Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   LXA46_RS10090 Genome accession   NZ_CP089948
Coordinates   1990948..1991352 (-) Length   134 a.a.
NCBI ID   WP_224781841.1    Uniprot ID   -
Organism   Streptococcus pneumoniae TIGR4     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1985948..1996352
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXA46_RS10060 (LXA46_10045) - 1986257..1987132 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  LXA46_RS10065 (LXA46_10050) pstC 1987250..1988113 (+) 864 WP_000165887.1 phosphate ABC transporter permease subunit PstC -
  LXA46_RS10070 (LXA46_10055) pstA 1988106..1988921 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  LXA46_RS10075 (LXA46_10060) pstB 1988923..1989675 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  LXA46_RS10080 (LXA46_10065) phoU 1989690..1990340 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  LXA46_RS10085 (LXA46_10070) - 1990402..1990833 (+) 432 Protein_1977 transposase -
  LXA46_RS10090 (LXA46_10075) comR 1990948..1991352 (-) 405 WP_224781841.1 helix-turn-helix transcriptional regulator Regulator
  LXA46_RS10095 (LXA46_10080) - 1991600..1992616 (+) 1017 WP_000415103.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  LXA46_RS10100 (LXA46_10085) galU 1992638..1993537 (+) 900 WP_000202234.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  LXA46_RS10105 (LXA46_10090) - 1993955..1994896 (+) 942 WP_000428163.1 hypothetical protein -
  LXA46_RS10110 (LXA46_10095) - 1994998..1995183 (-) 186 WP_000693096.1 hypothetical protein -
  LXA46_RS10115 (LXA46_10100) - 1995197..1995874 (-) 678 WP_000658497.1 rhomboid family intramembrane serine protease -

Sequence

Protein


Download         Length: 134 a.a.        Molecular weight: 16159.57 Da        Isoelectric Point: 4.5898

>NTDB_id=552736 LXA46_RS10090 WP_224781841.1 1990948..1991352(-) (comR) [Streptococcus pneumoniae TIGR4]
MAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETI
AQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 405 bp        

>NTDB_id=552736 LXA46_RS10090 WP_224781841.1 1990948..1991352(-) (comR) [Streptococcus pneumoniae TIGR4]
TTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTAGAATTGAAAA
TGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTGAACGTTTGGGGGTTGAAGATTACAAGTTGATGCCAA
GTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGATGAAACTATC
GCCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAAGATTTATCAT
CCCAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCT
GGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(60-107)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

54.63

80.597

0.44
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

55.66

79.104

0.44
  comR Streptococcus pyogenes MGAS315

52.778

80.597

0.425
  comR Streptococcus mutans UA159

50.926

80.597

0.41
  comR Streptococcus suis P1/7

48.113

79.104

0.381
  comR Streptococcus suis 05ZYH33

48.113

79.104

0.381
  comR Streptococcus suis D9

47.17

79.104

0.373
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

48.039

76.119

0.366