Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   KCL43_RS07985 Genome accession   NZ_CP073275
Coordinates   1681649..1681834 (-) Length   61 a.a.
NCBI ID   WP_212573310.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain IN-6992     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1681649..1722414 1681649..1681834 within 0


Gene organization within MGE regions


Location: 1681649..1722414
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KCL43_RS07985 (KCL43_07985) prx 1681649..1681834 (-) 186 WP_212573310.1 Paratox Regulator
  KCL43_RS07990 (KCL43_07990) - 1682132..1682485 (+) 354 WP_212573311.1 hypothetical protein -
  KCL43_RS07995 (KCL43_07995) - 1682505..1682888 (+) 384 WP_212573312.1 hypothetical protein -
  KCL43_RS08000 (KCL43_08000) - 1682872..1684131 (+) 1260 WP_212573313.1 helicase-related protein -
  KCL43_RS08005 (KCL43_08005) - 1684115..1685410 (+) 1296 WP_212573314.1 DUF3440 domain-containing protein -
  KCL43_RS08010 (KCL43_08010) - 1685394..1685906 (+) 513 WP_212573315.1 IbrB-like domain-containing protein -
  KCL43_RS08015 (KCL43_08015) - 1685950..1686153 (+) 204 WP_212573316.1 hypothetical protein -
  KCL43_RS08020 (KCL43_08020) - 1686617..1686970 (+) 354 WP_212573317.1 hypothetical protein -
  KCL43_RS08025 (KCL43_08025) - 1686970..1687767 (+) 798 WP_212573318.1 recombinase family protein -
  KCL43_RS08030 (KCL43_08030) acrIIA3 1687928..1688281 (+) 354 WP_212573319.1 anti-CRISPR protein AcrIIA3 -
  KCL43_RS08035 (KCL43_08035) - 1688298..1688954 (+) 657 WP_212573320.1 hypothetical protein -
  KCL43_RS08040 (KCL43_08040) - 1689032..1690246 (-) 1215 WP_212573321.1 glucosaminidase domain-containing protein -
  KCL43_RS08045 (KCL43_08045) - 1690357..1690542 (-) 186 WP_212573322.1 hypothetical protein -
  KCL43_RS08050 (KCL43_08050) - 1690546..1690836 (-) 291 WP_212573323.1 hypothetical protein -
  KCL43_RS08055 (KCL43_08055) - 1690849..1691460 (-) 612 WP_212573324.1 hypothetical protein -
  KCL43_RS08060 (KCL43_08060) - 1691463..1691894 (-) 432 WP_212573325.1 DUF1617 family protein -
  KCL43_RS08065 (KCL43_08065) - 1691903..1693804 (-) 1902 WP_212573326.1 gp58-like family protein -
  KCL43_RS08070 (KCL43_08070) - 1693814..1694428 (-) 615 WP_212573327.1 hypothetical protein -
  KCL43_RS08075 (KCL43_08075) - 1694430..1695104 (-) 675 WP_212573328.1 collagen-like protein -
  KCL43_RS08080 (KCL43_08080) - 1695104..1697161 (-) 2058 WP_212573329.1 phage tail spike protein -
  KCL43_RS08085 (KCL43_08085) - 1697158..1697928 (-) 771 WP_212573330.1 distal tail protein Dit -
  KCL43_RS08090 (KCL43_08090) - 1697941..1702041 (-) 4101 WP_212573331.1 phage tail tape measure protein -
  KCL43_RS08095 (KCL43_08095) gpG 1702267..1702569 (-) 303 WP_212573332.1 phage tail assembly chaperone G -
  KCL43_RS08100 (KCL43_08100) - 1702662..1703237 (-) 576 WP_212573333.1 major tail protein -
  KCL43_RS08105 (KCL43_08105) - 1703250..1703630 (-) 381 WP_212573334.1 hypothetical protein -
  KCL43_RS08110 (KCL43_08110) - 1703623..1704021 (-) 399 WP_212573335.1 HK97 gp10 family phage protein -
  KCL43_RS08115 (KCL43_08115) - 1704023..1704385 (-) 363 WP_212573336.1 phage head-tail adapter protein -
  KCL43_RS08120 (KCL43_08120) - 1704378..1704686 (-) 309 WP_212573337.1 hypothetical protein -
  KCL43_RS08125 (KCL43_08125) - 1704686..1704859 (-) 174 WP_212573338.1 hypothetical protein -
  KCL43_RS08130 (KCL43_08130) - 1704870..1706003 (-) 1134 WP_212573339.1 phage major capsid protein -
  KCL43_RS08135 (KCL43_08135) - 1706020..1706826 (-) 807 WP_212573340.1 head maturation protease, ClpP-related -
  KCL43_RS08140 (KCL43_08140) - 1706807..1707994 (-) 1188 WP_212573341.1 phage portal protein -
  KCL43_RS08145 (KCL43_08145) - 1708147..1708359 (-) 213 WP_228294450.1 hypothetical protein -
  KCL43_RS08150 (KCL43_08150) - 1708362..1710092 (-) 1731 WP_212573342.1 terminase large subunit domain-containing protein -
  KCL43_RS08155 (KCL43_08155) - 1710105..1710422 (-) 318 WP_015984806.1 P27 family phage terminase small subunit -
  KCL43_RS08160 (KCL43_08160) - 1710565..1710870 (-) 306 WP_212573343.1 HNH endonuclease -
  KCL43_RS08165 (KCL43_08165) - 1710863..1711249 (-) 387 WP_212573344.1 hypothetical protein -
  KCL43_RS08170 (KCL43_08170) - 1711521..1712096 (-) 576 WP_212573345.1 site-specific integrase -
  KCL43_RS08175 (KCL43_08175) - 1712199..1712600 (-) 402 WP_212573346.1 transcriptional regulator -
  KCL43_RS08180 (KCL43_08180) - 1712603..1712818 (-) 216 WP_212573347.1 crAss001_48 related protein -
  KCL43_RS08185 (KCL43_08185) - 1712835..1713503 (-) 669 WP_212573348.1 DNA methyltransferase -
  KCL43_RS08190 (KCL43_08190) - 1713524..1714111 (-) 588 WP_212573349.1 class I SAM-dependent methyltransferase -
  KCL43_RS08195 (KCL43_08195) - 1714115..1714342 (-) 228 WP_212573350.1 hypothetical protein -
  KCL43_RS08200 (KCL43_08200) - 1714335..1714535 (-) 201 WP_212573351.1 hypothetical protein -
  KCL43_RS08205 (KCL43_08205) - 1714532..1714831 (-) 300 WP_111678836.1 VVA0879 family protein -
  KCL43_RS08210 (KCL43_08210) - 1714873..1715262 (-) 390 WP_111678017.1 YopX family protein -
  KCL43_RS08215 (KCL43_08215) - 1715326..1715538 (-) 213 WP_212573352.1 hypothetical protein -
  KCL43_RS08220 (KCL43_08220) - 1715547..1715687 (-) 141 WP_142240698.1 hypothetical protein -
  KCL43_RS08225 (KCL43_08225) - 1715684..1715917 (-) 234 WP_212573353.1 hypothetical protein -
  KCL43_RS08230 (KCL43_08230) - 1715898..1716281 (-) 384 WP_154803901.1 DnaD domain-containing protein -
  KCL43_RS08235 (KCL43_08235) - 1716443..1716688 (-) 246 WP_012678836.1 helix-turn-helix domain-containing protein -
  KCL43_RS08240 (KCL43_08240) - 1716892..1717095 (-) 204 WP_154388494.1 hypothetical protein -
  KCL43_RS10550 - 1717049..1717204 (-) 156 WP_410177027.1 BOW99_gp33 family protein -
  KCL43_RS08245 (KCL43_08245) - 1717354..1718070 (-) 717 WP_212573354.1 polymer-forming cytoskeletal protein -
  KCL43_RS08250 (KCL43_08250) - 1718215..1718430 (-) 216 WP_212573355.1 helix-turn-helix transcriptional regulator -
  KCL43_RS08255 (KCL43_08255) - 1718618..1719361 (+) 744 WP_212573356.1 XRE family transcriptional regulator -
  KCL43_RS08260 (KCL43_08260) - 1719421..1719891 (+) 471 WP_043052995.1 DUF6978 family protein -
  KCL43_RS08265 (KCL43_08265) - 1719917..1720693 (+) 777 WP_043052994.1 DUF1828 domain-containing protein -
  KCL43_RS08270 (KCL43_08270) - 1720981..1722414 (+) 1434 WP_212573357.1 recombinase family protein -

Sequence


Protein


Download         Length: 61 a.a.        Molecular weight: 6997.00 Da        Isoelectric Point: 3.8258

>NTDB_id=558791 KCL43_RS07985 WP_212573310.1 1681649..1681834(-) (prx) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
MLTYDEFKQAIDHGYITGDVVMIVRKNGQIFDYVLPSEEVQPWEVVTVEAVADILNELQII

Nucleotide


Download         Length: 186 bp        

>NTDB_id=558791 KCL43_RS07985 WP_212573310.1 1681649..1681834(-) (prx) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
ATGCTAACATACGATGAATTTAAGCAGGCTATTGATCATGGATATATCACAGGAGATGTGGTCATGATCGTGCGTAAAAA
CGGACAGATATTTGATTATGTGTTGCCAAGTGAGGAAGTGCAGCCTTGGGAAGTGGTGACAGTCGAGGCAGTTGCTGATA
TTTTAAACGAATTACAAATTATTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

75.862

95.082

0.721

  prx Streptococcus pyogenes MGAS315

71.186

96.721

0.689

  prx Streptococcus pyogenes MGAS8232

71.186

96.721

0.689

  prx Streptococcus pyogenes MGAS315

68.966

95.082

0.656

  prx Streptococcus pyogenes MGAS315

85.366

67.213

0.574

  prx Streptococcus pyogenes MGAS315

83.333

68.852

0.574

  prx Streptococcus pyogenes MGAS315

73.171

67.213

0.492