Detailed information NTG0552928

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: J7U23_RS05705
• Genome accession: NZ_CP072435
• Coordinates: 1092710..1093591 (-)
• Length: 293 a.a.
• NCBI ID: WP_260214866.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24736
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1087710..1098591

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U23_RS05680 (J7U23_05640)	vicR	1088415..1089122 (-)	708	WP_372589830.1	response regulator YycF	Regulator
J7U23_RS05685 (J7U23_05645)	-	1089649..1090416 (+)	768	WP_011227275.1	amino acid ABC transporter ATP-binding protein	-
J7U23_RS05690 (J7U23_05650)	-	1090428..1091261 (+)	834	WP_179970874.1	transporter substrate-binding domain-containing protein	-
J7U23_RS05695 (J7U23_05655)	-	1091279..1091977 (+)	699	WP_065973256.1	amino acid ABC transporter permease	-
J7U23_RS05700 (J7U23_05660)	-	1091989..1092639 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
J7U23_RS05705 (J7U23_05665)	endA	1092710..1093591 (-)	882	WP_260214866.1	DNA/RNA non-specific endonuclease	Machinery gene
J7U23_RS05710 (J7U23_05670)	-	1093653..1093841 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
J7U23_RS05715 (J7U23_05675)	murA	1093843..1095114 (-)	1272	WP_164178134.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
J7U23_RS05720 (J7U23_05680)	-	1095184..1095420 (-)	237	WP_002946959.1	DUF1146 family protein	-
J7U23_RS05725 (J7U23_05685)	galE	1095608..1096621 (-)	1014	WP_372589831.1	UDP-glucose 4-epimerase GalE	-
J7U23_RS05730 (J7U23_05690)	-	1096636..1097091 (-)	456	WP_372589832.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31746.52 Da
• Isoelectric Point: 10.2316

>NTDB_id=552928 J7U23_RS05705 WP_260214866.1 1092710..1093591(-) (endA) [Streptococcus thermophilus strain S24736]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRKVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQSYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=552928 J7U23_RS05705 WP_260214866.1 1092710..1093591(-) (endA) [Streptococcus thermophilus strain S24736]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGAAAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAGCTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterProScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.385	81.57	0.59
endA	Streptococcus pneumoniae D39	72.385	81.57	0.59
endA	Streptococcus pneumoniae R6	72.385	81.57	0.59
endA	Streptococcus pneumoniae TIGR4	72.385	81.57	0.59