Detailed information NTG0553027

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: J7U26_RS01480
• Genome accession: NZ_CP072437
• Coordinates: 269206..270105 (+)
• Length: 299 a.a.
• NCBI ID: WP_014607953.1
• Uniprot ID: A0AAN1ZWJ0
• Organism: Streptococcus thermophilus strain S24734
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 264206..275105

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U26_RS01460 (J7U26_01450)	trkA	265342..266691 (-)	1350	WP_014607951.1	Trk system potassium transporter TrkA	-
J7U26_RS01465 (J7U26_01455)	-	266980..267489 (+)	510	WP_014607952.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
J7U26_RS01470 (J7U26_01460)	-	267801..268358 (+)	558	WP_116920097.1	ECF transporter S component	-
J7U26_RS01475 (J7U26_01465)	-	268361..269011 (+)	651	WP_011225447.1	phosphatase PAP2 family protein	-
J7U26_RS01480 (J7U26_01470)	comR	269206..270105 (+)	900	WP_014607953.1	helix-turn-helix domain-containing protein	Regulator
J7U26_RS01485	-	270343..270774 (+)	432	Protein_239	cysteine peptidase family C39 domain-containing protein	-
J7U26_RS01490	-	270804..271520 (+)	717	Protein_240	ABC transporter transmembrane domain-containing protein	-
J7U26_RS01495	comA	271542..271751 (+)	210	WP_002946147.1	hypothetical protein	Regulator
J7U26_RS01500 (J7U26_01495)	-	271806..272374 (+)	569	Protein_242	ATP-binding cassette domain-containing protein	-
J7U26_RS01505 (J7U26_01500)	-	272482..272799 (+)	318	WP_011225454.1	DUF805 domain-containing protein	-
J7U26_RS01510	-	272762..273046 (-)	285	WP_014727318.1	hypothetical protein	-
J7U26_RS01515	-	273286..274182 (-)	897	WP_224102957.1	urease cluster protein	-
J7U26_RS01520 (J7U26_01510)	-	274587..275102 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.70 Da
• Isoelectric Point: 5.0061

>NTDB_id=553027 J7U26_RS01480 WP_014607953.1 269206..270105(+) (comR) [Streptococcus thermophilus strain S24734]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=553027 J7U26_RS01480 WP_014607953.1 269206..270105(+) (comR) [Streptococcus thermophilus strain S24734]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418