Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   INT76_RS10560 Genome accession   NZ_CP073084
Coordinates   2103018..2104367 (+) Length   449 a.a.
NCBI ID   WP_212570635.1    Uniprot ID   -
Organism   Streptococcus oriscaviae strain HKU75     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2098018..2109367
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INT76_RS10530 (INT76_10530) - 2098227..2099072 (+) 846 WP_212570618.1 helix-turn-helix domain-containing protein -
  INT76_RS10535 (INT76_10535) - 2099140..2099799 (-) 660 WP_212570625.1 amino acid ABC transporter permease -
  INT76_RS10540 (INT76_10540) - 2099812..2100510 (-) 699 WP_212570627.1 amino acid ABC transporter permease -
  INT76_RS10545 (INT76_10545) - 2100523..2101362 (-) 840 WP_212570629.1 transporter substrate-binding domain-containing protein -
  INT76_RS10550 (INT76_10550) - 2101372..2102133 (-) 762 WP_212570631.1 amino acid ABC transporter ATP-binding protein -
  INT76_RS10555 (INT76_10555) micA 2102315..2103025 (+) 711 WP_212570633.1 response regulator YycF Regulator
  INT76_RS10560 (INT76_10560) micB 2103018..2104367 (+) 1350 WP_212570635.1 cell wall metabolism sensor histidine kinase VicK Regulator
  INT76_RS10565 (INT76_10565) vicX 2104374..2105177 (+) 804 WP_212570637.1 MBL fold metallo-hydrolase Regulator
  INT76_RS10570 (INT76_10570) pbp2b 2105304..2107385 (+) 2082 WP_212570639.1 penicillin-binding protein PBP2B -
  INT76_RS10575 (INT76_10575) recR 2107394..2107990 (+) 597 WP_212570650.1 recombination mediator RecR -
  INT76_RS10580 (INT76_10580) - 2108080..2109126 (+) 1047 WP_212570652.1 D-alanine--D-alanine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 50892.06 Da        Isoelectric Point: 4.5537

>NTDB_id=557871 INT76_RS10560 WP_212570635.1 2103018..2104367(+) (micB) [Streptococcus oriscaviae strain HKU75]
MINQLRYLVTTTEFWFVVILIGFVIALAILLIENYRDNKQIKILNQKVKGLIEGNYSDVLDMRGSPEITDMTNSLNDLSE
VIRLTHDSLEQEKTRLSSILSYMSDGVVATDRMGRIIMINDMAQKQLGISPKDTEQADLLSILDIGDRYSFRDLLAQTPE
VVLDHVNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALQ
EAVAPSFVKVSLDETNRMMRMISDLLSLSRIDNQVGSVDVELINFTAFVTFILNRFDQMKNKDDDKGYTIIRDYQITPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGQITFSMKTTETQLIVSISDQGLGIPKADLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHKGFIWAKSEYGHGSTFTIVLPYSKDMTMDEWDDATEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=557871 INT76_RS10560 WP_212570635.1 2103018..2104367(+) (micB) [Streptococcus oriscaviae strain HKU75]
ATGATTAATCAACTACGTTATTTAGTAACTACAACGGAATTTTGGTTTGTTGTTATCCTGATCGGCTTTGTGATTGCATT
GGCAATTTTGCTGATTGAAAACTATCGGGATAATAAGCAAATCAAGATTCTTAATCAAAAGGTAAAGGGACTGATTGAAG
GAAATTATTCGGATGTCCTAGACATGCGGGGGAGTCCTGAGATTACCGATATGACCAACTCGCTCAATGATTTGTCAGAA
GTGATTCGCCTGACCCATGACAGTTTGGAGCAGGAGAAGACCCGCTTGAGCTCCATCTTGTCTTATATGAGCGATGGAGT
GGTTGCCACGGATCGGATGGGCCGTATCATTATGATTAACGATATGGCACAAAAGCAGTTGGGGATATCTCCCAAAGACA
CTGAGCAAGCAGACCTTTTGTCCATCTTGGATATTGGTGATCGCTATAGTTTTCGGGATTTGCTGGCCCAAACACCAGAG
GTTGTCTTAGACCATGTGAATGAAAACGAGGAATTTTTGACTCTGCGCGCCAATTTCGCCACGATCCGAAGTGAGAGCGG
TCTGATTTCGGGGCTTGTAGTGGTGCTTCATGACATGACCGAACAGGCCAAAGAAGAGCGCGAACGCCGACTTTTCGTAT
CCAATGTCAGCCATGAGTTGCGAACCCCTCTGACCTCGGTCAAATCCTATCTGGAGGCTTTAGACGAAGGTGCCTTGCAG
GAAGCTGTCGCTCCTAGTTTTGTCAAGGTTTCCTTGGATGAAACAAACCGCATGATGCGGATGATTTCAGATCTGTTGAG
TCTTTCGCGCATCGATAACCAAGTTGGCTCAGTTGATGTCGAGCTAATCAACTTCACCGCGTTTGTGACCTTCATCCTCA
ACCGGTTTGACCAGATGAAAAACAAGGACGATGATAAGGGCTATACCATCATTCGAGATTACCAGATTACACCGATTTGG
GTTGAGATTGATACAGACAAGATGACGCAGGTCTTGGACAATATTTTAAACAACGCTATCAAGTATTCACCAGATGGTGG
TCAGATTACCTTCAGTATGAAGACGACCGAAACCCAGTTAATCGTGTCCATTTCCGATCAGGGTCTGGGTATTCCAAAGG
CCGATTTGCCTAAGATTTTTGACCGTTTTTACCGTGTGGACAAGGCACGTTCACGGGCACAGGGTGGTTCAGGTCTAGGC
TTGGCCATTGCTAAGGAAATCATCAAACAGCACAAGGGCTTTATCTGGGCTAAAAGTGAATACGGTCATGGCTCTACCTT
TACAATCGTCCTGCCATATTCTAAGGATATGACAATGGATGAATGGGATGATGCAACAGAGGAAGAATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-199)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

69.954

97.105

0.679
  vicK Streptococcus mutans UA159

68.983

89.755

0.619