Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   J5M87_RS02595 Genome accession   NZ_CP072115
Coordinates   508479..509828 (+) Length   449 a.a.
NCBI ID   WP_154608198.1    Uniprot ID   A0A6I4R9I7
Organism   Streptococcus zhangguiae strain zg-86     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 503479..514828
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5M87_RS02565 (J5M87_02565) - 503505..503873 (+) 369 WP_230082355.1 nuclear transport factor 2 family protein -
  J5M87_RS02570 (J5M87_02570) adhP 503942..504958 (-) 1017 WP_154608194.1 alcohol dehydrogenase AdhP -
  J5M87_RS02580 (J5M87_02580) - 505838..506470 (-) 633 WP_154608195.1 HXXEE domain-containing protein -
  J5M87_RS02585 (J5M87_02585) - 506571..507194 (+) 624 WP_154608196.1 TetR/AcrR family transcriptional regulator -
  J5M87_RS02590 (J5M87_02590) micA 507782..508486 (+) 705 WP_154608197.1 response regulator YycF Regulator
  J5M87_RS02595 (J5M87_02595) micB 508479..509828 (+) 1350 WP_154608198.1 cell wall metabolism sensor histidine kinase VicK Regulator
  J5M87_RS02600 (J5M87_02600) vicX 509835..510638 (+) 804 WP_154608199.1 MBL fold metallo-hydrolase Regulator
  J5M87_RS02605 (J5M87_02605) abc-f 511223..512632 (+) 1410 WP_154608200.1 ribosomal protection-like ABC-F family protein -
  J5M87_RS02610 (J5M87_02610) pbp2b 512717..514792 (+) 2076 WP_208769378.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51311.54 Da        Isoelectric Point: 4.6005

>NTDB_id=550529 J5M87_RS02595 WP_154608198.1 508479..509828(+) (micB) [Streptococcus zhangguiae strain zg-86]
MINQLRYLITTPEFWFVVILIGFVIALSVLLIENHRDNQQIKELNEKVKRLIELDYSDVLDMRGSPEITDMANSLNDLSE
VIRLTHDHLEQEKTRLSSILAYMSDGVMAADRMGRVIMVNETAQKQLGLTSKTTEQRDLLDILGIREQYSFRDLLAQTPE
IVIEHDNENGEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALT
ESVAPSFVKVSLDETNRMMRMISDLLSLSRIDNQVSSADVELINFTAFVTFILNRFDQMKNKETDKEYTIIRDYQITPIW
IEIDTDKMTQVMDNILNNALKYSPDGGKITFSMKTTDTQLIVSISDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYMKDMMTDEWEEAEEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=550529 J5M87_RS02595 WP_154608198.1 508479..509828(+) (micB) [Streptococcus zhangguiae strain zg-86]
ATGATTAATCAATTACGGTATTTAATAACAACACCTGAGTTTTGGTTTGTCGTCATCTTGATTGGTTTTGTCATTGCACT
CAGTGTCTTATTGATTGAAAATCATCGCGATAATCAGCAGATTAAAGAACTCAATGAAAAAGTCAAGCGCCTAATCGAGT
TGGATTATTCAGATGTCCTTGATATGCGGGGTAGCCCTGAGATTACAGATATGGCCAATTCGCTCAATGACTTGTCTGAA
GTGATTCGCTTGACCCATGACCATTTGGAGCAGGAAAAGACGCGTCTGTCCTCCATTCTTGCCTATATGAGCGACGGAGT
GATGGCTGCAGACCGTATGGGCCGAGTCATTATGGTCAATGAGACAGCGCAAAAGCAGTTGGGACTGACATCTAAAACGA
CGGAACAACGTGATTTATTGGACATTTTAGGGATTCGTGAACAGTATAGTTTTCGGGATTTGCTAGCCCAAACGCCTGAA
ATTGTCATCGAACATGATAATGAAAATGGGGAGTTTTTGACCTTACGGGCCAATTTTGCAACGATTCGAAGCGAAAGTGG
TTTGATTTCAGGTCTGGTCGTCGTCTTGCATGATATGACCGAACAAGCTAAGGAAGAGCGGGAGCGACGGTTGTTCGTTT
CCAATGTCAGCCATGAATTGCGGACACCGCTCACCTCAGTCAAATCCTATCTGGAGGCCCTTGATGATGGAGCCTTGACG
GAATCAGTAGCACCGAGCTTTGTCAAGGTGTCACTCGATGAAACCAATCGGATGATGCGGATGATTTCAGACCTGCTCAG
CCTGTCACGGATTGACAATCAAGTCAGCTCAGCTGATGTGGAACTGATTAACTTTACGGCCTTTGTCACCTTTATTTTAA
ATCGATTTGATCAGATGAAGAATAAGGAGACAGATAAGGAATATACGATTATCCGTGATTATCAAATTACACCGATTTGG
ATTGAGATTGACACAGACAAGATGACCCAGGTCATGGATAATATTTTAAACAATGCCCTCAAATACTCACCTGATGGTGG
CAAGATTACCTTTAGCATGAAGACGACAGATACCCAATTGATTGTGTCGATTTCAGATGAAGGATTAGGAATTCCCAAGG
CTGATTTGCCCCGCATTTTTGATCGTTTTTATCGAGTGGATAAGGCTCGTTCAAGGGCGCAAGGTGGGACAGGACTTGGC
CTTGCTATTGCCAAGGAAATTGTTAAGCAGCATAAGGGCTTTATCTGGGCTAAGAGCGAGTACGGGCATGGCTCAACCTT
TACCATTGTCTTACCATATATGAAGGATATGATGACAGATGAGTGGGAGGAGGCAGAAGAGGAAGAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-199)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I4R9I7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

69.495

97.105

0.675
  vicK Streptococcus mutans UA159

68.983

89.755

0.619