Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   INT76_RS10555 Genome accession   NZ_CP073084
Coordinates   2102315..2103025 (+) Length   236 a.a.
NCBI ID   WP_212570633.1    Uniprot ID   -
Organism   Streptococcus oriscaviae strain HKU75     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2097315..2108025
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INT76_RS10530 (INT76_10530) - 2098227..2099072 (+) 846 WP_212570618.1 helix-turn-helix domain-containing protein -
  INT76_RS10535 (INT76_10535) - 2099140..2099799 (-) 660 WP_212570625.1 amino acid ABC transporter permease -
  INT76_RS10540 (INT76_10540) - 2099812..2100510 (-) 699 WP_212570627.1 amino acid ABC transporter permease -
  INT76_RS10545 (INT76_10545) - 2100523..2101362 (-) 840 WP_212570629.1 transporter substrate-binding domain-containing protein -
  INT76_RS10550 (INT76_10550) - 2101372..2102133 (-) 762 WP_212570631.1 amino acid ABC transporter ATP-binding protein -
  INT76_RS10555 (INT76_10555) micA 2102315..2103025 (+) 711 WP_212570633.1 response regulator YycF Regulator
  INT76_RS10560 (INT76_10560) micB 2103018..2104367 (+) 1350 WP_212570635.1 cell wall metabolism sensor histidine kinase VicK Regulator
  INT76_RS10565 (INT76_10565) vicX 2104374..2105177 (+) 804 WP_212570637.1 MBL fold metallo-hydrolase Regulator
  INT76_RS10570 (INT76_10570) pbp2b 2105304..2107385 (+) 2082 WP_212570639.1 penicillin-binding protein PBP2B -
  INT76_RS10575 (INT76_10575) recR 2107394..2107990 (+) 597 WP_212570650.1 recombination mediator RecR -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27044.10 Da        Isoelectric Point: 4.9084

>NTDB_id=557870 INT76_RS10555 WP_212570633.1 2102315..2103025(+) (micA) [Streptococcus oriscaviae strain HKU75]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPEIDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELTETQMEVESLSKGTPELVIGDLVIVPDAFVAKKHGKELE
LTHREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYVKGND

Nucleotide


Download         Length: 711 bp        

>NTDB_id=557870 INT76_RS10555 WP_212570633.1 2102315..2103025(+) (micA) [Streptococcus oriscaviae strain HKU75]
ATGAAGAAAATTTTAATTGTAGACGACGAAAAACCAATTTCAGATATTATCAAGTTCAATATGACTCGGGAAGGCTATGA
GGTTGTCACTGCCTTTGACGGACGGGAAGCCTTGGAAGTATTTGAGGCCGAATTCCCTGATATTGTCATTTTGGATCTGA
TGCTGCCGGAGATAGACGGCCTAGAGGTGGCTCGGACTATCCGTAAGACCAGCAATGTGCCTATTTTGATGCTGTCGGCT
AAAGACAGCGAGTTCGACAAGGTTATCGGACTTGAAATCGGAGCGGATGACTATGTGACCAAGCCGTTTTCCAACCGTGA
ATTGCAGGCGCGTGTCAAGGCGCTTCTACGCCGGAGTGAGTTGACCGAAACCCAGATGGAGGTCGAATCGCTCTCCAAGG
GAACTCCTGAATTGGTTATTGGCGACCTGGTGATTGTGCCGGACGCTTTTGTGGCTAAAAAGCATGGCAAGGAGTTGGAG
TTGACCCATCGTGAATTTGAGTTGCTTCATCACCTAGCCAAGCACTTGGGCCAGGTCATGACCCGGGAACACCTCTTGGA
AACAGTTTGGGGCTATGACTACTTTGGTGATGTCCGTACGGTTGATGTAACGGTTCGTCGCCTCCGCGAAAAAATCGAAG
ATACACCGAGTCGTCCAGAATACATTCTGACCCGTCGGGGTGTCGGATATTATGTAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

84.681

99.576

0.843
  vicR Streptococcus mutans UA159

80.508

100

0.805
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.534

98.305

0.428
  covR Streptococcus salivarius strain HSISS4

42.553

99.576

0.424
  scnR Streptococcus mutans UA159

36.82

100

0.373