Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   JZI48_RS02450 Genome accession   NZ_CP071145
Coordinates   533262..533441 (-) Length   59 a.a.
NCBI ID   WP_002983481.1    Uniprot ID   -
Organism   Streptococcus equi subsp. equi strain 470_007     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 532632..572436 533262..533441 within 0


Gene organization within MGE regions


Location: 532632..572436
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JZI48_RS02450 (JZI48_02450) prx 533262..533441 (-) 180 WP_002983481.1 hypothetical protein Regulator
  JZI48_RS02455 (JZI48_02455) - 533508..534302 (-) 795 WP_050315918.1 DNA/RNA non-specific endonuclease -
  JZI48_RS02460 (JZI48_02460) - 534529..535725 (-) 1197 WP_012679341.1 glucosaminidase domain-containing protein -
  JZI48_RS02465 (JZI48_02465) - 535837..536016 (-) 180 WP_012679339.1 holin -
  JZI48_RS02470 (JZI48_02470) - 536019..536309 (-) 291 WP_012679338.1 hypothetical protein -
  JZI48_RS02475 (JZI48_02475) - 536322..536939 (-) 618 WP_050316075.1 DUF1366 domain-containing protein -
  JZI48_RS02480 (JZI48_02480) - 536942..537373 (-) 432 WP_050316074.1 DUF1617 family protein -
  JZI48_RS02485 (JZI48_02485) - 537382..539415 (-) 2034 WP_050316809.1 gp58-like family protein -
  JZI48_RS02490 (JZI48_02490) - 539434..540549 (-) 1116 WP_050315855.1 hyaluronoglucosaminidase -
  JZI48_RS02495 (JZI48_02495) - 540546..542540 (-) 1995 WP_050315856.1 phage tail protein -
  JZI48_RS02500 (JZI48_02500) - 542551..543312 (-) 762 WP_050315857.1 phage tail domain-containing protein -
  JZI48_RS02505 (JZI48_02505) - 543316..545763 (-) 2448 WP_050315858.1 phage tail tape measure protein -
  JZI48_RS02510 (JZI48_02510) - 545764..546381 (-) 618 WP_050315859.1 Gp15 family bacteriophage protein -
  JZI48_RS02515 (JZI48_02515) - 546389..546796 (-) 408 WP_050315860.1 hypothetical protein -
  JZI48_RS02520 (JZI48_02520) - 546816..547313 (-) 498 WP_050315861.1 hypothetical protein -
  JZI48_RS02525 (JZI48_02525) - 547317..547685 (-) 369 WP_050315862.1 hypothetical protein -
  JZI48_RS02530 (JZI48_02530) - 547688..548041 (-) 354 WP_050315863.1 minor capsid protein -
  JZI48_RS02535 (JZI48_02535) - 548038..548382 (-) 345 WP_050315864.1 putative minor capsid protein -
  JZI48_RS02540 (JZI48_02540) - 548376..548762 (-) 387 WP_050315865.1 hypothetical protein -
  JZI48_RS02545 (JZI48_02545) - 548765..549013 (-) 249 WP_050315866.1 hypothetical protein -
  JZI48_RS02550 (JZI48_02550) - 549024..549896 (-) 873 WP_050315867.1 hypothetical protein -
  JZI48_RS02555 (JZI48_02555) - 549898..550500 (-) 603 WP_050315868.1 hypothetical protein -
  JZI48_RS02560 (JZI48_02560) - 550485..550724 (-) 240 WP_050315869.1 hypothetical protein -
  JZI48_RS02565 (JZI48_02565) - 550810..551094 (-) 285 WP_050315870.1 hypothetical protein -
  JZI48_RS02570 (JZI48_02570) - 551146..551367 (-) 222 WP_050315871.1 CPCC family cysteine-rich protein -
  JZI48_RS02575 (JZI48_02575) - 551333..552943 (-) 1611 WP_050315872.1 phage minor capsid protein -
  JZI48_RS02580 (JZI48_02580) - 552943..554442 (-) 1500 WP_050315873.1 phage portal protein -
  JZI48_RS02585 (JZI48_02585) - 554452..555750 (-) 1299 WP_050315874.1 PBSX family phage terminase large subunit -
  JZI48_RS02590 (JZI48_02590) - 555740..556231 (-) 492 WP_349627896.1 terminase small subunit -
  JZI48_RS02595 (JZI48_02595) - 556436..556870 (-) 435 WP_050315875.1 ArpU family phage packaging/lysis transcriptional regulator -
  JZI48_RS02600 (JZI48_02600) - 556982..557185 (-) 204 WP_050315876.1 hypothetical protein -
  JZI48_RS02605 (JZI48_02605) - 557199..557948 (-) 750 WP_050315877.1 site-specific DNA-methyltransferase -
  JZI48_RS02610 (JZI48_02610) - 557953..558180 (-) 228 WP_050315878.1 hypothetical protein -
  JZI48_RS02615 (JZI48_02615) - 558191..558397 (-) 207 WP_050315879.1 hypothetical protein -
  JZI48_RS02620 (JZI48_02620) - 558394..558834 (-) 441 WP_050315880.1 YopX family protein -
  JZI48_RS10940 - 558902..559087 (-) 186 WP_050315881.1 hypothetical protein -
  JZI48_RS02625 (JZI48_02625) - 559090..559314 (-) 225 WP_050315882.1 hypothetical protein -
  JZI48_RS02630 (JZI48_02630) - 559311..559706 (-) 396 WP_050315883.1 RusA family crossover junction endodeoxyribonuclease -
  JZI48_RS02635 (JZI48_02635) - 559699..559917 (-) 219 WP_050315884.1 hypothetical protein -
  JZI48_RS02640 (JZI48_02640) - 560195..562468 (-) 2274 WP_050315885.1 AAA family ATPase -
  JZI48_RS02645 (JZI48_02645) - 562477..564060 (-) 1584 WP_050315886.1 DEAD/DEAH box helicase -
  JZI48_RS02650 (JZI48_02650) - 564060..564644 (-) 585 WP_050315887.1 hypothetical protein -
  JZI48_RS02655 (JZI48_02655) - 564666..565400 (-) 735 WP_050315888.1 hypothetical protein -
  JZI48_RS02660 (JZI48_02660) - 565402..565824 (-) 423 WP_050315889.1 hypothetical protein -
  JZI48_RS02665 (JZI48_02665) - 565864..566943 (-) 1080 WP_050315890.1 ATP-binding protein -
  JZI48_RS02670 (JZI48_02670) - 566959..568278 (-) 1320 WP_050315891.1 AAA family ATPase -
  JZI48_RS02675 (JZI48_02675) - 568262..568504 (-) 243 WP_050315892.1 hypothetical protein -
  JZI48_RS02680 (JZI48_02680) - 568506..568682 (-) 177 WP_154235341.1 hypothetical protein -
  JZI48_RS02685 (JZI48_02685) - 568663..568809 (-) 147 WP_173476788.1 hypothetical protein -
  JZI48_RS02690 (JZI48_02690) - 568806..569090 (-) 285 WP_050315893.1 hypothetical protein -
  JZI48_RS02695 (JZI48_02695) - 569210..569413 (+) 204 WP_050315894.1 hypothetical protein -
  JZI48_RS02700 (JZI48_02700) - 569414..569569 (-) 156 WP_154235342.1 hypothetical protein -
  JZI48_RS02705 (JZI48_02705) - 569619..569825 (-) 207 WP_050315895.1 helix-turn-helix transcriptional regulator -
  JZI48_RS02710 (JZI48_02710) - 570009..570737 (+) 729 WP_231191385.1 helix-turn-helix transcriptional regulator -
  JZI48_RS02715 (JZI48_02715) - 570753..570971 (+) 219 WP_050315896.1 DUF6290 family protein -
  JZI48_RS02720 (JZI48_02720) - 570961..571236 (+) 276 WP_050315897.1 type II toxin-antitoxin system RelE/ParE family toxin -
  JZI48_RS02725 (JZI48_02725) - 571357..572436 (+) 1080 WP_050315898.1 tyrosine-type recombinase/integrase -

Sequence

Protein


Download         Length: 59 a.a.        Molecular weight: 6917.86 Da        Isoelectric Point: 4.1813

>NTDB_id=543155 JZI48_RS02450 WP_002983481.1 533262..533441(-) (prx) [Streptococcus equi subsp. equi strain 470_007]
MLTYDEFKQAIDRGYIVEDTVTIVRKNGQIFDYVLPHEKVKNGEVVTDEKVEEVLMELE

Nucleotide


Download         Length: 180 bp        

>NTDB_id=543155 JZI48_RS02450 WP_002983481.1 533262..533441(-) (prx) [Streptococcus equi subsp. equi strain 470_007]
ATGCTAACATACGACGAATTTAAGCAAGCTATTGACCGTGGATATATCGTAGAAGACACAGTCACGATCGTGCGTAAAAA
CGGACAGATTTTTGATTATGTGTTGCCACATGAGAAAGTAAAGAATGGAGAAGTTGTGACAGACGAAAAAGTAGAAGAAG
TGCTGATGGAATTGGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

87.931

98.305

0.864
  prx Streptococcus pyogenes MGAS8232

87.931

98.305

0.864
  prx Streptococcus pyogenes MGAS315

79.661

100

0.797
  prx Streptococcus pyogenes MGAS315

71.186

100

0.712
  prx Streptococcus pyogenes MGAS315

86.047

72.881

0.627
  prx Streptococcus pyogenes MGAS315

87.805

69.492

0.61
  prx Streptococcus pyogenes MGAS315

76.19

71.186

0.542