIDTSAHMAALQNGGRTI
AVIGTGLDVFYPRSNKKLQSYLGEHHLVLSEYGPEAEPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGRSDGCHHLIQEGAKCITSGSDVLSEFQF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=56526 SITYG_RS05150 WP_096362855.1 1026824..1027666(-) (dprA/cilB/dalA) [Streptococcus intermedius strain TYG1620]
ATGAATAATTTTGATATTTATAAATTAAAAGAAGCCGGCTTGACAAACCAACAAGTTATCAATGTATTAGAATATGCTGA
AATACATGAAAAAGATTTGTCTGCCAAAGACATGGCAGTTGTTTCCGAATGCCGTAATCCTGCTCTTTTTATTGAAAAAT
ATTTGCAGTTAGATGATGATTTATTACGTCAAGAATTTGAGAAGTTCCCATCCTTTTCTATCTTGGACGATGTATATCCT
TGGGATTTGAGTGAAATTTATAATCCACCCGTTCTTCTTTTTTATAAAGGTAATTTGGATTTGCTAAAATTACCTAAAGT
GGCTGTTGTAGGAAGTCGGAATAGTAGCCGAGTAGGCAGTCAATCCGTTCAAAAGATTATTAAAGAGCTAAACAATGAAT
TGGTTATCGTGAGTGGTTTAGCTCGCGGAATTGATACCTCGGCTCACATGGCAGCGTTGCAAAATGGTGGTCGAACAATT
GCAGTTATCGGAACGGGCCTAGATGTGTTTTACCCAAGGTCGAATAAAAAACTCCAATCGTATTTGGGAGAACATCATCT
AGTACTTAGTGAGTATGGTCCTGAAGCAGAGCCATTAAAATTTCATTTTCCAGAGCGTAATCGGATTATAGCAGGATTGT
GTAGAGGGGTTATTGTTGCTGAAGCTAAAATGCGCTCAGGCAGCCTTATTACTTGTGAGCGAGCAATGGAAGAAGGGCGA
GATGTATTTGCTATTCCAGGGTCAATTTTAGATGGAAGAAGTGATGGCTGTCATCATTTGATTCAGGAGGGAGCAAAATG
CATCACATCAGGGTCTGACGTACTTTCTGAATTCCAGTTTTAA

Domains

Predicted by InterProScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-60)

DNA recombination-mediator protein A (DNA_processg_A)

(73-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

76.429

100

0.764
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

76.071

100

0.761
  dprA/cilB/dalA Streptococcus pneumoniae D39

76.071

100

0.761
  dprA/cilB/dalA Streptococcus pneumoniae R6

76.071

100

0.761
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

76.071

100

0.761
  dprA/cilB/dalA Streptococcus mitis SK321

75.714

100

0.757
  dprA Streptococcus mutans UA159

65.357

100

0.654
  dprA Lactococcus lactis subsp. cremoris KW2

57.143

100

0.571
  dprA Legionella pneumophila strain ERS1305867

43.154

86.071

0.371
  dprA Bacillus subtilis subsp. subtilis str. 168

48.095

75

0.361

Multiple sequence alignment