Detailed information NTG0552927

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: J7U23_RS05680
• Genome accession: NZ_CP072435
• Coordinates: 1088415..1089122 (-)
• Length: 235 a.a.
• NCBI ID: WP_372589830.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24736
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1083415..1094122

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U23_RS05655 (J7U23_05615)	yidA	1083766..1084575 (+)	810	WP_011226081.1	sugar-phosphatase	-
J7U23_RS05660 (J7U23_05620)	-	1084577..1085791 (+)	1215	WP_011227270.1	aminoacyltransferase	-
J7U23_RS05665 (J7U23_05625)	-	1085843..1086204 (-)	362	Protein_1061	YbaN family protein	-
J7U23_RS05670 (J7U23_05630)	vicX	1086264..1087076 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
J7U23_RS05675 (J7U23_05635)	vicK	1087082..1088422 (-)	1341	WP_011226083.1	cell wall metabolism sensor histidine kinase VicK	Regulator
J7U23_RS05680 (J7U23_05640)	vicR	1088415..1089122 (-)	708	WP_372589830.1	response regulator YycF	Regulator
J7U23_RS05685 (J7U23_05645)	-	1089649..1090416 (+)	768	WP_011227275.1	amino acid ABC transporter ATP-binding protein	-
J7U23_RS05690 (J7U23_05650)	-	1090428..1091261 (+)	834	WP_179970874.1	transporter substrate-binding domain-containing protein	-
J7U23_RS05695 (J7U23_05655)	-	1091279..1091977 (+)	699	WP_065973256.1	amino acid ABC transporter permease	-
J7U23_RS05700 (J7U23_05660)	-	1091989..1092639 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
J7U23_RS05705 (J7U23_05665)	endA	1092710..1093591 (-)	882	WP_260214866.1	DNA/RNA non-specific endonuclease	Machinery gene
J7U23_RS05710 (J7U23_05670)	-	1093653..1093841 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27135.08 Da
• Isoelectric Point: 5.0130

>NTDB_id=552927 J7U23_RS05680 WP_372589830.1 1088415..1089122(-) (vicR) [Streptococcus thermophilus strain S24736]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESYNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=552927 J7U23_RS05680 WP_372589830.1 1088415..1089122(-) (vicR) [Streptococcus thermophilus strain S24736]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGAAGAGAGCTATAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGAGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Streptococcus salivarius strain HSISS4	45.923	99.149	0.455
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
scnR	Streptococcus mutans UA159	38.559	100	0.387