Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   JN057_RS04575 Genome accession   NZ_CP071871
Coordinates   886675..888915 (+) Length   746 a.a.
NCBI ID   WP_000942420.1    Uniprot ID   A0A4J1ZPJ8
Organism   Streptococcus pneumoniae strain BVJ1JL     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 881675..893915
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JN057_RS04545 (JN057_00933) - 881838..882806 (+) 969 WP_000658180.1 PhoH family protein -
  JN057_RS04550 (JN057_00934) - 882986..883486 (+) 501 WP_000566988.1 GNAT family N-acetyltransferase -
  JN057_RS04555 (JN057_00935) - 883489..883815 (+) 327 Protein_909 TfoX/Sxy family protein -
  JN057_RS04560 (JN057_00937) ald 884116..885227 (-) 1112 Protein_910 alanine dehydrogenase -
  JN057_RS04565 (JN057_00938) - 885404..885973 (+) 570 WP_000443745.1 GNAT family N-acetyltransferase -
  JN057_RS04570 (JN057_00939) comEA/celA/cilE 886041..886691 (+) 651 WP_000387352.1 helix-hairpin-helix domain-containing protein Machinery gene
  JN057_RS04575 (JN057_00940) comEC/celB 886675..888915 (+) 2241 WP_000942420.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  JN057_RS04580 - 889094..889282 (+) 189 WP_001812421.1 hypothetical protein -
  JN057_RS04585 (JN057_00941) - 889315..889902 (+) 588 WP_000939895.1 ATP-binding cassette domain-containing protein -
  JN057_RS04590 (JN057_00942) - 889906..891090 (+) 1185 WP_000655953.1 hypothetical protein -
  JN057_RS04595 (JN057_00944) infC 891403..891933 (+) 531 WP_000848180.1 translation initiation factor IF-3 -
  JN057_RS04600 (JN057_00945) rpmI 891966..892166 (+) 201 WP_001125943.1 50S ribosomal protein L35 -
  JN057_RS04605 (JN057_00946) rplT 892218..892577 (+) 360 WP_000124836.1 50S ribosomal protein L20 -
  JN057_RS04610 (JN057_00947) - 892635..893015 (+) 381 WP_000157154.1 VOC family protein -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 84639.13 Da        Isoelectric Point: 9.4311

>NTDB_id=548614 JN057_RS04575 WP_000942420.1 886675..888915(+) (comEC/celB) [Streptococcus pneumoniae strain BVJ1JL]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCLFIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQN
LVDSVERVRILPDTIKVNGDSLSFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
LKTQGIYQTLNIKRIQSFQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLISLALVYDLRKNIKGLTVLSLLITGLFFLTK
YPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
ENVGDLSEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQQGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGVDSWKIESVR

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=548614 JN057_RS04575 WP_000942420.1 886675..888915(+) (comEC/celB) [Streptococcus pneumoniae strain BVJ1JL]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTGTTACTATGGCTTTACTACGCCATTTT
CTCAGTATCCTATTTTGCTTTGTTGGGTTTTGTTTTTCTGCTAGTCTGCCTCTTTATCCAATTTCCTTGGAAATCAGCAG
GTAAAGTTCTAGTGATTTGTGGAGTCTTTGGCTTCTGGTTTCTGTTTCAAACTTGGCAACAGAGTCAAGTGAGTCAAAAT
TTGGTGGATTCTGTTGAAAGGGTACGGATTTTACCAGACACTATTAAGGTTAACGGTGACAGTCTGTCCTTTCGTGGTAA
GTCTGATGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACTGACC
TTCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTGACTACCAAGGCTAT
CTGAAGACTCAGGGAATTTACCAGACACTCAATATTAAAAGAATCCAGTCATTCCAAAAGGTTGGCAGTTGGGATATAGG
TGAAAACCTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGATGCACTTCCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTAGGACATCTGGACACCGATTTTGAGGAGATGAATGAGCTTTATTCCAGTTTAGGAATTATTCACCTT
TTTGCCTTGTCAGGTATGCAGGTAGGGTTTTTCATGGACGGATTTAAGAAACTACTTTTACGATTGGGCTTGACACAAGA
AAAGTTGAAGTGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGTGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTACTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTTTTTGACTTGGTCTTCTTACCGCTCTTGTCTATC
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTAGAGGGCATTATTCGCTTGGT
CTCGCAGGTGGCAAGGAGACCGCTTGTCTTTGGTCAACCCAATGCATGGCTTTTAATCTTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAGGATTAACAGTATTGAGTTTATTGATTACAGGTCTCTTTTTCCTTACCAAG
TATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGAATGTTGGAGATTTGTCAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGACAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACAAGGAAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGGTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(30-176)

Competence protein (Competence)

(216-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4J1ZPJ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus pneumoniae TIGR4

96.917

100

0.969
  comEC/celB Streptococcus pneumoniae Rx1

95.174

100

0.952
  comEC/celB Streptococcus pneumoniae D39

95.174

100

0.952
  comEC/celB Streptococcus pneumoniae R6

95.174

100

0.952
  comEC/celB Streptococcus mitis SK321

92.091

100

0.921
  comEC/celB Streptococcus mitis NCTC 12261

91.812

99.866

0.917
  comEC Lactococcus lactis subsp. cremoris KW2

44.534

99.33

0.442