Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   LILO_RS10905 Genome accession   NC_020450
Coordinates   2253164..2254237 (-) Length   357 a.a.
NCBI ID   WP_080619357.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis IO-1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2248164..2259237
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LILO_RS10860 (lilo_2095) - 2248302..2249111 (-) 810 WP_015427158.1 metal ABC transporter permease -
  LILO_RS10865 (lilo_2096) - 2249104..2249841 (-) 738 WP_015427159.1 metal ABC transporter ATP-binding protein -
  LILO_RS10870 (lilo_2097) - 2250018..2250860 (-) 843 WP_015427160.1 metal ABC transporter substrate-binding protein -
  LILO_RS10875 (lilo_2098) - 2250857..2251294 (-) 438 WP_015427161.1 zinc-dependent MarR family transcriptional regulator -
  LILO_RS10880 (lilo_2099) comGG 2251376..2251660 (-) 285 WP_015427162.1 competence type IV pilus minor pilin ComGG Machinery gene
  LILO_RS10885 (lilo_2100) comGF 2251699..2252145 (-) 447 WP_042230641.1 competence type IV pilus minor pilin ComGF Machinery gene
  LILO_RS10890 (lilo_2101) comGE 2252108..2252404 (-) 297 WP_015427164.1 competence type IV pilus minor pilin ComGE Machinery gene
  LILO_RS10895 (lilo_2102) comGD 2252376..2252807 (-) 432 WP_015427165.1 competence type IV pilus minor pilin ComGD Machinery gene
  LILO_RS10900 (lilo_2103) comGC 2252767..2253150 (-) 384 WP_015427166.1 competence type IV pilus major pilin ComGC Machinery gene
  LILO_RS10905 (lilo_2104) comGB 2253164..2254237 (-) 1074 WP_080619357.1 competence type IV pilus assembly protein ComGB Machinery gene
  LILO_RS10910 (lilo_2105) comGA 2254131..2255069 (-) 939 WP_015427168.1 competence type IV pilus ATPase ComGA Machinery gene
  LILO_RS11780 - 2255339..2256295 (-) 957 WP_052312061.1 hypothetical protein -

Sequence

Protein


Download         Length: 357 a.a.        Molecular weight: 40358.52 Da        Isoelectric Point: 10.3132

>NTDB_id=56494 LILO_RS10905 WP_080619357.1 2253164..2254237(-) (comGB) [Lactococcus lactis subsp. lactis IO-1]
MSLGHQKIGIKKLISYLQMDISHLLKPRGKKLRLIKQAKLIQLMGNLLNSGFNLGEVINFLSLSKLVEKEFTLKMKEGLA
SGQALSELLESLSFSKNVVTQLALVEVHGNLSGTMQLVELHLKKQLKVKNKLVEVATYPILLLIFLVGIMWGLKNYLLPQ
LNSGSNFATLLINHLPLVFFSFGAFIFLLTALSVTLFKRKSAIMNFTFLVKLPLVHSFIRLYLTAYFAREWGNLIAQGVE
LRQIINLMKKQKSRIFSEVGKNLDLELNAGRSFEQAVSKLALFLPELSLMIEYGAIKDKLGLELSLYADECWEQFFTKID
RLMQLIQPLVFIFVALMIILLYAAMLLPIYSNMGSGI

Nucleotide


Download         Length: 1074 bp        

>NTDB_id=56494 LILO_RS10905 WP_080619357.1 2253164..2254237(-) (comGB) [Lactococcus lactis subsp. lactis IO-1]
TTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTACTTACAAATGGATATCTCACACCTACTGAAGCC
AAGAGGGAAAAAATTAAGACTGATTAAACAAGCCAAACTTATCCAACTGATGGGAAATCTTTTGAATAGTGGATTTAATT
TAGGAGAAGTGATAAATTTCTTATCTTTATCAAAACTTGTGGAAAAAGAATTTACATTGAAAATGAAAGAAGGTCTCGCT
TCTGGTCAAGCTTTATCAGAGCTTTTAGAAAGTCTTTCATTTTCTAAAAATGTGGTGACACAACTTGCTTTGGTAGAAGT
GCATGGTAACTTGTCAGGGACGATGCAATTGGTTGAACTTCATCTAAAAAAACAGCTTAAAGTTAAAAATAAATTAGTGG
AAGTTGCTACTTATCCAATATTGTTATTAATTTTTCTGGTTGGAATTATGTGGGGCTTAAAAAATTATTTACTACCACAA
CTCAATAGTGGCAGTAACTTTGCTACTCTATTGATTAATCATTTACCCTTAGTATTTTTTTCGTTTGGAGCTTTTATATT
TTTACTGACAGCTTTGTCAGTAACTCTTTTTAAACGAAAATCAGCAATAATGAATTTTACATTTCTTGTTAAATTACCTC
TGGTTCATTCTTTTATCCGTTTATATTTAACAGCTTACTTTGCAAGAGAATGGGGAAATCTAATTGCTCAAGGTGTCGAA
TTACGTCAAATTATTAACTTGATGAAAAAACAAAAAAGTCGAATTTTTTCAGAAGTTGGCAAGAATCTTGATTTAGAATT
GAATGCTGGTCGGTCTTTTGAACAAGCTGTCAGTAAACTTGCGCTTTTTTTACCCGAGCTCTCATTAATGATTGAATATG
GAGCTATTAAAGATAAATTAGGCTTAGAGCTTTCGCTTTATGCGGATGAATGTTGGGAACAATTTTTTACAAAGATAGAT
CGTTTAATGCAATTAATCCAACCTCTTGTTTTTATTTTTGTAGCATTGATGATTATTTTGCTATATGCAGCCATGTTACT
CCCCATCTATTCAAATATGGGTTCGGGAATATAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-348)

Type II secretion system (T2SS), protein F (T2SSF)

(41-159)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Lactococcus lactis subsp. cremoris KW2

83.284

95.518

0.796
  comYB Streptococcus gordonii str. Challis substr. CH1

53.666

95.518

0.513
  comYB Streptococcus mutans UA140

53.079

95.518

0.507
  comYB Streptococcus mutans UA159

52.786

95.518

0.504
  comGB/cglB Streptococcus pneumoniae TIGR4

51.343

93.838

0.482
  comGB/cglB Streptococcus pneumoniae D39

51.343

93.838

0.482
  comGB/cglB Streptococcus pneumoniae R6

51.343

93.838

0.482
  comGB/cglB Streptococcus pneumoniae Rx1

51.343

93.838

0.482
  comGB/cglB Streptococcus mitis SK321

51.045

93.838

0.479
  comGB/cglB Streptococcus mitis NCTC 12261

50.149

93.838

0.471

Multiple sequence alignment