Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   JZY07_RS04965 Genome accession   NZ_CP071305
Coordinates   990998..991840 (+) Length   280 a.a.
NCBI ID   WP_024400617.1    Uniprot ID   A0A9Q5G966
Organism   Streptococcus suis strain SC183     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 985998..996840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JZY07_RS04935 (JZY07_04935) - 986731..987381 (-) 651 WP_024400621.1 hemolysin III family protein -
  JZY07_RS04940 (JZY07_04940) - 987371..987922 (-) 552 WP_024383459.1 DUF1836 domain-containing protein -
  JZY07_RS04945 (JZY07_04945) - 988030..989682 (-) 1653 WP_024400620.1 FAD-dependent oxidoreductase -
  JZY07_RS04950 (JZY07_04950) - 989679..990002 (-) 324 WP_024412126.1 rhodanese-like domain-containing protein -
  JZY07_RS04955 (JZY07_04955) - 990111..990371 (+) 261 WP_009909865.1 metal-sensitive transcriptional regulator -
  JZY07_RS04960 (JZY07_04960) - 990382..990939 (+) 558 WP_024400618.1 sugar O-acetyltransferase -
  JZY07_RS04965 (JZY07_04965) dprA 990998..991840 (+) 843 WP_024400617.1 DNA-processing protein DprA Machinery gene
  JZY07_RS04970 (JZY07_04970) topA 991933..994026 (+) 2094 WP_024400616.1 type I DNA topoisomerase -
  JZY07_RS04975 (JZY07_04975) rplJ 994593..995087 (+) 495 WP_002936486.1 50S ribosomal protein L10 -
  JZY07_RS04980 (JZY07_04980) rplL 995153..995518 (+) 366 WP_002936483.1 50S ribosomal protein L7/L12 -
  JZY07_RS04985 (JZY07_04985) - 995717..995890 (+) 174 WP_032501787.1 hypothetical protein -
  JZY07_RS04990 (JZY07_04990) - 995887..996705 (+) 819 WP_024392289.1 replication initiator protein A -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31339.23 Da        Isoelectric Point: 8.4493

>NTDB_id=544865 JZY07_RS04965 WP_024400617.1 990998..991840(+) (dprA) [Streptococcus suis strain SC183]
MNNFELFKWKKAGLTNLNINKVLTYQERFGKKLSLRNIAVVSECKNPLLFMENYKNLDVKACREEFNRFPSFSILDDVYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGIQSVQKIIKELNNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDNIYPKENKDLQTYIGKHHLVLTEYEAGAQPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIISEYQF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=544865 JZY07_RS04965 WP_024400617.1 990998..991840(+) (dprA) [Streptococcus suis strain SC183]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCAGGTCTGACCAATCTCAACATCAATAAGGTATTGACTTATCAAGA
AAGATTTGGCAAAAAGCTATCCTTGCGCAATATCGCTGTCGTTTCTGAATGTAAAAATCCATTGTTATTCATGGAAAACT
ATAAGAATTTAGATGTCAAAGCCTGTCGGGAAGAATTTAACAGGTTTCCTTCTTTTTCGATTTTGGATGACGTCTATCCA
CTAGCATTGAAGCAAATTTACAATCCACCTGTACTTTTATTTTATCAAGGGGATTTAGAATTGCTAGAAAAATCAAAGCT
TGCAGTCGTTGGTACACGAAATGCCAGCAAAAATGGTATTCAGTCTGTTCAGAAGATTATCAAAGAACTCAACAATCGCT
TTGTCATTGTCAGTGGTTTGGCAAGAGGAATTGATACAGCTGCTCATATTGCTAGCCTGAAAAATGGTGGACAAACCATT
GCTGTAATCGGAACAGGTTTAGATAATATTTATCCAAAAGAAAATAAGGATTTGCAGACCTATATTGGAAAACACCATTT
GGTGCTGACAGAGTATGAAGCTGGTGCTCAGCCACTCAAATACCATTTTCCAGAACGCAATCGCATTATAGCTGGTTTGG
TGGAAGGATTGGTAGTCTGTGAAGCTAAGATGCGGTCTGGTAGCCTCATTACCTGCGAACGTGCCTTGGAAGAAGGAAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGAGCAAAGTG
CGTTACATCAGGCTTGGACATCATTTCTGAGTATCAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(73-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

71.786

100

0.718
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

64.286

100

0.643
  dprA/cilB/dalA Streptococcus pneumoniae D39

64.286

100

0.643
  dprA/cilB/dalA Streptococcus pneumoniae R6

64.286

100

0.643
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

64.286

100

0.643
  dprA/cilB/dalA Streptococcus mitis SK321

63.929

100

0.639
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

63.571

100

0.636
  dprA Lactococcus lactis subsp. cremoris KW2

60.357

100

0.604
  dprA Legionella pneumophila strain ERS1305867

40.299

95.714

0.386
  dprA Bacillus subtilis subsp. subtilis str. 168

49.091

78.571

0.386
  dprA Vibrio campbellii strain DS40M4

36.519

100

0.382
  dprA Latilactobacillus sakei subsp. sakei 23K

41.365

88.929

0.368