Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   J5M87_RS02590 Genome accession   NZ_CP072115
Coordinates   507782..508486 (+) Length   234 a.a.
NCBI ID   WP_154608197.1    Uniprot ID   A0A6I4REA5
Organism   Streptococcus zhangguiae strain zg-86     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 502782..513486
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5M87_RS02565 (J5M87_02565) - 503505..503873 (+) 369 WP_230082355.1 nuclear transport factor 2 family protein -
  J5M87_RS02570 (J5M87_02570) adhP 503942..504958 (-) 1017 WP_154608194.1 alcohol dehydrogenase AdhP -
  J5M87_RS02580 (J5M87_02580) - 505838..506470 (-) 633 WP_154608195.1 HXXEE domain-containing protein -
  J5M87_RS02585 (J5M87_02585) - 506571..507194 (+) 624 WP_154608196.1 TetR/AcrR family transcriptional regulator -
  J5M87_RS02590 (J5M87_02590) micA 507782..508486 (+) 705 WP_154608197.1 response regulator YycF Regulator
  J5M87_RS02595 (J5M87_02595) micB 508479..509828 (+) 1350 WP_154608198.1 cell wall metabolism sensor histidine kinase VicK Regulator
  J5M87_RS02600 (J5M87_02600) vicX 509835..510638 (+) 804 WP_154608199.1 MBL fold metallo-hydrolase Regulator
  J5M87_RS02605 (J5M87_02605) abc-f 511223..512632 (+) 1410 WP_154608200.1 ribosomal protection-like ABC-F family protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26897.94 Da        Isoelectric Point: 4.9967

>NTDB_id=550528 J5M87_RS02590 WP_154608197.1 507782..508486(+) (micA) [Streptococcus zhangguiae strain zg-86]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALALFEAEFPDIVILDLMLPEIDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELSETQLEIETTGTPELTIRDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=550528 J5M87_RS02590 WP_154608197.1 507782..508486(+) (micA) [Streptococcus zhangguiae strain zg-86]
ATGAAAAAAATCTTGATTGTAGATGATGAAAAGCCGATTTCAGACATTATCAAATTTAATATGACCCGAGAGGGGTATGA
GGTGGTGACAGCCTTTGATGGTCGAGAAGCCTTGGCCTTATTTGAAGCAGAATTTCCAGATATTGTGATTTTGGATTTGA
TGCTACCAGAAATTGATGGACTGGAAGTGGCACGCACCATTCGCAAGACCAGCAATGTGCCTATTTTGATGTTATCTGCT
AAGGATAGCGAGTTTGACAAGGTGATTGGTCTTGAAATTGGAGCGGATGACTATGTGACGAAGCCGTTTTCGAATCGGGA
ATTGCAGGCACGGGTCAAGGCCTTATTGCGCCGGAGCGAATTGTCTGAAACCCAGTTGGAGATTGAAACAACAGGCACGC
CTGAGTTGACCATTCGAGATTTGGTGATTCTTCCAGATGCTTTTGTGGCGAAAAAACATGGCAAGGAGTTGGAATTGACT
CACCGTGAATTTGAATTGCTGCACCATTTAGCTAAGCATTTGGGGCAGGTAATGACACGGGAACATTTACTTGAAACTGT
ATGGGGCTATGATTACTTTGGTGATGTACGAACAGTCGATGTAACGGTTCGTCGCTTGCGTGAGAAGATTGAAGATACAC
CGAGCCGTCCAGAATACATTTTGACACGGCGTGGCGTAGGGTATTATATAAAGGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I4REA5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.403

99.573

0.821
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.913

98.291

0.432
  covR Streptococcus salivarius strain HSISS4

43.29

98.718

0.427
  scnR Streptococcus mutans UA159

37.131

100

0.376