Detailed information
Bioinformatically predicted
Overview
| Name | comEA/celA/cilE | Type | Machinery gene |
| Locus tag | J5M87_RS02730 | Genome accession | NZ_CP072115 |
| Coordinates | 537448..538077 (+) | Length | 209 a.a. |
| NCBI ID | WP_154608222.1 | Uniprot ID | - |
| Organism | Streptococcus zhangguiae strain zg-86 | ||
| Function | dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 538061..572506 | 537448..538077 | flank | -16 |
Gene organization within MGE regions
Location: 537448..572506
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J5M87_RS02730 (J5M87_02730) | comEA/celA/cilE | 537448..538077 (+) | 630 | WP_154608222.1 | helix-hairpin-helix domain-containing protein | Machinery gene |
| J5M87_RS02735 (J5M87_02735) | comEC/celB | 538061..540298 (+) | 2238 | WP_154608223.1 | DNA internalization-related competence protein ComEC/Rec2 | Machinery gene |
| J5M87_RS02740 (J5M87_02740) | - | 541203..542096 (+) | 894 | WP_154608224.1 | ABC transporter ATP-binding protein | - |
| J5M87_RS02745 (J5M87_02745) | - | 542080..544407 (+) | 2328 | WP_154608225.1 | hypothetical protein | - |
| J5M87_RS02750 (J5M87_02750) | - | 544714..545880 (-) | 1167 | WP_154608226.1 | site-specific integrase | - |
| J5M87_RS02755 (J5M87_02755) | - | 546062..546559 (-) | 498 | WP_230082356.1 | hypothetical protein | - |
| J5M87_RS02760 (J5M87_02760) | - | 546570..546986 (-) | 417 | WP_154608227.1 | hypothetical protein | - |
| J5M87_RS02765 (J5M87_02765) | - | 547112..547663 (-) | 552 | WP_154608228.1 | zinc ribbon domain-containing protein | - |
| J5M87_RS02770 (J5M87_02770) | - | 547870..548796 (-) | 927 | WP_230082357.1 | Abi family protein | - |
| J5M87_RS02775 (J5M87_02775) | - | 548793..549512 (-) | 720 | WP_230082358.1 | XRE family transcriptional regulator | - |
| J5M87_RS02780 (J5M87_02780) | - | 550318..550473 (+) | 156 | WP_068994103.1 | DNA-binding protein | - |
| J5M87_RS02785 (J5M87_02785) | - | 550633..550806 (+) | 174 | WP_230082359.1 | helix-turn-helix domain-containing protein | - |
| J5M87_RS02790 (J5M87_02790) | - | 550904..551110 (-) | 207 | WP_154608229.1 | hypothetical protein | - |
| J5M87_RS02795 (J5M87_02795) | - | 551254..551433 (+) | 180 | WP_154608230.1 | helix-turn-helix transcriptional regulator | - |
| J5M87_RS02800 (J5M87_02800) | - | 551508..551777 (+) | 270 | WP_154608231.1 | hypothetical protein | - |
| J5M87_RS02805 (J5M87_02805) | - | 551774..551953 (+) | 180 | WP_154608232.1 | hypothetical protein | - |
| J5M87_RS02810 (J5M87_02810) | - | 551928..552080 (+) | 153 | WP_154608233.1 | hypothetical protein | - |
| J5M87_RS02815 (J5M87_02815) | - | 552077..552424 (+) | 348 | WP_154608234.1 | hypothetical protein | - |
| J5M87_RS02820 (J5M87_02820) | - | 552421..552609 (+) | 189 | WP_154608235.1 | hypothetical protein | - |
| J5M87_RS02825 (J5M87_02825) | - | 552606..552938 (+) | 333 | WP_154608236.1 | hypothetical protein | - |
| J5M87_RS02830 (J5M87_02830) | - | 552935..553618 (+) | 684 | WP_154608237.1 | AAA family ATPase | - |
| J5M87_RS02835 (J5M87_02835) | - | 553618..555069 (+) | 1452 | WP_154608238.1 | DEAD/DEAH box helicase | - |
| J5M87_RS02840 (J5M87_02840) | - | 555073..555546 (+) | 474 | WP_154608239.1 | DUF669 domain-containing protein | - |
| J5M87_RS02845 (J5M87_02845) | - | 555563..557113 (+) | 1551 | WP_154608240.1 | phage resistance protein | - |
| J5M87_RS02850 (J5M87_02850) | - | 557371..558246 (+) | 876 | WP_160463206.1 | bifunctional DNA primase/polymerase | - |
| J5M87_RS02855 (J5M87_02855) | - | 558227..558553 (+) | 327 | WP_154608241.1 | VRR-NUC domain-containing protein | - |
| J5M87_RS02860 (J5M87_02860) | - | 558546..559130 (+) | 585 | WP_154608242.1 | DUF1642 domain-containing protein | - |
| J5M87_RS02865 (J5M87_02865) | - | 559130..559420 (+) | 291 | WP_154608243.1 | hypothetical protein | - |
| J5M87_RS02870 (J5M87_02870) | - | 559407..559739 (+) | 333 | WP_154608244.1 | helix-turn-helix transcriptional regulator | - |
| J5M87_RS02875 (J5M87_02875) | - | 559779..560213 (+) | 435 | WP_160463205.1 | ArpU family phage packaging/lysis transcriptional regulator | - |
| J5M87_RS02885 (J5M87_02885) | - | 560496..561368 (+) | 873 | WP_154608245.1 | hypothetical protein | - |
| J5M87_RS02890 (J5M87_02890) | - | 561422..561919 (+) | 498 | WP_230082360.1 | terminase small subunit | - |
| J5M87_RS02895 (J5M87_02895) | - | 561927..563237 (+) | 1311 | WP_230082361.1 | terminase | - |
| J5M87_RS02900 (J5M87_02900) | - | 563250..564806 (+) | 1557 | WP_154608247.1 | phage portal protein | - |
| J5M87_RS02905 (J5M87_02905) | - | 564941..566515 (+) | 1575 | WP_154608248.1 | phage minor capsid protein | - |
| J5M87_RS02910 (J5M87_02910) | - | 566502..566723 (+) | 222 | WP_154608249.1 | hypothetical protein | - |
| J5M87_RS09850 | - | 566779..566913 (+) | 135 | WP_258232206.1 | hypothetical protein | - |
| J5M87_RS02915 (J5M87_02915) | - | 566910..567200 (+) | 291 | WP_154608250.1 | hypothetical protein | - |
| J5M87_RS02920 (J5M87_02920) | - | 567318..567905 (+) | 588 | WP_154608251.1 | hypothetical protein | - |
| J5M87_RS02925 (J5M87_02925) | - | 567921..568820 (+) | 900 | WP_154608252.1 | capsid protein | - |
| J5M87_RS02930 (J5M87_02930) | - | 568835..569095 (+) | 261 | WP_154608253.1 | hypothetical protein | - |
| J5M87_RS02935 (J5M87_02935) | - | 569097..569465 (+) | 369 | WP_154608254.1 | hypothetical protein | - |
| J5M87_RS02940 (J5M87_02940) | - | 569665..571225 (-) | 1561 | Protein_538 | IS1182 family transposase | - |
| J5M87_RS02945 (J5M87_02945) | holA | 571475..572506 (+) | 1032 | WP_154608673.1 | DNA polymerase III subunit delta | - |
Sequence
Protein
Download Length: 209 a.a. Molecular weight: 22261.13 Da Isoelectric Point: 4.7838
>NTDB_id=550533 J5M87_RS02730 WP_154608222.1 537448..538077(+) (comEA/celA/cilE) [Streptococcus zhangguiae strain zg-86]
MVEKWIQILRDYKWQIVVPSGIIVAIATVFVMGQTAHTEEQISLTELATSSEQVVEQPSSSHSESQLVVDVKGAVRKPGI
YHLSIGSRIHDAVEAAGGLAETADSKSINLAQKLSDEGVVYVATKEEAISLIPASSANGDKGEKGSLVNLNTATEADLQT
ISGIGAKRAADIIAYRESNGPFQSVDDLKNVSGIGGKRLEMIRPYVTVD
MVEKWIQILRDYKWQIVVPSGIIVAIATVFVMGQTAHTEEQISLTELATSSEQVVEQPSSSHSESQLVVDVKGAVRKPGI
YHLSIGSRIHDAVEAAGGLAETADSKSINLAQKLSDEGVVYVATKEEAISLIPASSANGDKGEKGSLVNLNTATEADLQT
ISGIGAKRAADIIAYRESNGPFQSVDDLKNVSGIGGKRLEMIRPYVTVD
Nucleotide
Download Length: 630 bp
>NTDB_id=550533 J5M87_RS02730 WP_154608222.1 537448..538077(+) (comEA/celA/cilE) [Streptococcus zhangguiae strain zg-86]
ATGGTTGAAAAATGGATACAGATTCTACGTGACTATAAATGGCAAATTGTAGTGCCGTCTGGAATCATAGTAGCGATAGC
GACTGTTTTTGTGATGGGACAAACAGCTCATACAGAAGAGCAAATTAGTTTAACGGAGTTAGCAACTAGTAGTGAGCAAG
TTGTTGAACAGCCCTCTAGTTCCCACTCAGAATCGCAGCTTGTAGTAGATGTCAAGGGAGCGGTCAGAAAGCCGGGGATT
TACCATTTGTCGATAGGAAGTCGCATCCATGATGCTGTAGAAGCGGCAGGAGGCTTGGCAGAGACAGCCGATTCCAAGTC
TATCAATTTGGCTCAGAAGTTAAGTGATGAGGGAGTCGTTTATGTAGCGACCAAGGAGGAAGCTATTTCGCTTATTCCTG
CTTCTTCAGCAAACGGAGATAAGGGTGAAAAAGGAAGTCTCGTCAATCTGAACACTGCAACAGAAGCAGACCTGCAGACG
ATTTCAGGCATTGGTGCTAAGCGAGCTGCAGATATTATTGCCTATCGTGAGAGTAATGGTCCCTTTCAGTCGGTTGATGA
TTTGAAGAATGTTTCAGGAATAGGTGGCAAGAGATTGGAGATGATTCGTCCGTATGTCACAGTTGATTAG
ATGGTTGAAAAATGGATACAGATTCTACGTGACTATAAATGGCAAATTGTAGTGCCGTCTGGAATCATAGTAGCGATAGC
GACTGTTTTTGTGATGGGACAAACAGCTCATACAGAAGAGCAAATTAGTTTAACGGAGTTAGCAACTAGTAGTGAGCAAG
TTGTTGAACAGCCCTCTAGTTCCCACTCAGAATCGCAGCTTGTAGTAGATGTCAAGGGAGCGGTCAGAAAGCCGGGGATT
TACCATTTGTCGATAGGAAGTCGCATCCATGATGCTGTAGAAGCGGCAGGAGGCTTGGCAGAGACAGCCGATTCCAAGTC
TATCAATTTGGCTCAGAAGTTAAGTGATGAGGGAGTCGTTTATGTAGCGACCAAGGAGGAAGCTATTTCGCTTATTCCTG
CTTCTTCAGCAAACGGAGATAAGGGTGAAAAAGGAAGTCTCGTCAATCTGAACACTGCAACAGAAGCAGACCTGCAGACG
ATTTCAGGCATTGGTGCTAAGCGAGCTGCAGATATTATTGCCTATCGTGAGAGTAATGGTCCCTTTCAGTCGGTTGATGA
TTTGAAGAATGTTTCAGGAATAGGTGGCAAGAGATTGGAGATGATTCGTCCGTATGTCACAGTTGATTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comEA/celA/cilE | Streptococcus pneumoniae Rx1 |
46.396 |
100 |
0.493 |
| comEA/celA/cilE | Streptococcus pneumoniae D39 |
46.396 |
100 |
0.493 |
| comEA/celA/cilE | Streptococcus pneumoniae R6 |
46.396 |
100 |
0.493 |
| comEA/celA/cilE | Streptococcus pneumoniae TIGR4 |
45 |
100 |
0.474 |
| comEA/celA/cilE | Streptococcus mitis NCTC 12261 |
44.7 |
100 |
0.464 |
| comEA/celA/cilE | Streptococcus mitis SK321 |
43.318 |
100 |
0.45 |
| comEA | Streptococcus thermophilus LMD-9 |
56.129 |
74.163 |
0.416 |
| comEA | Bacillus subtilis subsp. subtilis str. 168 |
40.196 |
97.608 |
0.392 |