NTDB

Overview

Name	comEA	Type	Machinery gene
Locus tag	JRY11_RS06865	Genome accession	NZ_CP070382
Coordinates	1272275..1272922 (+)	Length	215 a.a.
NCBI ID	WP_023188531.1	Uniprot ID	A0AAW7IZF3
Organism	Lactococcus lactis strain KF140
Function	dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1267275..1277922

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JRY11_RS06840 (JRY11_001373)	-	1267404..1268582 (+)	1179	WP_012898345.1	SLC13 family permease	-
JRY11_RS06845 (JRY11_001374)	-	1268755..1269318 (+)	564	WP_004255233.1	GNAT family N-acetyltransferase	-
JRY11_RS06850 (JRY11_001375)	-	1269422..1269820 (+)	399	WP_023188528.1	hypothetical protein	-
JRY11_RS06855 (JRY11_001376)	-	1269925..1270857 (+)	933	WP_025016985.1	ABC transporter ATP-binding protein	-
JRY11_RS06860 (JRY11_001377)	-	1270854..1272215 (+)	1362	WP_023188530.1	ABC transporter permease	-
JRY11_RS06865 (JRY11_001378)	comEA	1272275..1272922 (+)	648	WP_023188531.1	ComEA family DNA-binding protein	Machinery gene
JRY11_RS06870 (JRY11_001379)	comEC	1272903..1275113 (+)	2211	WP_179107682.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
JRY11_RS06875 (JRY11_001380)	-	1275398..1276174 (+)	777	WP_023188533.1	alpha/beta hydrolase family protein	-
JRY11_RS06880 (JRY11_001381)	-	1276359..1276574 (+)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
JRY11_RS06885 (JRY11_001382)	atpB	1276619..1277332 (+)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
JRY11_RS06890 (JRY11_001383)	atpF	1277347..1277853 (+)	507	WP_004255258.1	F0F1 ATP synthase subunit B	-

Sequence

Protein

Download Length: 215 a.a. Molecular weight: 23624.76 Da Isoelectric Point: 4.8659

                                >NTDB_id=539606 JRY11_RS06865 WP_023188531.1 1272275..1272922(+) (comEA) [Lactococcus lactis strain KF140]

MDKILEKVKEYWKMIVLVVCGLIAGGIFYVLTNGQKPTTNLSVENLSSVSRQSSVSKFSEPNEKSVSKIMVDLKGAVTKP

NVYQISSDERLVDIIKEAGGFTDQADQKSINLSAKLKDEEVIYVPKIGENSSTENTDSSANSVTSQVSTTTEKININQAD

LTELQKLTGVGQKKAQDIIDFRTKNGDFKSLEDLGKVSGFGDKTLEKLKDELCFE

Nucleotide

Download Length: 648 bp

                                >NTDB_id=539606 JRY11_RS06865 WP_023188531.1 1272275..1272922(+) (comEA) [Lactococcus lactis strain KF140]

ATGGATAAGATTTTAGAAAAAGTAAAAGAATATTGGAAAATGATTGTTTTAGTTGTTTGTGGGCTCATTGCTGGTGGGAT

TTTTTACGTTTTAACCAACGGTCAAAAGCCAACTACAAATCTGTCAGTAGAAAATTTAAGTTCTGTCAGCAGGCAAAGCT

CTGTCAGTAAATTTAGTGAACCTAATGAAAAATCTGTCAGTAAAATTATGGTTGATTTAAAAGGTGCGGTAACAAAGCCT

AATGTCTATCAAATTTCGTCAGATGAACGTCTAGTTGATATAATTAAGGAAGCTGGTGGTTTTACTGACCAAGCTGACCA

GAAATCAATTAATCTGTCAGCAAAATTAAAAGATGAAGAAGTAATTTATGTCCCAAAAATTGGTGAAAATTCAAGCACAG

AAAATACTGATAGCTCTGCTAATTCGGTCACTAGTCAAGTCTCAACAACCACTGAAAAAATAAATATCAATCAAGCAGAT

TTGACTGAACTACAAAAATTAACAGGTGTTGGTCAGAAAAAAGCTCAAGACATCATCGATTTTCGGACGAAAAATGGTGA

TTTCAAATCACTTGAAGACTTGGGAAAAGTTTCTGGTTTTGGAGATAAAACACTAGAAAAATTGAAAGATGAGTTGTGTT

TTGAATAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(70-125)

Helix-hairpin-helix motif (HHH_3)

(151-212)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comEA	Lactococcus lactis subsp. cremoris KW2	75.688	100	0.767
comEA/celA/cilE	Streptococcus mitis SK321	44.907	100	0.451
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	43.578	100	0.442
comEA/celA/cilE	Streptococcus pneumoniae Rx1	41.553	100	0.423
comEA/celA/cilE	Streptococcus pneumoniae D39	41.553	100	0.423
comEA/celA/cilE	Streptococcus pneumoniae R6	41.553	100	0.423
comEA/celA/cilE	Streptococcus mitis NCTC 12261	41.743	100	0.423
comEA	Latilactobacillus sakei subsp. sakei 23K	36.564	100	0.386

Detailed information NTG0539606