Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   I6K87_RS04135 Genome accession   NZ_CP069892
Coordinates   830636..831337 (-) Length   233 a.a.
NCBI ID   WP_059220602.1    Uniprot ID   -
Organism   Streptococcus anginosus strain FDAARGOS_1357     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 825636..836337
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K87_RS04110 (I6K87_04110) rnc 825946..826644 (-) 699 WP_049534586.1 ribonuclease III -
  I6K87_RS04115 (I6K87_04115) - 827018..827376 (-) 359 Protein_805 YbaN family protein -
  I6K87_RS04120 (I6K87_04120) - 827457..828407 (+) 951 Protein_806 IS30 family transposase -
  I6K87_RS04125 (I6K87_04125) vicX 828485..829288 (-) 804 WP_003027672.1 MBL fold metallo-hydrolase Regulator
  I6K87_RS04130 (I6K87_04130) micB 829291..830643 (-) 1353 WP_003027674.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6K87_RS04135 (I6K87_04135) micA 830636..831337 (-) 702 WP_059220602.1 response regulator YycF Regulator
  I6K87_RS04140 (I6K87_04140) - 831621..831962 (-) 342 WP_049533028.1 hypothetical protein -
  I6K87_RS04145 (I6K87_04145) - 831989..833302 (-) 1314 WP_022525097.1 glycosyltransferase family 4 protein -
  I6K87_RS04150 (I6K87_04150) - 833304..834302 (-) 999 WP_049533026.1 glycosyltransferase family 4 protein -
  I6K87_RS04155 (I6K87_04155) ccpA 834482..835486 (-) 1005 WP_049533025.1 catabolite control protein A Regulator

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26929.94 Da        Isoelectric Point: 4.6211

>NTDB_id=537239 I6K87_RS04135 WP_059220602.1 830636..831337(-) (micA) [Streptococcus anginosus strain FDAARGOS_1357]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAERPDILILDLMLPEMDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAALTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLYHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=537239 I6K87_RS04135 WP_059220602.1 830636..831337(-) (micA) [Streptococcus anginosus strain FDAARGOS_1357]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATAAAGTTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACAGCCTTCGACGGTCGCGAAGCGTTAGAAATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTGA
TGTTGCCCGAAATGGATGGTTTAGAGGTGGCGCGAACGATTCGGAAAACGAGTAATGTGCCAATCATCGTTCTTTCTGCC
AAAGACAGTGAATTTGACAAAGTTATTGGTCTTGAAATCGGTGCGGATGACTATATGACAAAGCCTTTCTCTAATCGTGA
GTTGCAGGCGCGTGTTAAAGCCATTTTGCGGCGGACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCTGACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACTGATGCTTTTGTCGTGAAAAAGCATGGCGAAGAATTAGATTTAACACAC
CGTGAGTTTGAATTGCTCTACCATTTGGCAACGCATATCGGGCAAGTGATGACGCGTGAACATCTGCTAGAAACGGTGTG
GGGTTATGATTATTTTGGAGATGTACGGACGGTCGATGTGACAATTCGCCGTTTGAGAGAAAAGATTGAGGATATTCCTA
GCCGACCAGAGTATATTTTAACACGGCGTGGCGTTGGATATTACATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.833

100

0.828
  vicR Streptococcus mutans UA159

78.814

100

0.798
  covR Streptococcus salivarius strain HSISS4

45.217

98.712

0.446
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  scnR Streptococcus mutans UA159

36.522

98.712

0.361