NTDB

Overview

Name	comEA/celA/cilE	Type	Machinery gene
Locus tag	JN057_RS04570	Genome accession	NZ_CP071871
Coordinates	886041..886691 (+)	Length	216 a.a.
NCBI ID	WP_000387352.1	Uniprot ID	A0A4J1SCX2
Organism	Streptococcus pneumoniae strain BVJ1JL
Function	dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 881041..891691

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JN057_RS04540 (JN057_00932)	-	881537..881752 (+)	216	WP_001232078.1	YozE family protein	-
JN057_RS04545 (JN057_00933)	-	881838..882806 (+)	969	WP_000658180.1	PhoH family protein	-
JN057_RS04550 (JN057_00934)	-	882986..883486 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
JN057_RS04555 (JN057_00935)	-	883489..883815 (+)	327	Protein_909	TfoX/Sxy family protein	-
JN057_RS04560 (JN057_00937)	ald	884116..885227 (-)	1112	Protein_910	alanine dehydrogenase	-
JN057_RS04565 (JN057_00938)	-	885404..885973 (+)	570	WP_000443745.1	GNAT family N-acetyltransferase	-
JN057_RS04570 (JN057_00939)	comEA/celA/cilE	886041..886691 (+)	651	WP_000387352.1	helix-hairpin-helix domain-containing protein	Machinery gene
JN057_RS04575 (JN057_00940)	comEC/celB	886675..888915 (+)	2241	WP_000942420.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
JN057_RS04580	-	889094..889282 (+)	189	WP_001812421.1	hypothetical protein	-
JN057_RS04585 (JN057_00941)	-	889315..889902 (+)	588	WP_000939895.1	ATP-binding cassette domain-containing protein	-
JN057_RS04590 (JN057_00942)	-	889906..891090 (+)	1185	WP_000655953.1	hypothetical protein	-

Sequence

Protein

Download Length: 216 a.a. Molecular weight: 23085.30 Da Isoelectric Point: 6.0661

                                >NTDB_id=548613 JN057_RS04570 WP_000387352.1 886041..886691(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain BVJ1JL]

MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQAEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKG

AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA

SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide

Download Length: 651 bp

                                >NTDB_id=548613 JN057_RS04570 WP_000387352.1 886041..886691(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain BVJ1JL]

ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT

TTTCCTGCTAAAGCCAGCTCCACAAACATCTGTCAAAGAGACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGACT

CATCGACCGGAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT

GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC

AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG

AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC

AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATTGACCATCGTGAGGCAAATGG

CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGCCAAGACCATAGAAAAACTTAAAGACTATGTTA

CAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(151-214)

SLBB domain (SLBB)

(76-126)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A4J1SCX2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	97.685	100	0.977
comEA/celA/cilE	Streptococcus pneumoniae Rx1	95.833	100	0.958
comEA/celA/cilE	Streptococcus pneumoniae D39	95.833	100	0.958
comEA/celA/cilE	Streptococcus pneumoniae R6	95.833	100	0.958
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.37	100	0.954
comEA/celA/cilE	Streptococcus mitis SK321	92.593	100	0.926
comEA	Lactococcus lactis subsp. cremoris KW2	44.053	100	0.463
comEA	Latilactobacillus sakei subsp. sakei 23K	34.335	100	0.37

Detailed information NTG0548613