Detailed information NTG0552679

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: J7T77_RS01480
• Genome accession: NZ_CP072430
• Coordinates: 268637..269536 (+)
• Length: 299 a.a.
• NCBI ID: WP_014607953.1
• Uniprot ID: A0AAN1ZWJ0
• Organism: Streptococcus thermophilus strain S24746
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 263637..274536

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T77_RS01460 (J7T77_01445)	trkA	264774..266123 (-)	1350	WP_011225444.1	Trk system potassium transporter TrkA	-
J7T77_RS01465 (J7T77_01450)	-	266382..266921 (+)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
J7T77_RS01470 (J7T77_01455)	-	267232..267789 (+)	558	WP_111679227.1	ECF transporter S component	-
J7T77_RS01475 (J7T77_01460)	-	267792..268442 (+)	651	WP_193838187.1	phosphatase PAP2 family protein	-
J7T77_RS01480 (J7T77_01465)	comR	268637..269536 (+)	900	WP_014607953.1	helix-turn-helix domain-containing protein	Regulator
J7T77_RS01485	-	269774..270205 (+)	432	Protein_239	cysteine peptidase family C39 domain-containing protein	-
J7T77_RS01490	-	270235..270951 (+)	717	Protein_240	ABC transporter transmembrane domain-containing protein	-
J7T77_RS01495	comA	270973..271806 (+)	834	WP_269149495.1	ATP-binding cassette domain-containing protein	Regulator
J7T77_RS01500 (J7T77_01475)	-	271914..272231 (+)	318	WP_179970762.1	DUF805 domain-containing protein	-
J7T77_RS01505	-	272246..272479 (-)	234	WP_372589698.1	hypothetical protein	-
J7T77_RS01510	-	272448..272795 (-)	348	WP_232085744.1	DUF4153 domain-containing protein	-
J7T77_RS01515	-	272720..273520 (-)	801	WP_232086444.1	urease cluster protein	-
J7T77_RS01520 (J7T77_01485)	-	274021..274536 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.70 Da
• Isoelectric Point: 5.0061

>NTDB_id=552679 J7T77_RS01480 WP_014607953.1 268637..269536(+) (comR) [Streptococcus thermophilus strain S24746]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=552679 J7T77_RS01480 WP_014607953.1 268637..269536(+) (comR) [Streptococcus thermophilus strain S24746]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418