Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   JZI48_RS07505 Genome accession   NZ_CP071145
Coordinates   1532357..1532542 (+) Length   61 a.a.
NCBI ID   WP_012679954.1    Uniprot ID   C0M6G1
Organism   Streptococcus equi subsp. equi strain 470_007     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1501760..1532542 1532357..1532542 within 0


Gene organization within MGE regions


Location: 1501760..1532542
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JZI48_RS07325 (JZI48_07325) - 1501760..1503193 (-) 1434 WP_012679988.1 recombinase family protein -
  JZI48_RS07330 (JZI48_07330) - 1503325..1503528 (-) 204 WP_012679987.1 hypothetical protein -
  JZI48_RS07335 (JZI48_07335) - 1503531..1504700 (-) 1170 WP_012679986.1 DUF4041 domain-containing protein -
  JZI48_RS07340 (JZI48_07340) - 1504709..1505497 (-) 789 WP_012679985.1 helix-turn-helix transcriptional regulator -
  JZI48_RS07345 (JZI48_07345) - 1505729..1507071 (+) 1343 WP_165626751.1 IS3 family transposase -
  JZI48_RS07350 (JZI48_07350) - 1507089..1508336 (+) 1248 WP_012679984.1 PBSX family phage terminase large subunit -
  JZI48_RS07355 (JZI48_07355) - 1508348..1509850 (+) 1503 WP_050316050.1 phage portal protein -
  JZI48_RS07360 (JZI48_07360) - 1509831..1511408 (+) 1578 WP_042357165.1 phage head morphogenesis protein -
  JZI48_RS07365 (JZI48_07365) - 1511410..1511616 (+) 207 WP_003052398.1 hypothetical protein -
  JZI48_RS07370 (JZI48_07370) - 1511613..1512032 (+) 420 WP_012679981.1 HD domain-containing protein -
  JZI48_RS07375 (JZI48_07375) - 1512229..1512498 (+) 270 WP_012679979.1 hypothetical protein -
  JZI48_RS07380 (JZI48_07380) - 1512534..1512701 (+) 168 WP_012679978.1 hypothetical protein -
  JZI48_RS07385 (JZI48_07385) - 1512883..1513506 (+) 624 WP_042357153.1 DUF4355 domain-containing protein -
  JZI48_RS07390 (JZI48_07390) - 1513517..1513897 (+) 381 WP_012679976.1 head decoration protein -
  JZI48_RS07395 (JZI48_07395) - 1513900..1514949 (+) 1050 WP_012679975.1 major capsid protein -
  JZI48_RS07400 (JZI48_07400) - 1514960..1515226 (+) 267 WP_012679974.1 HeH/LEM domain-containing protein -
  JZI48_RS07405 (JZI48_07405) - 1515236..1515589 (+) 354 WP_012679973.1 phage head-tail connector protein -
  JZI48_RS07410 (JZI48_07410) - 1515586..1515894 (+) 309 WP_012679972.1 hypothetical protein -
  JZI48_RS07415 (JZI48_07415) - 1515875..1516240 (+) 366 WP_012679971.1 HK97-gp10 family putative phage morphogenesis protein -
  JZI48_RS07420 (JZI48_07420) - 1516237..1516626 (+) 390 WP_012679970.1 hypothetical protein -
  JZI48_RS07425 (JZI48_07425) - 1516702..1517227 (+) 526 Protein_1422 phage major tail protein, TP901-1 family -
  JZI48_RS07430 (JZI48_07430) - 1517289..1517648 (+) 360 WP_012679967.1 tail assembly chaperone -
  JZI48_RS07435 (JZI48_07435) - 1517756..1518019 (+) 264 WP_230197369.1 hypothetical protein -
  JZI48_RS07440 (JZI48_07440) - 1518036..1521290 (+) 3255 WP_012679965.1 tape measure protein -
  JZI48_RS07445 (JZI48_07445) - 1521322..1522101 (+) 780 WP_012679964.1 distal tail protein Dit -
  JZI48_RS07450 (JZI48_07450) - 1522098..1524155 (+) 2058 WP_050316055.1 phage tail spike protein -
  JZI48_RS07455 (JZI48_07455) - 1524155..1524862 (+) 708 WP_012679962.1 collagen-like protein -
  JZI48_RS07460 (JZI48_07460) - 1524864..1525478 (+) 615 WP_012679961.1 hypothetical protein -
  JZI48_RS07465 (JZI48_07465) - 1525489..1527393 (+) 1905 WP_012679960.1 gp58-like family protein -
  JZI48_RS07470 (JZI48_07470) - 1527402..1527833 (+) 432 WP_012679959.1 DUF1617 family protein -
  JZI48_RS07475 (JZI48_07475) - 1527836..1528450 (+) 615 WP_012679958.1 DUF1366 domain-containing protein -
  JZI48_RS07480 (JZI48_07480) - 1528463..1528753 (+) 291 WP_012679338.1 hypothetical protein -
  JZI48_RS07485 (JZI48_07485) - 1528756..1528935 (+) 180 WP_012679339.1 holin -
  JZI48_RS07490 (JZI48_07490) - 1529047..1530276 (+) 1230 WP_012679957.1 glucosaminidase domain-containing protein -
  JZI48_RS07495 (JZI48_07495) spek 1530401..1531180 (+) 780 WP_050316071.1 streptococcal pyrogenic exotoxin SpeK -
  JZI48_RS07500 (JZI48_07500) spel 1531447..1532235 (+) 789 WP_012679955.1 streptococcal pyrogenic exotoxin SpeL -
  JZI48_RS07505 (JZI48_07505) prx 1532357..1532542 (+) 186 WP_012679954.1 hypothetical protein Regulator

Sequence


Protein


Download         Length: 61 a.a.        Molecular weight: 6981.00 Da        Isoelectric Point: 3.8428

>NTDB_id=543191 JZI48_RS07505 WP_012679954.1 1532357..1532542(+) (prx) [Streptococcus equi subsp. equi strain 470_007]
MLTYEEFKQAIDHGYITGDVVMIVRKNGQIFDYVLPGEEVQPWEVVTVEAVADILNELQII

Nucleotide


Download         Length: 186 bp        

>NTDB_id=543191 JZI48_RS07505 WP_012679954.1 1532357..1532542(+) (prx) [Streptococcus equi subsp. equi strain 470_007]
ATGCTAACATACGAGGAATTTAAGCAAGCTATTGATCATGGATATATCACAGGAGACGTGGTCATGATCGTGCGTAAAAA
CGGACAGATATTTGATTATGTGTTGCCAGGGGAGGAAGTGCAGCCTTGGGAAGTGGTGACAGTCGAGGCAGTTGCTGATA
TTTTAAACGAATTACAAATTATTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB C0M6G1

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

74.138

95.082

0.705

  prx Streptococcus pyogenes MGAS315

69.492

96.721

0.672

  prx Streptococcus pyogenes MGAS8232

69.492

96.721

0.672

  prx Streptococcus pyogenes MGAS315

67.241

95.082

0.639

  prx Streptococcus pyogenes MGAS315

83.333

68.852

0.574

  prx Streptococcus pyogenes MGAS315

82.927

67.213

0.557

  prx Streptococcus pyogenes MGAS315

70.732

67.213

0.475